Negative regulators of TGF-β1 signaling in renal fibrosis; pathological mechanisms and novel therapeutic opportunities
Gifford, Cody C, Tang, Jiaqi, Costello, Angelica, Khakoo, Nidah S, Nguyen, Tri Q, Goldschmeding, Roel, Higgins, Paul J, Samarakoon, Rohan
Published in Clinical science (1979) (29.01.2021)
Published in Clinical science (1979) (29.01.2021)
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Cancer-Associated Fibroblasts: Mechanisms of Tumor Progression and Novel Therapeutic Targets
Czekay, Ralf-Peter, Cheon, Dong-Joo, Samarakoon, Rohan, Kutz, Stacie M, Higgins, Paul J
Published in Cancers (27.02.2022)
Published in Cancers (27.02.2022)
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PAI-1 induction during kidney injury promotes fibrotic epithelial dysfunction via deregulation of klotho, p53, and TGF-β1-receptor signaling
Gifford, Cody C, Lian, Fei, Tang, Jiaqi, Costello, Angelica, Goldschmeding, Roel, Samarakoon, Rohan, Higgins, Paul J
Published in The FASEB journal (01.07.2021)
Published in The FASEB journal (01.07.2021)
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Journal Article
Deregulation of Hippo-TAZ pathway during renal injury confers a fibrotic maladaptive phenotype
Anorga, Sandybell, Overstreet, Jessica M, Falke, Lucas L, Tang, Jiaqi, Goldschmeding, Roel G, Higgins, Paul J, Samarakoon, Rohan
Published in The FASEB journal (01.05.2018)
Published in The FASEB journal (01.05.2018)
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Journal Article
Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species
Samarakoon, Rohan, Dobberfuhl, Amy D., Cooley, Catherine, Overstreet, Jessica M., Patel, Samik, Goldschmeding, Roel, Meldrum, Kirstan K., Higgins, Paul J.
Published in Cellular signalling (01.11.2013)
Published in Cellular signalling (01.11.2013)
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The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1
Samarakoon, Rohan, Higgins, Stephen P, Higgins, Craig E, Higgins, Paul J
Published in Biomolecules (Basel, Switzerland) (03.08.2019)
Published in Biomolecules (Basel, Switzerland) (03.08.2019)
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Journal Article
SERPINE1: Role in Cholangiocarcinoma Progression and a Therapeutic Target in the Desmoplastic Microenvironment
Czekay, Ralf-Peter, Higgins, Craig E, Aydin, Hasan Basri, Samarakoon, Rohan, Subasi, Nusret Bekir, Higgins, Stephen P, Lee, Hwajeong, Higgins, Paul J
Published in Cells (Basel, Switzerland) (07.05.2024)
Published in Cells (Basel, Switzerland) (07.05.2024)
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Editorial: The Role of Steroid Hormones and Growth Factors in Cancer
Cernera, Gustavo, Di Donato, Marzia, Higgins, Paul J, Schlaepfer, Isabel R
Published in Frontiers in cell and developmental biology (12.04.2022)
Published in Frontiers in cell and developmental biology (12.04.2022)
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CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment
Law, Mary E, Ferreira, Renan B, Davis, Bradley J, Higgins, Paul J, Kim, Jae-Sung, Castellano, Ronald K, Chen, Sixue, Luesch, Hendrik, Law, Brian K
Published in Breast cancer research : BCR (05.08.2016)
Published in Breast cancer research : BCR (05.08.2016)
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PAI-1: An Integrator of Cell Signaling and Migration
Czekay, Ralf-Peter, Wilkins-Port, Cynthia E., Higgins, Stephen P., Freytag, Jennifer, Overstreet, Jessica M., Klein, R. Matthew, Higgins, Craig E., Samarakoon, Rohan, Higgins, Paul J.
Published in International Journal of Cell Biology (2011)
Published in International Journal of Cell Biology (2011)
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TGF-β signaling in tissue fibrosis: Redox controls, target genes and therapeutic opportunities
Samarakoon, Rohan, Overstreet, Jessica M., Higgins, Paul J.
Published in Cellular signalling (01.01.2013)
Published in Cellular signalling (01.01.2013)
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