Antibody mediated therapy targeting CD47 inhibits tumor progression of hepatocellular carcinoma
Xiao, Zhenyu, Chung, Haniee, Banan, Babak, Manning, Pamela T, Ott, Katherine C, Lin, Shin, Capoccia, Benjamin J, Subramanian, Vijay, Hiebsch, Ronald R, Upadhya, Gundumi A, Mohanakumar, Thalachallour, Frazier, William A, Lin, Yiing, Chapman, William C
Published in Cancer letters (01.05.2015)
Published in Cancer letters (01.05.2015)
Get full text
Journal Article
Novel SIRPα Antibodies That Induce Single-Agent Phagocytosis of Tumor Cells while Preserving T Cells
Andrejeva, Gabriela, Capoccia, Benjamin J, Hiebsch, Ronald R, Donio, Michael J, Darwech, Isra M, Puro, Robyn J, Pereira, Daniel S
Published in The Journal of immunology (1950) (15.02.2021)
Published in The Journal of immunology (1950) (15.02.2021)
Get full text
Journal Article
Development of AO-176, a Next-Generation Humanized Anti-CD47 Antibody with Novel Anticancer Properties and Negligible Red Blood Cell Binding
Puro, Robyn J, Bouchlaka, Myriam N, Hiebsch, Ronald R, Capoccia, Benjamin J, Donio, Michael J, Manning, Pamela T, Frazier, William A, Karr, Robert W, Pereira, Daniel S
Published in Molecular cancer therapeutics (01.03.2020)
Published in Molecular cancer therapeutics (01.03.2020)
Get full text
Journal Article
CD47 blockade reduces ischemia/reperfusion injury and improves survival in a rat liver transplantation model
Xiao, Zhen‐Yu, Banan, Babak, Jia, Jianluo, Manning, Pamela T., Hiebsch, Ronald R., Gunasekaran, Muthukumar, Upadhya, Gundumi A., Frazier, William A., Mohanakumar, Thalachallour, Lin, Yiing, Chapman, William C.
Published in Liver transplantation (01.04.2015)
Published in Liver transplantation (01.04.2015)
Get full text
Journal Article
CD47 blockade reduces ischemia-reperfusion injury and improves outcomes in a rat kidney transplant model
Lin, Yiing, Manning, Pamela T, Jia, Jianluo, Gaut, Joseph P, Xiao, Zhenyu, Capoccia, Benjamin J, Chen, Chun-Cheng, Hiebsch, Ronald R, Upadhya, Gundumi, Mohanakumar, Thalachallour, Frazier, William A, Chapman, William C
Published in Transplantation (27.08.2014)
Published in Transplantation (27.08.2014)
Get more information
Journal Article
Attenuation of Ischemia-Reperfusion Injury and Improvement of Survival in Recipients of Steatotic Rat Livers Using CD47 Monoclonal Antibody
Xiao, Zhenyu, Banan, Babak, Xu, Min, Jia, Jianluo, Manning, Pamela T, Hiebsch, Ronald R, Gunasekaran, Muthukumar, Upadhya, Gundumi A, Frazier, William A, Mohanakumar, Thalachallour, Lin, Yiing, Chapman, William C
Published in Transplantation (01.07.2016)
Published in Transplantation (01.07.2016)
Get more information
Journal Article
Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation
PARLOW, John J, BURNEY, Mary W, WOERNDLE, Rhonda S, ENNIS, Michael D, CASE, Brenda L, GIRARD, Thomas J, HALL, Kerri A, HIEBSCH, Ronald R, HUFF, Rita M, LACHANCE, Rhonda M, MISCHKE, Deborah A, RAPP, Stephen R
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Get full text
Journal Article
Piperazinyl-glutamate-pyrimidines as potent P2Y12 antagonists for inhibition of platelet aggregation
PARLOW, John J, BURNEY, Mary W, WOERNDLE, Rhonda S, ENNIS, Michael D, CASE, Brenda L, GIRARD, Thomas J, HALL, Kerri A, HIEBSCH, Ronald R, HUFF, Rita M, LACHANCE, Rhonda M, MISCHKE, Deborah A, RAPP, Stephen R
Published in Bioorganic & medicinal chemistry letters (01.11.2009)
Published in Bioorganic & medicinal chemistry letters (01.11.2009)
Get full text
Journal Article
Part II: Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation
PARLOW, John J, BURNEY, Mary W, RAPP, Stephen R, WOERNDLE, Rhonda S, ENNIS, Michael D, CASE, Brenda L, GIRARD, Thomas J, HALL, Kerri A, HARRIS, Peter K, HIEBSCH, Ronald R, HUFF, Rita M, LACHANCE, Rhonda M, MISCHKE, Deborah A
