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Pharmacokinetics, Safety and Tolerability of ABT-494, a Novel Selective JAK 1 Inhibitor, in Healthy Volunteers and Subjects with Rheumatoid Arthritis
Mohamed, Mohamed-Eslam F., Camp, Heidi S., Jiang, Ping, Padley, Robert J., Asatryan, Armen, Othman, Ahmed A.
Published in Clinical pharmacokinetics (01.12.2016)
Published in Clinical pharmacokinetics (01.12.2016)
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Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of the β-Lactamase Inhibitor Vaborbactam (RPX7009) in Healthy Adult Subjects
Griffith, David C., Loutit, Jeffery S., Morgan, Elizabeth E., Durso, Stephanie, Dudley, Michael N.
Published in Antimicrobial agents and chemotherapy (01.10.2016)
Published in Antimicrobial agents and chemotherapy (01.10.2016)
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Isocyanide-Based Multicomponent Reactions in Water: Advanced Green Tools for the Synthesis of Heterocyclic Compounds
Nasiriani, Tahereh, Javanbakht, Siamak, Nazeri, Mohammad Taghi, Farhid, Hassan, Khodkari, Vida, Shaabani, Ahmad
Published in Topics in current chemistry (2016) (01.12.2022)
Published in Topics in current chemistry (2016) (01.12.2022)
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Design, Characterization, Molecular Docking, and Insecticidal Activity of Some New Heterocyclic Compounds Containing Pyrazole Moiety against Spodoptera frugiperda (J.E. Smith) (Noctuidae: Lepidoptera)
El-Gaby, M. S. A., Hussein, M. F., Reheim, M. A. M. Abdel, Abdou, A., Fahmy, A. M., Drar, A. M., Gad, M. A.
Published in Russian journal of bioorganic chemistry (01.06.2024)
Published in Russian journal of bioorganic chemistry (01.06.2024)
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Safety and Efficacy of Dolutegravir in Treatment-Experienced Subjects With Raltegravir-Resistant HIV Type 1 Infection: 24-Week Results of the VIKING Study
Eron, Joseph J., Clotet, Bonaventura, Durant, Jacques, Katlama, Christine, Kumar, Princy, Lazzarin, Adriano, Poizot-Martin, Isabelle, Richmond, Gary, Soriano, Vincent, Ait-Khaled, Mounir, Fujiwara, Tamio, Huang, Jenny, Min, Sherene, Vavro, Cindy, Yeo, Jane
Published in The Journal of infectious diseases (01.03.2013)
Published in The Journal of infectious diseases (01.03.2013)
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Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects
Stone, Nimalie D., Dunaway, Shelia B., Flexner, Charles, Tierney, Camlin, Calandra, Gary B., Becker, Stephen, Cao, Ying-Jun, Wiggins, Ilene P., Conley, Jeanne, MacFarland, Ron T., Park, Jeong-Gun, Lalama, Christina, Snyder, Sally, Kallungal, Beatrice, Klingman, Karin L., Hendrix, Craig W.
Published in Antimicrobial Agents and Chemotherapy (01.07.2007)
Published in Antimicrobial Agents and Chemotherapy (01.07.2007)
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Meropenem-RPX7009 Concentrations in Plasma, Epithelial Lining Fluid, and Alveolar Macrophages of Healthy Adult Subjects
Wenzler, Eric, Gotfried, Mark H., Loutit, Jeffrey S., Durso, Stephanie, Griffith, David C., Dudley, Michael N., Rodvold, Keith A.
Published in Antimicrobial agents and chemotherapy (01.12.2015)
Published in Antimicrobial agents and chemotherapy (01.12.2015)
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A phase II, randomized, placebo‐controlled, double‐blind, multi‐dose study of SRT2104, a SIRT1 activator, in subjects with type 2 diabetes
Baksi, Arun, Kraydashenko, Oleg, Zalevkaya, Alsu, Stets, Roman, Elliott, Peter, Haddad, Jonathan, Hoffmann, Ethan, Vlasuk, George P., Jacobson, Eric W.
