Nicotine Glucuronidation and the Human UDP-Glucuronosyltransferase UGT2B10
Kaivosaari, Sanna, Toivonen, Päivi, Hesse, Leah M, Koskinen, Mikko, Court, Michael H, Finel, Moshe
Published in Molecular pharmacology (01.09.2007)
Published in Molecular pharmacology (01.09.2007)
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Evidence for oxazepam as an in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion
He, Xi, Hesse, Leah M., Hazarika, Suwagmani, Masse, Gina, Harmatz, Jerold S., Greenblatt, David J., Court, Michael H.
Published in British journal of clinical pharmacology (01.11.2009)
Published in British journal of clinical pharmacology (01.11.2009)
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UDP Glucuronosyltransferase (UGT) 1A6 Pharmacogenetics: II. Functional Impact of the Three Most Common Nonsynonymous UGT1A6 Polymorphisms (S7A, T181A, and R184S)
Krishnaswamy, Soundararajan, Hao, Qin, Al-Rohaimi, Abdul, Hesse, Leah M, von Moltke, Lisa L, Greenblatt, David J, Court, Michael H
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
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Pharmacokinetic properties of zolpidem in elderly and young adults: possible modulation by testosterone in men
Olubodun, Joel O., Ochs, Hermann R., Von Moltke, Lisa L., Roubenoff, Ronenn, Hesse, Leah M., Harmatz, Jerold S., Shader, Richard I., Greenblatt, David J.
Published in British journal of clinical pharmacology (01.09.2003)
Published in British journal of clinical pharmacology (01.09.2003)
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Journal Article
Effect of Age on in Vitro Triazolam Biotransformation in Male Human Liver Microsomes
Patki, Kiran C, von Moltke, Lisa L, Harmatz, Jerold S, Hesse, Leah M, Court, Michael H, Greenblatt, David J
Published in The Journal of pharmacology and experimental therapeutics (01.03.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2004)
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CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants
HESSE, Leah M, VENKATAKRISHNAN, Karthik, COURT, Michael H, VON MOLTKE, Lisa L, DUAN, S. U. X, SHADER, Richard I, GREENBLATT, David J
Published in Drug metabolism and disposition (01.10.2000)
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Published in Drug metabolism and disposition (01.10.2000)
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Effect of zolpidem on human Cytochrome P450 activity, and on transport mediated by P-glycoprotein
von Moltke, Lisa L., Weemhoff, James L., Perloff, Michael D., Hesse, Leah M., Harmatz, Jerold S., Roth-Schechter, Barbara F., Greenblatt, David J.
Published in Biopharmaceutics & drug disposition (01.12.2002)
Published in Biopharmaceutics & drug disposition (01.12.2002)
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UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: I. Identification of polymorphisms in the 5'-regulatory and exon 1 regions, and association with human liver UGT1A6 gene expression and glucuronidation
Krishnaswamy, Soundararajan, Hao, Qin, Al-Rohaimi, Abdul, Hesse, Leah M, von Moltke, Lisa L, Greenblatt, David J, Court, Michael H
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
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Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes
Hesse, Leah M, He, Ping, Krishnaswamy, Soundararajan, Hao, Qin, Hogan, Kirk, von Moltke, Lisa L, Greenblatt, David J, Court, Michael H
Published in Pharmacogenetics (London) (01.04.2004)
Published in Pharmacogenetics (London) (01.04.2004)
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Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin
Hesse, Leah M, Sakai, Yumiko, Vishnuvardhan, Daesety, Li, Albert P, von Moltke, Lisa L, Greenblatt, David J
Published in Journal of pharmacy and pharmacology (01.09.2003)
Published in Journal of pharmacy and pharmacology (01.09.2003)
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UDP Glucuronosyltransferase (UGT) 1A6 Pharmacogenetics: I. Identification of Polymorphisms in the 5â²-Regulatory and Exon 1 Regions, and Association with Human Liver UGT1A6 Gene Expression and Glucuronidation
Soundararajan Krishnaswamy, Qin Hao, Abdul Al-Rohaimi, Leah M. Hesse, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
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