Published in Bioorganic & medicinal chemistry letters (15.02.2010)
Published in Bioorganic & medicinal chemistry letters (15.02.2010)
Get full text
Journal Article
AO-176, a Differentiated Clinical-Stage Anti-CD47 Antibody, Demonstrates Potent Anti-Tumor Activity across Multiple Preclinical Models of B Cell Neoplasms
Wilson, William Casey, Richards, John O, Andrejeva, Gabriela, Capoccia, Benjamin J, Puro, Robyn J, Donio, Mike J, Hiebsch, Ronald R, Kashyap, Arun K, Pereira, Daniel S
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
Get full text
Journal Article
Abstract 954: AO-176, a highly differentiated clinical stage anti-CD47 antibody, is efficacious in pre-clinical models of lymphoma
Capoccia, Benjamin J., Donio, Michael J., Richards, John O., Hiebsch, Ronald R., Puro, Robyn J., Kashyap, Arun K., Pereira, Daniel S.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Get full text
Journal Article
AO-176, a Highly Differentiated Clinical Stage Anti-CD47 Antibody, Exerts Potent Anti-Tumor Activity in Preclinical Models of Multiple Myeloma As a Single Agent and in Combination with Approved Therapeutics
Wilson, William Casey, Richards, John, Puro, Robyn J, Andrejeva, Gabriela, Capoccia, Ben J, Donio, Mike J, Hiebsch, Ronald R, Chakraborty, Prabir, Sung, Victoria, Pereira, Daniel S
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
Get full text
Journal Article
Highly Differentiated Anti-CD47 Antibody, AO-176, Potently Inhibits Hematologic Malignancies Alone and in Combination
Richards, John, Bouchlaka, Myriam N, Puro, Robyn J, Capoccia, Ben J, Hiebsch, Ronald R, Donio, Michael J, Wilson, W. Casey, Chakraborty, Prabir, Sung, Victoria, Pereira, Daniel S
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
Get full text
Journal Article
Abstract 548: Evaluation of novel SIRP antibodies as potential cancer therapeutics
Hiebsch, Ronald R., Bouchlaka, Myriam N., Capoccia, Benjamin J., Donio, Michael J., Chakraborty, Prabir, Wilson, W. Casey, Puro, Robyn J., Pereira, Daniel S.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
Abstract 540: AO-176, a normal cell sparing humanized anti-CD47 antibody
Chakraborty, Prabir, Bouchlaka, Myriam N., Capoccia, Benjamin J., Hiebsch, Ronald R., Donio, Michael J., Puro, Robyn J., Sung, Vicki, Pereira, Daniel S.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
Therapeutic Potential of AO-176, a Next Generation Humanized CD47 Antibody, for Hematologic Malignancies
Wilson, W. Casey, Bouchlaka, Myriam N, Capoccia, Ben J, Hiebsch, Ronald R, Donio, Michael J, Puro, Robyn J, Carter, Alun J, Chakraborty, Prabir, Manning, Pamela T, Karr, Robert W, Sung, Vicki, Pereira, Daniel S
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
Get full text
Journal Article
Dual-Function Anti-CD47mAbs Induce Tumor Cell Death and Promote Phagocytosis Resulting in Enhanced in Vivo Efficacy
Manning, Pamela T., Capoccia, Benjamin J., Rettig, Michael P., Hiebsch, Ronald R., Karr, Robert W., DiPersio, John F., Frazier, William A.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
Get full text
Journal Article
Piperazinyl Glutamate Pyridines as Potent Orally Bioavailable P2Y(12) Antagonists for Inhibition of Platelet Aggregation
Parlow, John J., Burney, Mary W., Case, Brenda L., Girard, Thomas J., Hall, Kerri A., Harris, Peter K., Hiebsch, Ronald R., Huff, Rita M., Lachance, Rhonda M., Mischke, Deborah A., Rapp, Stephen R., Woerndle, Rhonda S., Ennis, Michael D.
Published in Journal of medicinal chemistry (11.03.2010)
Published in Journal of medicinal chemistry (11.03.2010)
Get full text
Journal Article