Targeting DNA Methylation and EZH2 Activity to Overcome Melanoma Resistance to Immunotherapy
Emran, Abdullah Al, Chatterjee, Aniruddha, Rodger, Euan J., Tiffen, Jessamy C., Gallagher, Stuart J., Eccles, Michael R., Hersey, Peter
Published in Trends in immunology (01.04.2019)
Published in Trends in immunology (01.04.2019)
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Programmed Death-Ligand 1 Expression and Response to the Anti-Programmed Death 1 Antibody Pembrolizumab in Melanoma
Daud, Adil I, Wolchok, Jedd D, Robert, Caroline, Hwu, Wen-Jen, Weber, Jeffrey S, Ribas, Antoni, Hodi, F Stephen, Joshua, Anthony M, Kefford, Richard, Hersey, Peter, Joseph, Richard, Gangadhar, Tara C, Dronca, Roxana, Patnaik, Amita, Zarour, Hassane, Roach, Charlotte, Toland, Grant, Lunceford, Jared K, Li, Xiaoyun Nicole, Emancipator, Kenneth, Dolled-Filhart, Marisa, Kang, S Peter, Ebbinghaus, Scot, Hamid, Omid
Published in Journal of clinical oncology (01.12.2016)
Published in Journal of clinical oncology (01.12.2016)
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PD-L1 expression in melanoma shows marked heterogeneity within and between patients: implications for anti-PD-1/PD-L1 clinical trials
Madore, Jason, Vilain, Ricardo E., Menzies, Alexander M., Kakavand, Hojabr, Wilmott, James S., Hyman, Jessica, Yearley, Jennifer H., Kefford, Richard F., Thompson, John F., Long, Georgina V., Hersey, Peter, Scolyer, Richard A.
Published in Pigment cell and melanoma research (01.05.2015)
Published in Pigment cell and melanoma research (01.05.2015)
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Pharmacodynamic Effects and Mechanisms of Resistance to Vemurafenib in Patients With Metastatic Melanoma
TRUNZER, Kerstin, PAVLICK, Anna C, HERSEY, Peter, LONG, Georgina V, LAWRENCE, Donald, OTT, Patrick A, AMARAVADI, Ravi K, LEWIS, Karl D, PUZANOV, Igor, LO, Roger S, KOEHLER, Astrid, KOCKX, Mark, SCHUCHTER, Lynn, SPLEISS, Olivia, SCHELL-STEVEN, Annette, GILBERT, Houston N, COCKEY, Louise, BOLLAG, Gideon, LEE, Richard J, JOE, Andrew K, SOSMAN, Jeffrey A, RIBAS, Antoni, GONZALEZ, Rene, MCARTHUR, Grant A, HUTSON, Thomas E, MOSCHOS, Stergios J, FLAHERTY, Keith T, KIM, Kevin B, WEBER, Jeffrey S
Published in Journal of clinical oncology (10.05.2013)
Published in Journal of clinical oncology (10.05.2013)
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PD-L1 Expression and Tumor-Infiltrating Lymphocytes Define Different Subsets of MAPK Inhibitor-Treated Melanoma Patients
Kakavand, Hojabr, Wilmott, James S, Menzies, Alexander M, Vilain, Ricardo, Haydu, Lauren E, Yearley, Jennifer H, Thompson, John F, Kefford, Richard F, Hersey, Peter, Long, Georgina V, Scolyer, Richard A
Published in Clinical cancer research (15.07.2015)
Published in Clinical cancer research (15.07.2015)
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SIRT6 haploinsufficiency induces BRAFV600E melanoma cell resistance to MAPK inhibitors via IGF signalling
Strub, Thomas, Ghiraldini, Flavia G., Carcamo, Saul, Li, Man, Wroblewska, Aleksandra, Singh, Rajendra, Goldberg, Matthew S., Hasson, Dan, Wang, Zichen, Gallagher, Stuart J., Hersey, Peter, Ma’ayan, Avi, Long, Georgina V., Scolyer, Richard A., Brown, Brian, Zheng, Bin, Bernstein, Emily
Published in Nature communications (24.08.2018)
Published in Nature communications (24.08.2018)
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Results of a Phase III, Randomized, Placebo-Controlled Study of Sorafenib in Combination With Carboplatin and Paclitaxel As Second-Line Treatment in Patients With Unresectable Stage III or Stage IV Melanoma
HAUSCHILD, Axel, AGARWALA, Sanjiv S, PESCHEL, Christian, SCHADENDORF, Dirk, GARBE, Claus, O'DAY, Steven, DAUD, Adil, WHITE, J. Michael, CHENGHUA XIA, PATEL, Kiran, KIRKWOOD, John M, KEILHOLZ, Ulrich, TREFZER, Uwe, HOGG, David, ROBERT, Caroline, HERSEY, Peter, EGGERMONT, Alexander, GRABBE, Stephan, GONZALEZ, Rene, GILLE, Jens
Published in Journal of clinical oncology (10.06.2009)
Published in Journal of clinical oncology (10.06.2009)
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Phase II Trial of Tremelimumab (CP-675,206) in Patients with Advanced Refractory or Relapsed Melanoma
