Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates
Mandal, Mihirbaran, Xiao, Li, Pan, Weidong, Scapin, Giovanna, Li, Guoqing, Tang, Haiqun, Yang, Shu-Wei, Pan, Jianping, Root, Yuriko, de Jesus, Reynalda Keh, Yang, Christine, Prosise, Winnie, Dayananth, Priya, Mirza, Asra, Therien, Alex G., Young, Katherine, Flattery, Amy, Garlisi, Charles, Zhang, Rumin, Chu, Donald, Sheth, Payal, Chu, Inhou, Wu, Jin, Markgraf, Carrie, Kim, Hai-Young, Painter, Ronald, Mayhood, Todd W., DiNunzio, Edward, Wyss, Daniel F., Buevich, Alexei V., Fischmann, Thierry, Pasternak, Alexander, Dong, Shuzhi, Hicks, Jacqueline D., Villafania, Artjohn, Liang, Lianzhu, Murgolo, Nicholas, Black, Todd, Hagmann, William K., Tata, Jim, Parmee, Emma R., Weber, Ann E., Su, Jing, Tang, Haifeng
Published in Journal of medicinal chemistry (22.12.2022)
Published in Journal of medicinal chemistry (22.12.2022)
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Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration
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Published in Journal of medicinal chemistry (14.03.2024)
Published in Journal of medicinal chemistry (14.03.2024)
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A Synthesis of a Spirocyclic Macrocyclic Protease Inhibitor for the Treatment of Hepatitis C
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Published in Organic letters (18.03.2016)
Published in Organic letters (18.03.2016)
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Year of Publication 20.03.2023
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Year of Publication 20.03.2023
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Year of Publication 21.02.2023
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Year of Publication 21.02.2023
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Fragment-based screening approach reveals non-orthosteric pockets in the search for allosteric inhibitors of tau-tubulin kinase 1
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Published in Acta crystallographica. Section A, Foundations and advances (07.07.2023)
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Year of Publication 02.07.2015
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NOVEL CYCLIC AZABENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS
LI BING, APGAR JAMES M, WILKENING ROBERT R, LEAVITT KENNETH J, CHU LIN, FENG DANQING, ANAND RAJAN, JIANG JINLONG, CHEN PING, QIAN XIAOXIA, DROPINSKI JAMES F, BIFTU TESFAYE, KIM ALEXANDER J, SEBHAT IYASSU, HICKS JACQUELINE D, WEI LAN, COLANDREA VINCENT J, DONG GUIZHEN, WU ZHICAI
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Year of Publication 26.11.2013
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Year of Publication 19.06.2024
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Year of Publication 19.06.2024
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Year of Publication 04.09.2024
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TIAN, Maoqun, HICKS, Jacqueline, D, ZHAO, Zhiqiang, SINZ, Christopher, J, SHARP, Phillip Patrick, SHEARN-NANCE, Galen Paul, LOMBARDO, Matthew, J, BAO, Jianming, KUANG, Rongze, LOPEZ, Jovan Alexander, CHENG, Alan, C, YANG, Song, WU, Zhicai, MERCHANT, Rohan
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Year of Publication 07.08.2024
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Debenham, John S, Wei, Lan, Ali, Amjad, Yang, Dexi, Tatosian, Daniel A, Gao, Ying-Duo, Hruza, Alan, Kuang, Rongze, HICKS, Jacqueline D, Nizner, Peter
Year of Publication 01.06.2023
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Year of Publication 01.06.2023
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DEBENHAM, John S, NIZNER, Peter, TATOSIAN, Daniel A, KUANG, Rongze, ALI, Amjad, HICKS, Jacqueline D, GAO, Ying-Duo, YANG, Dexi, HRUZA, Alan, WEI, Lan
Year of Publication 22.03.2023
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Year of Publication 22.03.2023
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Year of Publication 28.12.2023
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Year of Publication 28.12.2023
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Lombardo, Matthew J, Cheng, Alan C, Sharp, Phillip Patrick, Wu, Zhicai, Bao, Jianming, Yang, Song, Zhao, Zhiqiang, Lopez, Jovan Alexander, Merchant, Rohan Rajiv, Kuang, Rongze, Tian, Maoqun, HICKS, Jacqueline D, Sinz, Christopher J, Shearn-Nance, Galen Paul
Year of Publication 02.11.2023
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Year of Publication 02.11.2023
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Year of Publication 14.08.2024
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Year of Publication 14.08.2024
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