In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): A novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist
Glennon, Jeffrey C., Van Scharrenburg, Guus, Ronken, Eric, Hesselink, Mayke B., Reinders, Jan-Hendrik, Van Der Neut, Martina, Long, Stephen K., Feenstra, Rolf W., McCreary, Andrew C.
Published in Synapse (New York, N.Y.) (15.12.2006)
Published in Synapse (New York, N.Y.) (15.12.2006)
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Chronic Stress Decreases the Number of Parvalbumin-Immunoreactive Interneurons in the Hippocampus: Prevention by Treatment with a Substance P Receptor (NK ) Antagonist
CZEH, Boldizsär, SIMON, Märia, VAN DER HART, Marieke G. C, SCHMELTING, Barthel, HESSELINK, Mayke B, FUCHS, Eberhard
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2005)
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2005)
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Synthesis, Structure−Activity Relationships, and Biological Properties of 1-Heteroaryl-4-[ω-(1H-indol-3-yl)alkyl]piperazines, Novel Potential Antipsychotics Combining Potent Dopamine D2 Receptor Antagonism with Potent Serotonin Reuptake Inhibition
Smid, Pieter, Coolen, Hein K. A. C, Keizer, Hiskias G, van Hes, Rolf, de Moes, Jan-Peter, den Hartog, Arnold P, Stork, Bob, Plekkenpol, Rob H, Niemann, Leonarda C, Stroomer, Cees N. J, Tulp, Martin Th. M, van Stuivenberg, Herman H, McCreary, Andrew C, Hesselink, Mayke B, Herremans, Arnoud H. J, Kruse, Chris G
Published in Journal of medicinal chemistry (03.11.2005)
Published in Journal of medicinal chemistry (03.11.2005)
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Journal Article
Multi-modal characterisation of the neocortical clip model of focal cerebral ischaemia by MRI, behaviour and immunohistochemistry
Ashioti, Maria, Beech, John S, Lowe, Andrew S, Hesselink, Mayke B, Modo, Michael, Williams, Steve C.R
Published in Brain research (11.05.2007)
Published in Brain research (11.05.2007)
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SONU20176289, a compound combining partial dopamine D2 receptor agonism with specific serotonin reuptake inhibitor activity, affects neuroplasticity in an animal model for depression
MICHAEL-TITUS, Adina T, ALBERT, Monika, CZEH, Boldizsar, MICHAEL, Gregory J, MICHAELIS, Thomas, WATANABE, Takashi, FRAHM, Jens, PUDOVKINA, Olga, VAN DER HART, Marieke G. C, HESSELINK, Mayke B, FUCHS, Eberhard
Published in European journal of pharmacology (19.11.2008)
Published in European journal of pharmacology (19.11.2008)
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SLV310, a novel, potential antipsychotic, combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition
VAN HES, Rolf, SMID, Pieter, STROOMER, Cees N. J, TIPKER, Koos, TULP, Martin Th. M, VAN DER HEYDEN, Jan A. M, MCCREARY, Andrew C, HESSELINK, Mayke B, KRUSE, Chris G
Published in Bioorganic & medicinal chemistry letters (10.02.2003)
Published in Bioorganic & medicinal chemistry letters (10.02.2003)
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Journal Article
SONU20176289, a compound combining partial dopamine D 2 receptor agonism with specific serotonin reuptake inhibitor activity, affects neuroplasticity in an animal model for depression
Michael-Titus, Adina T., Albert, Monika, Michael, Gregory J., Michaelis, Thomas, Watanabe, Takashi, Frahm, Jens, Pudovkina, Olga, van der Hart, Marieke G.C., Hesselink, Mayke B., Fuchs, Eberhard, Czéh, Boldizsár
Published in European journal of pharmacology (19.11.2008)
Published in European journal of pharmacology (19.11.2008)
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Journal Article
SONU20176289, a compound combining partial dopamine D(2) receptor agonism with specific serotonin reuptake inhibitor activity, affects neuroplasticity in an animal model for depression
Michael-Titus, Adina T, Albert, Monika, Michael, Gregory J, Michaelis, Thomas, Watanabe, Takashi, Frahm, Jens, Pudovkina, Olga, van der Hart, Marieke G C, Hesselink, Mayke B, Fuchs, Eberhard, Czéh, Boldizsár
Published in European journal of pharmacology (19.11.2008)
Published in European journal of pharmacology (19.11.2008)
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SLV313 (1 -(2,3 -dihydro -benzo [1,4 ]dioxin -5 -yl ) -4-[5-(4-fluoro-phenyl)-pyridin-3-ylmethyl]-piperazine monohydrochloride) : A novel dopamine D2 receptor antagonist and 5-HTIA receptor agonist potential antipsychotic drug
MCCREARY, Andrew C, GLENNON, Jeffrey C, FEENSTRA, Rolf W, KRUSE, Chris G, ASHBY, Charles R, MELTZER, Herbert Y, ZHU LI, REINDERS, Jan-Hendrik, HESSELINK, Mayke B, LONG, Stephen K, HERREMANS, Arnoud H, VAN STUIVENBERG, Herman
Published in Neuropsychopharmacology (New York, N.Y.) (2007)
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Published in Neuropsychopharmacology (New York, N.Y.) (2007)
Journal Article
SLV313 (1-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-4- [5-(4-fluoro-phenyl)-pyridin-3-ylmethyl]-piperazine monohydrochloride): a novel dopamine D2 receptor antagonist and 5-HT1A receptor agonist potential antipsychotic drug
McCreary, Andrew C, Glennon, Jeffrey C, Ashby, Jr, Charles R, Meltzer, Herbert Y, Li, Zhu, Reinders, Jan-Hendrik, Hesselink, Mayke B, Long, Stephen K, Herremans, Arnoud H, van Stuivenberg, Herman, Feenstra, Rolf W, Kruse, Chris G
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2007)
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2007)
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Journal Article
SLV310, a novel, potential antipsychotic, combining potent dopamine D 2 receptor antagonism with serotonin reuptake inhibition
van Hes, Rolf, Smid, Pieter, Stroomer, Cees N.J, Tipker, Koos, Tulp, Martin Th.M, van der Heyden, Jan A.M, McCreary, Andrew C, Hesselink, Mayke B, Kruse, Chris G
Published in Bioorganic & medicinal chemistry letters (10.02.2003)
Published in Bioorganic & medicinal chemistry letters (10.02.2003)
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Journal Article
Synthesis, Structure−Activity Relationships, and Biological Properties of 1-Heteroaryl-4-[ω-(1 H -indol-3-yl)alkyl]piperazines, Novel Potential Antipsychotics Combining Potent Dopamine D 2 Receptor Antagonism with Potent Serotonin Reuptake Inhibition
Smid, Pieter, Coolen, Hein K. A. C., Keizer, Hiskias G., van Hes, Rolf, de Moes, Jan-Peter, den Hartog, Arnold P., Stork, Bob, Plekkenpol, Rob H., Niemann, Leonarda C., Stroomer, Cees N. J., Tulp, Martin Th. M., van Stuivenberg, Herman H., McCreary, Andrew C., Hesselink, Mayke B., Herremans, Arnoud H. J., Kruse, Chris G.
Published in Journal of medicinal chemistry (01.11.2005)
Published in Journal of medicinal chemistry (01.11.2005)
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