Published in British journal of clinical pharmacology (01.07.2014)
Published in British journal of clinical pharmacology (01.07.2014)
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Exposure‐Response Analyses for Upadacitinib Efficacy in Subjects With Atopic Dermatitis—Analyses of Phase 2b Study to Support Selection of Phase 3 Doses
Mohamed, Mohamed‐Eslam F., Gopalakrishnan, Sathej, Teixeira, Henrique D., Othman, Ahmed A.
Published in Journal of clinical pharmacology (01.05.2021)
Published in Journal of clinical pharmacology (01.05.2021)
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Gold-catalyzed synthesis of small-sized carbo- and heterocyclic compounds: A review
Kadiyala Kasi Ganesh, Goutham Kommuru, Yamini Vanipenta, Katari Naresh Kumar
Published in Heterocyclic Communications (18.03.2024)
Published in Heterocyclic Communications (18.03.2024)
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Preclinical Pharmacokinetics and First-in-Human Pharmacokinetics, Safety, and Tolerability of Velpatasvir, a Pangenotypic Hepatitis C Virus NS5A Inhibitor, in Healthy Subjects
Mogalian, Erik, German, Polina, Kearney, Brian P., Yang, Cheng Yong, Brainard, Diana, Link, John, McNally, John, Han, LingLing, Ling, John, Mathias, Anita
Published in Antimicrobial agents and chemotherapy (01.05.2017)
Published in Antimicrobial agents and chemotherapy (01.05.2017)
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The Case of Dolutegravir Plus Darunavir Antiretroviral Regimens: Is It Always Useful to Double the Drug Doses?
Cattaneo, Dario, Ridolfo, Anna Lisa, Giacomelli, Andrea, Castagna, Antonella, Dolci, Alberto, Antinori, Spinello, Gervasoni, Cristina
Published in Therapeutic drug monitoring (01.04.2025)
Published in Therapeutic drug monitoring (01.04.2025)
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A Phase I, Randomized, Double-Blinded, Placebo- and Moxifloxacin-Controlled, Four-Period Crossover Study To Evaluate the Effect of Gepotidacin on Cardiac Conduction as Assessed by 12-Lead Electrocardiogram in Healthy Volunteers
Hossain, Mohammad, Zhou, Meijian, Tiffany, Courtney, Dumont, Etienne, Darpo, Borje
Published in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (01.05.2017)
Published in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (01.05.2017)
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Safety, tolerability, and pharmacokinetics of the HIV integrase inhibitor dolutegravir given twice daily with rifampin or once daily with rifabutin: results of a phase 1 study among healthy subjects
Dooley, Kelly E, Sayre, Patrick, Borland, Julie, Purdy, Elizabeth, Chen, Shuguang, Song, Ivy, Peppercorn, Amanda, Everts, Stephanie, Piscitelli, Stephen, Flexner, Charles
Published in Journal of acquired immune deficiency syndromes (1999) (01.01.2013)
Published in Journal of acquired immune deficiency syndromes (1999) (01.01.2013)
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Pharmacokinetics and Safety of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor, in Healthy Volunteers
Min, Sherene, Song, Ivy, Borland, Julie, Chen, Shuguang, Lou, Yu, Fujiwara, Tamio, Piscitelli, Stephen C.
Published in Antimicrobial Agents and Chemotherapy (01.01.2010)
Published in Antimicrobial Agents and Chemotherapy (01.01.2010)
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Metabolism, Excretion, and Mass Balance of the HIV-1 Integrase Inhibitor Dolutegravir in Humans
Castellino, Stephen, Moss, Lee, Wagner, David, Borland, Julie, Song, Ivy, Chen, Shuguang, Lou, Yu, Min, Sherene S., Goljer, Igor, Culp, Amanda, Piscitelli, Stephen C., Savina, Paul M.
Published in Antimicrobial Agents and Chemotherapy (01.08.2013)
Published in Antimicrobial Agents and Chemotherapy (01.08.2013)
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