Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor
Finlay, M. Raymond V, Anderton, Mark, Ashton, Susan, Ballard, Peter, Bethel, Paul A, Box, Matthew R, Bradbury, Robert H, Brown, Simon J, Butterworth, Sam, Campbell, Andrew, Chorley, Christopher, Colclough, Nicola, Cross, Darren A. E, Currie, Gordon S, Grist, Matthew, Hassall, Lorraine, Hill, George B, James, Daniel, James, Michael, Kemmitt, Paul, Klinowska, Teresa, Lamont, Gillian, Lamont, Scott G, Martin, Nathaniel, McFarland, Heather L, Mellor, Martine J, Orme, Jonathon P, Perkins, David, Perkins, Paula, Richmond, Graham, Smith, Peter, Ward, Richard A, Waring, Michael J, Whittaker, David, Wells, Stuart, Wrigley, Gail L
Published in Journal of medicinal chemistry (23.10.2014)
Published in Journal of medicinal chemistry (23.10.2014)
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Journal Article
Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR)
Ward, Richard A, Anderton, Mark J, Ashton, Susan, Bethel, Paul A, Box, Matthew, Butterworth, Sam, Colclough, Nicola, Chorley, Christopher G, Chuaqui, Claudio, Cross, Darren A. E, Dakin, Les A, Debreczeni, Judit É, Eberlein, Cath, Finlay, M. Raymond V, Hill, George B, Grist, Matthew, Klinowska, Teresa C. M, Lane, Clare, Martin, Scott, Orme, Jonathon P, Smith, Peter, Wang, Fengjiang, Waring, Michael J
Published in Journal of medicinal chemistry (12.09.2013)
Published in Journal of medicinal chemistry (12.09.2013)
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Journal Article
Trypanosome alternative oxidase: from molecule to function
Chaudhuri, Minu, Ott, Robert Daniel, Hill, George C.
Published in Trends in parasitology (01.10.2006)
Published in Trends in parasitology (01.10.2006)
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Journal Article
Discovery, Synthesis, and in Vivo Activity of a New Class of Pyrazoloquinazolines as Selective Inhibitors of Aurora B Kinase
Mortlock, Andrew A, Foote, Kevin M, Heron, Nicola M, Jung, Frédéric H, Pasquet, Georges, Lohmann, Jean-Jacques M, Warin, Nicolas, Renaud, Fabrice, De Savi, Chris, Roberts, Nicola J, Johnson, Trevor, Dousson, Cyril B, Hill, George B, Perkins, David, Hatter, Glenn, Wilkinson, Robert W, Wedge, Stephen R, Heaton, Simon P, Odedra, Rajesh, Keen, Nicholas J, Crafter, Claire, Brown, Elaine, Thompson, Katherine, Brightwell, Stephen, Khatri, Liz, Brady, Madeleine C, Kearney, Sarah, McKillop, David, Rhead, Steve, Parry, Tony, Green, Stephen
Published in Journal of medicinal chemistry (03.05.2007)
Published in Journal of medicinal chemistry (03.05.2007)
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Journal Article
CYP51 from Trypanosoma cruzi: A Phyla-Specific Residue in the B' Helix Defines Substrate Preferences of Sterol 14 alpha -Demethylase
Lepesheva, Galina I, Zaitseva, Natalia G, Nes, WDavid, Zhou, Wenxu, Arase, Miharu, Liu, Jialin, Hill, George C, Waterman, Michael R
Published in The Journal of biological chemistry (10.02.2006)
Published in The Journal of biological chemistry (10.02.2006)
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Journal Article
Thick titanium dioxide films for semiconductor photocatalysis
Mills, Andrew, Hill, George, Bhopal, Sharan, Parkin, Ivan P., O’Neill, Shane A.
Published in Journal of photochemistry and photobiology. A, Chemistry. (21.08.2003)
Published in Journal of photochemistry and photobiology. A, Chemistry. (21.08.2003)
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Major Urological Cancer Surgery for Patients is Safe and Surgical Training Should Be Encouraged During the COVID-19 Pandemic: A Multicentre Analysis of 30-day Outcomes
Tan, Wei Shen, Arianayagam, Rajan, Khetrapal, Pramit, Rowe, Edward, Kearley, Samantha, Mahrous, Ahmed, Pal, Raj, Fowler, William, Heer, Rakesh, Elajnaf, Mohamed, Douglas-Moore, Jayne, Leyshon Griffiths, T.R., Voss, James, Wilby, Daniel, Al Kadhi, Omar, Noel, Jonathan, Vasdev, Nikhil, McKay, Alastair, Ahmad, Imran, Abu-Nayla, Islam, Lamb, Benjamin, Hill, George T., Narahari, Krishna, Kynaston, Howard, Yousuf, Arzu, Kusuma, Venkata R.M., Cresswell, Jo, Cooke, Pete, Chakravarti, Aniruddha, Barod, Ravi, Bex, Axel, Kelly, John D.
Published in European urology open science (Online) (01.03.2021)
Published in European urology open science (Online) (01.03.2021)
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Journal Article
SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors
Heron, Nicola M., Anderson, Malcolm, Blowers, David P., Breed, Jason, Eden, Jonathan M., Green, Stephen, Hill, George B., Johnson, Trevor, Jung, Frederic H., McMiken, Helen H.J., Mortlock, Andrew A., Pannifer, Andrew D., Pauptit, Richard A., Pink, Jennifer, Roberts, Nicola J., Rowsell, Siân
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Journal Article
Results of an assessment to identify potential barriers to sustainable agriculture on American Indian reservations in the Western United States
Singletary, Loretta, Emm, Staci, Brummer, Fara Ann, Hill, George C., Lewis, Steve, Hebb, Vicki
Published in The journal of agricultural education and extension (07.08.2016)
Published in The journal of agricultural education and extension (07.08.2016)
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Journal Article
Uniforms in the Middle School: Student Opinions, Discipline Data, and School Police Data
Sanchez, Jafeth E., Yoxsimer, Andrew, Hill, George C.
Published in Journal of school violence (01.10.2012)
Published in Journal of school violence (01.10.2012)
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Journal Article
Bioactive Compounds and Their Effect on Blood Pressure-A Review
Malinowski, Bartosz, Fajardo Leighton, Raul Ignacio, Hill, Christopher George, Szandorowski, Paweł, Wiciński, Michał
Published in Nutrients (03.06.2020)
Published in Nutrients (03.06.2020)
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Journal Article
Discovery of Novel and Potent Thiazoloquinazolines as Selective Aurora A and B Kinase Inhibitors
Jung, Frédéric H, Pasquet, Georges, Lambert-van der Brempt, Christine, Lohmann, Jean-Jacques M, Warin, Nicolas, Renaud, Fabrice, Germain, Hervé, De Savi, Chris, Roberts, Nicola, Johnson, Trevor, Dousson, Cyril, Hill, George B, Mortlock, Andrew A, Heron, Nicola, Wilkinson, Robert W, Wedge, Stephen R, Heaton, Simon P, Odedra, Rajesh, Keen, Nicholas J, Green, Stephen, Brown, Elaine, Thompson, Katherine, Brightwell, Stephen
Published in Journal of medicinal chemistry (09.02.2006)
Published in Journal of medicinal chemistry (09.02.2006)
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