Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics
Froning, Karen, Maguire, Jack, Sereno, Arlene, Huang, Flora, Chang, Shawn, Weichert, Kenneth, Frommelt, Anton J, Dong, Jessica, Wu, Xiufeng, Austin, Heather, Conner, Elaine M, Fitchett, Jonathan R, Heng, Aik Roy, Balasubramaniam, Deepa, Hilgers, Mark T, Kuhlman, Brian, Demarest, Stephen J
Published in Nature communications (11.05.2020)
Published in Nature communications (11.05.2020)
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Journal Article
Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy
Gharbi, Severine Isabelle, Pelletier, Laura A, Espada, Alfonso, Gutiérrez, Jesus, Sanfeliciano, Sonia Maria Gutiérrez, Rauch, Charles T, Ganado, Maria Patricia, Baquero, Carmen, Zapatero, Elisabet, Zhang, Aiping, Benach, Jordi, Russell, Anna-Maria, Cano, Leticia, Gomez, Sandra, Broughton, Howard, Pulliam, Nicholas, Perez, Carmen Maria, Torres, Raquel, Debets, Marjoke F, de Dios, Alfonso, Puig, Oscar, Hilgers, Mark T, Lallena, Maria Jose
Published in NPJ breast cancer (29.11.2022)
Published in NPJ breast cancer (29.11.2022)
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Journal Article
Author Correction: Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy
Gharbi, Severine Isabelle, Pelletier, Laura A, Espada, Alfonso, Gutiérrez, Jesus, Sanfeliciano, Sonia Maria Gutiérrez, Rauch, Charles T, Ganado, Maria Patricia, Baquero, Carmen, Zapatero, Elisabet, Zhang, Aiping, Benach, Jordi, Russell, Anna-Maria, Cano, Leticia, Gomez, Sandra, Broughton, Howard, Pulliam, Nicholas, Perez, Carmen Maria, Torres, Raquel, Debets, Marjoke F, de Dios, Alfonso, Puig, Oscar, Hilgers, Mark T, Lallena, Maria Jose
Published in NPJ breast cancer (28.12.2022)
Published in NPJ breast cancer (28.12.2022)
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Journal Article
Structures of the N-Terminal Modules Imply Large Domain Motions during Catalysis by Methionine Synthase
Evans, John C, Huddler, Donald P, Hilgers, Mark T, Romanchuk, Gail, Matthews, Rowena G, Ludwig, Martha L
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2004)
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Journal Article
Crystal Structure of the Quorum-Sensing Protein LuxS Reveals a Catalytic Metal Site
Hilgers, Mark T., Ludwig, Martha L.
Published in Proceedings of the National Academy of Sciences - PNAS (25.09.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (25.09.2001)
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Journal Article
Crystal Structures of Active Fully Assembled Substrate- and Product-Bound Complexes of UDP-N-Acetylmuramic Acid:l-Alanine Ligase (MurC) from Haemophilus influenzae
Mol, Clifford D, Brooun, Alexei, Dougan, Douglas R, Hilgers, Mark T, Tari, Leslie W, Wijnands, Robert A, Knuth, Mark W, McRee, Duncan E, Swanson, Ronald V
Published in Journal of Bacteriology (01.07.2003)
Published in Journal of Bacteriology (01.07.2003)
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Journal Article
Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7‑(Benzimidazol-1-yl)-2,4-diaminoquinazolines
Lam, Thanh, Hilgers, Mark T, Cunningham, Mark L, Kwan, Bryan P, Nelson, Kirk J, Brown-Driver, Vickie, Ong, Voon, Trzoss, Michael, Hough, Grayson, Shaw, Karen Joy, Finn, John
Published in Journal of medicinal chemistry (13.02.2014)
Published in Journal of medicinal chemistry (13.02.2014)
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Journal Article
Comparison of the Essential Cellular Functions of the Two murA Genes of Bacillus anthracis
KEDAR, G. C, BROWN-DRIVER, Vickie, REYES, Daniel R, HILGERS, Mark T, STIDHAM, Mark A, SHAW, Karen Joy, FINN, John, HASELBECK, Robert J
Published in Antimicrobial Agents and Chemotherapy (01.06.2008)
Published in Antimicrobial Agents and Chemotherapy (01.06.2008)
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Journal Article
Evaluation of the metS and murB Loci for Antibiotic Discovery Using Targeted Antisense RNA Expression Analysis in Bacillus anthracis
KEDAR, G. C, BROWN-DRIVER, Vickie, REYES, Daniel R, HILGERS, Mark T, STIDHAM, Mark A, SHAW, Karen Joy, FINN, John, HASELBECK, Robert J
Published in Antimicrobial Agents and Chemotherapy (01.05.2007)
Published in Antimicrobial Agents and Chemotherapy (01.05.2007)
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Journal Article
Identification of Bacteria-Selective Threonyl-tRNA Synthetase Substrate Inhibitors by Structure-Based Design
Teng, Min, Hilgers, Mark T, Cunningham, Mark L, Borchardt, Allen, Locke, Jeffrey B, Abraham, Sunny, Haley, Gregory, Kwan, Bryan P, Hall, Courtney, Hough, Grayson W, Shaw, Karen J, Finn, John
Published in Journal of medicinal chemistry (28.02.2013)
Published in Journal of medicinal chemistry (28.02.2013)
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Journal Article
Crystallization of 11-Beta-Hydroxysteroid Dehydrogenase type 1
Aertgeerts, Kathleen, Brodsky, Oleg, Chi, Ellen, Hilgers, Mark T, Hosfield, David J, Skene, Robert J
Year of Publication 10.07.2007
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Year of Publication 10.07.2007
Patent
Crystallization of 11-Beta-Hydroxysteroid Dehydrogenase type 1
AERTGEERTS KATHLEEN, CHI ELLEN, BRODSKY OLEG, HOSFIELD DAVID J, SKENE ROBERT J, HILGERS MARK T
Year of Publication 10.07.2007
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Year of Publication 10.07.2007
Patent
Crystallization of histone deacetylase 2
Cronin, Ciaran N, Hilgers, Mark T, Knuth, Mark W, Navre, Marc E, Sang, Bi Ching, Skene, Robert J, Tari, Leslie W, Wilson, Keith P, Witmer, Darbi, Zou, Hua
Year of Publication 24.03.2009
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Year of Publication 24.03.2009
Patent
Crystallization of histone deacetylase 2
NAVRE MARC E, WILSON KEITH P, KNUTH MARK W, WITMER DARBI, SANG BI CHING, SKENE ROBERT J, ZOU HUA, HILGERS MARK T, CRONIN CIARAN N, TARI LESLIE W
Year of Publication 24.03.2009
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Year of Publication 24.03.2009
Patent
METHOD AND SYSTEM FOR PRODUCING FLEECE FROM FIBERS
MAGER JENS, HILGERS MARK, LETTOWSKY CHRISTOPH, ROSNER ANDREAS, STELTER CHRISTIAN, VODENCAREVIC ASMIR, FETT THOMAS
Year of Publication 16.07.2019
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Year of Publication 16.07.2019
Patent
섬유 플리스를 제조하는 방법 및 장치
MAGER JENS, HILGERS MARK, LETTOWSKY CHRISTOPH, STELTER CHRISTIAN, VODENCAREVIC ASMIR, FETT THOMAS, ROESNER ANDREAS
Year of Publication 11.06.2019
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Year of Publication 11.06.2019
Patent