Abstract 1076: Hexavalent HERA-CD40L induces a productive T cell-mediated anti-tumor immune response and shows superior activity in comparison to benchmark CD40 agonistic antibodies
Gieffers, Christian, Richards, David M., Sykora, Jaromir, Merz, Christian, Sefrin, Julian P., Billian-Frey, Katharina, Heinonen, Karl, Müller, Mauricio Redondo, Schröder, Matthias, Thiemann, Meinolf, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Neutralization of the CD95 ligand by APG101 inhibits invasion of glioma cells in vitro
Merz, Christian, Strecker, Alexander, Sykora, Jaromir, Hill, Oliver, Fricke, Harald, Angel, Peter, Gieffers, Christian, Peterziel, Heike
Published in Anti-cancer drugs (01.08.2015)
Published in Anti-cancer drugs (01.08.2015)
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Abstract 1760: The hexavalent CD40 agonist HERA-CD40L augments multi-level crosstalk between T cells and antigen-presenting cells
Merz, Christian, Sykora, Jaromir, Marschall, Viola, Richards, David M., Thiemann, Meinolf, Fricke, Harald, Hill, Oliver, Gieffers, Christian
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 4143: The novel hexavalent human GITR agonist HERA-GITRL promotes anti-tumor efficacy independent of Fc-functionality and shows superior activity compared with the monoclonal anti-GITR antibody TRX518
Schröder, Matthias, Marshall, Viola, Thiemann, Meinolf, Richards, David M., Merz, Christian, Sykora, Jaromir, Sefrin, Julian P., Redondo-Müller, Mauricio, Heinonen, Karl, Billian-Frey, Katharina, Hill, Oliver, Gieffers, Christian
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Infiltration of circulating myeloid cells through CD95L contributes to neurodegeneration in mice
Gao, Liang, Brenner, David, Llorens-Bobadilla, Enric, Saiz-Castro, Gonzalo, Frank, Tobias, Wieghofer, Peter, Hill, Oliver, Thiemann, Meinolf, Karray, Saoussen, Prinz, Marco, Weishaupt, Jochen H, Martin-Villalba, Ana
Published in The Journal of experimental medicine (06.04.2015)
Published in The Journal of experimental medicine (06.04.2015)
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Journal Article
The Hexavalent CD40 Agonist HERA-CD40L Induces T-Cell-mediated Antitumor Immune Response Through Activation of Antigen-presenting Cells
Merz, Christian, Sykora, Jaromir, Marschall, Viola, Richards, David M, Heinonen, Karl, Redondo Müller, Mauricio, Thiemann, Meinolf, Schnyder, Tim, Fricke, Harald, Hill, Oliver, Gieffers, Christian
Published in Journal of immunotherapy (1997) (01.11.2018)
Published in Journal of immunotherapy (1997) (01.11.2018)
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Abstract 1688: HERA-CD40L: A novel hexavalent CD40 agonist with superior biological activity
Merz, Christian, Sykora, Jaromir, Thiemann, Meinolf, Marschall, Viola, Heinonen, Karl H., Fricke, Harald, Gieffers, Christian, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 3754: The novel hexavalent human CD137/4-1BB agonist HERA-CD137L promotes anti-cancer immunity by activating CD8 T cells while regulatory T cells are not affected
Thiemann, Meinolf, Sykora, Jaromir, Richards, David M., Merz, Christian, Marschall, Viola, Mueller, Mauricio Redondo, Sefrin, Julian P., Heinonen, Karl, Fricke, Harald, Gieffers, Christian, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 630: Novel hexavalent HVEM agonist HERA-LIGHT promotes T cell activation and expansion
Sefrin, Julian P., Richards, David M., Sykora, Jaromir, Thiemann, Meinolf, Merz, Christian, Marschall, Viola, Müller, Mauricio Redondo, Heinonen, Karl, Fricke, Harald, Gieffers, Christian, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 5015: HERA-CD40L a hexavalent CD40 agonist induces T cell mediated anti-tumor immune response and shows superior activity in direct comparison to benchmark agonistic antibodies
