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Antiviral Activity, Safety, and Pharmacokinetics of Bictegravir as 10-Day Monotherapy in HIV-1-Infected Adults
Gallant, Joel E, Thompson, Melanie, DeJesus, Edwin, Voskuhl, Gene W, Wei, Xuelian, Zhang, Heather, White, Kirsten, Cheng, Andrew, Quirk, Erin, Martin, Hal
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Published in Journal of acquired immune deficiency syndromes (1999) (01.05.2017)
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Preferential Inhibition of JAK1 Relative to JAK3 by Upadacitinib: Exposure‐Response Analyses of Ex Vivo Data From 2 Phase 1 Clinical Trials and Comparison to Tofacitinib
Mohamed, Mohamed‐Eslam F., Beck, Denise, Camp, Heidi S., Othman, Ahmed A.
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Published in Journal of clinical pharmacology (01.02.2020)
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Tenofovir, emtricitabine, lamivudine and dolutegravir concentrations in plasma and urine following drug intake cessation in a randomized controlled directly observed pharmacokinetic trial to aid point-of-care testing
Else, Laura J, Dickinson, Laura, Edick, Stacey, Zyhowski, Ashley, Ho, Ken, Meyn, Leslie, Dilly-Penchala, Sujan, Thompson, Beth, Shaw, Victoria, Khoo, Saye, Brand, Rhonda M
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Published in Journal of antimicrobial chemotherapy (01.07.2024)
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ING116070: A Study of the Pharmacokinetics and Antiviral Activity of Dolutegravir in Cerebrospinal Fluid in HIV-1–Infected, Antiretroviral Therapy–Naive Subjects
Letendre, Scott L., Mills, Anthony M., Tashima, Karen T., Thomas, Deborah A., Min, Sherene S., Chen, Shuguang, Song, Ivy H., Piscitelli, Stephen C.
Published in Clinical infectious diseases (01.10.2014)
Published in Clinical infectious diseases (01.10.2014)
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The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central Aβ Pharmacodynamic Responses in Mice, Dogs, and Humans
May, Patrick C., Willis, Brian A., Lowe, Stephen L., Dean, Robert A., Monk, Scott A., Cocke, Patrick J., Audia, James E., Boggs, Leonard N., Borders, Anthony R., Brier, Richard A., Calligaro, David O., Day, Theresa A., Ereshefsky, Larry, Erickson, Jon A., Gevorkyan, Hykop, Gonzales, Celedon R., James, Douglas E., Jhee, Stanford S., Komjathy, Steven F., Li, Linglin, Lindstrom, Terry D., Mathes, Brian M., Martényi, Ferenc, Sheehan, Scott M., Stout, Stephanie L., Timm, David E., Vaught, Grant M., Watson, Brian M., Winneroski, Leonard L., Yang, Zhixiang, Mergott, Dustin J.
Published in The Journal of neuroscience (21.01.2015)
Published in The Journal of neuroscience (21.01.2015)
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Tetrathiafulvalene-annulated [28]hexaphyrin(1.1.1.1.1.1): a multi-electron donor system subject to conformational control
Jana, Atanu, Ishida, Masatoshi, Cho, Kevin, Ghosh, Sudip Kumar, Kwak, Kyuju, Ohkubo, Kei, Sung, Young Mo, Davis, Christina M., Lynch, Vincent M., Lee, Dongil, Fukuzumi, Shunichi, Kim, Dongho, Sessler, Jonathan L.