KIRKWOOD, John M, LORIGAN, Paul, HERSEY, Peter, HAUSCHILD, Axel, ROBERT, Caroline, MCDERMOTT, David, MARSHALL, Margaret A, GOMEZ-NAVARRO, Jesus, LIANG, Jane Q, BULANHAGUI, Cecile A
Published in Clinical cancer research (01.02.2010)
Published in Clinical cancer research (01.02.2010)
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Lysine Demethylases: Promising Drug Targets in Melanoma and Other Cancers
Punnia-Moorthy, Gaya, Hersey, Peter, Emran, Abdullah Al, Tiffen, Jessamy
Published in Frontiers in genetics (16.06.2021)
Published in Frontiers in genetics (16.06.2021)
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MicroRNA-149, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma
Jin, Lei, Hu, Wang Lai, Jiang, Chen Chen, Wang, Jia Xu, Han, Chuan Chun, Chu, Ping, Zhang, Lin Jie, Thorne, Rick F, Wilmott, James, Scolyer, Richard A, Hersey, Peter, Zhang, Xu Dong, Wu, Mian
Published in Proceedings of the National Academy of Sciences - PNAS (20.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (20.09.2011)
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Bcl-2 Antisense (oblimersen sodium) Plus Dacarbazine in Patients With Advanced Melanoma: The Oblimersen Melanoma Study Group
BEDIKIAN, Agop Y, MILLWARD, Michael, KIRKWOOD, John M, HALUSKA, Frank G, PEHAMBERGER, Hubert, CORNY, Robert, GORE, Martin, TREFZER, Uwe, PAVLICK, Anna C, DECONTI, Ronald, HERSH, Evan M, HERSEY, Peter
Published in Journal of clinical oncology (10.10.2006)
Published in Journal of clinical oncology (10.10.2006)
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Somatic Copy Number Amplification and Hyperactivating Somatic Mutations of EZH2 Correlate With DNA Methylation and Drive Epigenetic Silencing of Genes Involved in Tumor Suppression and Immune Responses in Melanoma
Tiffen, Jessamy, Wilson, Stephen, Gallagher, Stuart J, Hersey, Peter, Filipp, Fabian V
Published in Neoplasia (New York, N.Y.) (01.02.2016)
Published in Neoplasia (New York, N.Y.) (01.02.2016)
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Modulation of NOXA and MCL-1 as a Strategy for Sensitizing Melanoma Cells to the BH3-Mimetic ABT-737
LUCAS, Keryn M, MOHANA-KUMARAN, Nethia, LAU, Diana, XU DONG ZHANG, HERSEY, Peter, HUANG, David C, WENINGER, Wolfgang, HAASS, Nikolas K, ALLEN, John D
Published in Clinical cancer research (01.02.2012)
Published in Clinical cancer research (01.02.2012)
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Apoptosis Induction in Human Melanoma Cells by Inhibition of MEK Is Caspase-Independent and Mediated by the Bcl-2 Family Members PUMA, Bim, and Mcl-1
Wang, Yu Fang, Jiang, Chen Chen, Kiejda, Kelly Anne, Gillespie, Susan, Zhang, Xu Dong, Hersey, Peter
Published in Clinical cancer research (15.08.2007)
Published in Clinical cancer research (15.08.2007)
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Oncogenic Activation of MEK/ERK Primes Melanoma Cells for Adaptation to Endoplasmic Reticulum Stress
Croft, Amanda, Tay, Kwang H., Boyd, Suzanah C., Guo, Su T., Jiang, Chen C., Lai, Fritz, Tseng, Hsin-Yi, Jin, Lei, Rizos, Helen, Hersey, Peter, Zhang, Xu D.
Published in Journal of investigative dermatology (01.02.2014)
Published in Journal of investigative dermatology (01.02.2014)
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The Epigenetic Regulator I-BET151 Induces BIM-Dependent Apoptosis and Cell Cycle Arrest of Human Melanoma Cells
Gallagher, Stuart J., Mijatov, Branka, Gunatilake, Dilini, Tiffen, Jessamy C., Gowrishankar, Kavitha, Jin, Lei, Pupo, Gulietta M., Cullinane, Carleen, Prinjha, Rab K., Smithers, Nicholas, McArthur, Grant A., Rizos, Helen, Hersey, Peter
Published in Journal of investigative dermatology (01.11.2014)
Published in Journal of investigative dermatology (01.11.2014)
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Differential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanoma
Carlino, Matteo S., Todd, Jason R., Gowrishankar, Kavitha, Mijatov, Branka, Pupo, Gulietta M., Fung, Carina, Snoyman, Stephanie, Hersey, Peter, Long, Georgina V., Kefford, Richard F., Rizos, Helen
Published in Molecular oncology (01.05.2014)
Published in Molecular oncology (01.05.2014)
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