Gieffers, Christian, Sykora, Jaromir, Merz, Christian, Müller, Mauricio Redondo, Richards, David M., Sefrin, Julian, Billian-Frey, Katharina, Heinonen, Karl, Marschall, Viola, Schröder, Matthias, Fricke, Harald, Thiemann, Meinolf, Oliver, Hill
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 4845: HERA-CD27L, a true CD27 agonist, is a hexavalent CD27 ligand that enhances T cell activation and induces potent anti-tumor immunity
Sefrin, Julian P., Richards, David M., Billian-Frey, Katharina, Heinonen, Karl, Marschall, Viola, Merz, Christian, Müller, Mauricio Redondo, Schröder, Matthias, Sykora, Jaromir, Thiemann, Meinolf, Fricke, Harald, Gieffers, Christian, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Yes and PI3K Bind CD95 to Signal Invasion of Glioblastoma
Kleber, Susanne, Sancho-Martinez, Ignacio, Wiestler, Benedict, Beisel, Alexandra, Gieffers, Christian, Hill, Oliver, Thiemann, Meinolf, Mueller, Wolf, Sykora, Jaromir, Kuhn, Andreas, Schreglmann, Nina, Letellier, Elisabeth, Zuliani, Cecilia, Klussmann, Stefan, Teodorczyk, Marcin, Gröne, Hermann-Josef, Ganten, Tom M., Sültmann, Holger, Tüttenberg, Jochen, von Deimling, Andreas, Regnier-Vigouroux, Anne, Herold-Mende, Christel, Martin-Villalba, Ana
Published in Cancer cell (01.03.2008)
Published in Cancer cell (01.03.2008)
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Journal Article
The novel TRAIL-receptor agonist APG350 exerts superior therapeutic activity in pancreatic cancer cells
Legler, Karen, Hauser, Charlotte, Egberts, Jan-Hendrik, Willms, Anna, Heneweer, Carola, Boretius, Susann, Röcken, Christoph, Glüer, Claus-Christian, Becker, Thomas, Kluge, Michael, Hill, Oliver, Gieffers, Christian, Fricke, Harald, Kalthoff, Holger, Lemke, Johannes, Trauzold, Anna
Published in Cell death & disease (18.04.2018)
Published in Cell death & disease (18.04.2018)
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Abstract 1204: A construction platform for hexavalent agonists targeting receptors of the tumor necrosis factor superfamily: Where death meets co-stimulation
Merz, Christian, Gieffers, Christian, Kluge, Michael, Richards, David M., Schnyder, Tim, Sykora, Jaromir, Thiemann, Meinolf, Fricke, Harald, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 4690: Hexavalent CD27 agonists show single agent anti-tumor activity and enhanced memory formation in mouse syngeneic tumor models
Gieffers, Christian, Richards, David, Sykora, Jaromir, Redondo-Müller, Mauricio, Thiemann, Meinolf, Merz, Christian, Heinonen, Karl Heinonen, Marschall, Viola, Fricke, Harald, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract 4963: Novel hexavalent GITR agonists stimulate T cells and enhance memory formation
Thiemann, Meinolf, Gieffers, Christian, Richards, David M., Merz, Christian, Heinonen, Karl, Mueller, Mauricio Redondo, Marschall, Viola, Sykora, Jaromir, Fricke, Harald, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 4986: APG101 inhibits CD95-Ligand induced invasion of glioblastoma in 3D-models in vitro and ex vivo
Merz, Christian, Strecker, Alexander, Sykora, Jaromir, Hill, Oliver, Christian, Gieffers, Fricke, Harald, Angel, Peter, Peterziel, Heike
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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CD95-Ligand on Peripheral Myeloid Cells Activates Syk Kinase to Trigger Their Recruitment to the Inflammatory Site
Letellier, Elisabeth, Kumar, Sachin, Sancho-Martinez, Ignacio, Krauth, Stefanie, Funke-Kaiser, Anne, Laudenklos, Sabrina, Konecki, Katrin, Klussmann, Stefan, Corsini, Nina S., Kleber, Susanne, Drost, Natalia, Neumann, Andreas, Lévi-Strauss, Matthieu, Brors, Benedikt, Gretz, Norbert, Edler, Lutz, Fischer, Carmen, Hill, Oliver, Thiemann, Meinolf, Biglari, Bahram, Karray, Saoussen, Martin-Villalba, Ana
Published in Immunity (Cambridge, Mass.) (26.02.2010)
Published in Immunity (Cambridge, Mass.) (26.02.2010)
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