Published in Chemical communications (Cambridge, England) (01.01.2013)
Published in Chemical communications (Cambridge, England) (01.01.2013)
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The Effect of Dolutegravir on the Pharmacokinetics of Metformin in Healthy Subjects
Song, Ivy H, Zong, Jian, Borland, Julie, Jerva, Fred, Wynne, Brian, Zamek-Gliszczynski, Maciej J, Humphreys, Joan E, Bowers, Gary D, Choukour, Mike
Published in Journal of acquired immune deficiency syndromes (1999) (01.08.2016)
Published in Journal of acquired immune deficiency syndromes (1999) (01.08.2016)
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Upadacitinib is associated with clinical response and steroid-free remission for children and adolescents with inflammatory bowel disease
Runde, Joseph, Ryan, Kelsey, Hirst, Joseph, Lebowitz, Jonathan, Chen, Wenya, Brown, Jeffrey, Strople, Jennifer
Published in Journal of pediatric gastroenterology and nutrition (01.01.2025)
Published in Journal of pediatric gastroenterology and nutrition (01.01.2025)
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A phase 1 study to evaluate the effect of dolutegravir on renal function via measurement of iohexol and para‐aminohippurate clearance in healthy subjects
Koteff, Justin, Borland, Julie, Chen, Shuguang, Song, Ivy, Peppercorn, Amanda, Koshiba, Takaaki, Cannon, Courtney, Muster, Heather, Piscitelli, Stephen C.
Published in British journal of clinical pharmacology (01.04.2013)
Published in British journal of clinical pharmacology (01.04.2013)
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Renal function and the effects of vericiguat in patients with worsening heart failure with reduced ejection fraction: insights from the VICTORIA (Vericiguat Global Study in Subjects with HFrEF) trial
Voors, Adriaan A., Mulder, Hillary, Reyes, Eugene, Cowie, Martin R., Lassus, Johan, Hernandez, Adrian F., Ezekowitz, Justin A., Butler, Javed, O'Connor, Christopher M., Koglin, Joerg, Lam, Carolyn S.P., Pieske, Burkert, Roessig, Lothar, Ponikowski, Piotr, Anstrom, Kevin J., Armstrong, Paul W.
Published in European journal of heart failure (01.08.2021)
Published in European journal of heart failure (01.08.2021)
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Simplified dolutegravir dosing for children with HIV weighing 20 kg or more: pharmacokinetic and safety substudies of the multicentre, randomised ODYSSEY trial
Bollen, Pauline D J, Moore, Cecilia L, Mujuru, Hilda A, Makumbi, Shafic, Kekitiinwa, Adeodata R, Kaudha, Elisabeth, Parker, Anna, Musoro, Godfrey, Nanduudu, Annet, Lugemwa, Abbas, Amuge, Pauline, Hakim, James G, Rojo, Pablo, Giaquinto, Carlo, Colbers, Angela, Gibb, Diana M, Ford, Deborah, Turkova, Anna, Burger, David M
Published in The lancet HIV (01.08.2020)
Published in The lancet HIV (01.08.2020)
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Excretion, Mass Balance, and Metabolism of [14C]LY3202626 in Humans: An Interplay of Microbial Reduction, Reabsorption, and Aldehyde Oxidase Oxidation That Leads to an Extended Excretion Profile
Katyayan, Kishore, Yi, Ping, Monk, Scott, Cassidy, Kenneth
Published in Drug metabolism and disposition (01.08.2020)
Published in Drug metabolism and disposition (01.08.2020)
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Genetic barrier to resistance for dolutegravir
Llibre, Josep M, Pulido, Federico, García, Federico, García Deltoro, Miguel, Blanco, José L, Delgado, Rafael
Published in AIDS reviews (01.01.2015)
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Published in AIDS reviews (01.01.2015)
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Pharmacokinetics of dolutegravir in HIV-seronegative subjects with severe renal impairment
Weller, Stephen, Borland, Julie, Chen, Shuguang, Johnson, Mark, Savina, Paul, Wynne, Brian, Wajima, Toshihiro, Peppercorn, Amanda F., Piscitelli, Stephen C.
Published in European journal of clinical pharmacology (01.01.2014)
Published in European journal of clinical pharmacology (01.01.2014)
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Metabolism and Excretion of Asenapine in Healthy Male Subjects
van de Wetering-Krebbers, SFM, Jacobs, PL, Kemperman, GJ, Spaans, E, Peeters, PAM, Delbressine, LPC, van Iersel, MLPS
Published in Drug metabolism and disposition (01.04.2011)
Published in Drug metabolism and disposition (01.04.2011)
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