APVO210: A Bispecific Anti-CD86-IL-10 Fusion Protein (ADAPTIR™) to Induce Antigen-Specific T Regulatory Type 1 Cells
Pellerin, Laurence, Chen, Ping, Gregori, Silvia, Hernandez-Hoyos, Gabriela, Bacchetta, Rosa, Roncarolo, Maria Grazia
Published in Frontiers in immunology (25.05.2018)
Published in Frontiers in immunology (25.05.2018)
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Journal Article
Regulation of GATA-3 expression during CD4 lineage differentiation
Gimferrer, Idoia, Hu, Taishan, Simmons, Amie, Wang, Chi, Souabni, Abdallah, Busslinger, Meinrad, Bender, Timothy P, Hernandez-Hoyos, Gabriela, Alberola-Ila, José
Published in The Journal of immunology (1950) (01.04.2011)
Published in The Journal of immunology (1950) (01.04.2011)
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Journal Article
851 Potent tumor-directed T cell activation and in vivo tumor inhibition induced by a 4–1BB x 5T4 ADAPTIR™ bispecific antibody
Nelson, Michelle, Miller, Robert, Nilsson, Anneli, Ljung, Lill, Chunyk, Allison, McMahan, Catherine, Bienvenue, David, Askmyr, Maria, Hernandez-Hoyos, Gabriela, Fritzell, Sara
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
이종이량체 PSMA 및 CD3-결합 이중특이적 항체
PAVLIK PETER, BIENVENUE DAVID LEONARD, GROSS JANE, MISHER LYNDA, HERNANDEZ HOYOS GABRIELA
Year of Publication 08.08.2023
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Year of Publication 08.08.2023
Patent
CD123 결합 단백질 그리고 관련된 조성물 및 방법
PAVLIK PETER, MITCHELL DANIELLE, BLANKENSHIP JOHN W, BIENVENUE DAVID, MCMAHAN CATHERINE J, HERNANDEZ HOYOS GABRIELA, SEWELL ELAINE T
Year of Publication 19.06.2019
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Year of Publication 19.06.2019
Patent
5T4 및 4-1BB에 결합하는 항원 결합 단백질 및 관련 조성물 및 방법
MITCHELL DANIELLE, VON SCHANTZ LAURA, SALL ANNA, MISHER LYNDA, BIENVENUE DAVID, FRITZELL SARA, VARAS LAURA, ELLMARK PETER, HERNANDEZ HOYOS GABRIELA, FUREBRING CHRISTINA
Year of Publication 08.04.2020
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Year of Publication 08.04.2020
Patent
Abstract LB173: APVO603: A dual 4-1BB and OX40 bispecific approach utilizing ADAPTIRTMtechnology designed to deliver a conditional T cell/NK response against solid tumors
Nelson, Michelle H., Miller, Robert E., Franke-Welch, Secil, Chenault, Ruth, Fang, Hang, Chunyk, Allison, Hernandez-Hoyos, Gabriela, Ramos, Hilario J., Bienvenue, David, McMahan, Catherine
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract LB172: APVO442: A bispecific T cell-engaging candidate utilizing the ADAPTIR-FLEXTMplatform technology with unique properties designed for optimal tumor distribution and cytotoxic response against PSMA-expressing solid tumors
Gottschalk, Rebecca, Miller, Robert E., Misher, Lynda, Nelson, Michelle H., Chunyk, Allison, Woodruff, Brian, Haglin, Elizabeth, Hernandez-Hoyos, Gabriela, Pavlik, Peter, McMahan, Catherine, Ramos, Hilario J., Bienvenue, David
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
MOR209/ES414, a Novel Bispecific Antibody Targeting PSMA for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Hernandez-Hoyos, Gabriela, Sewell, Toddy, Bader, Robert, Bannink, Jeannette, Chenault, Ruth A, Daugherty, Mollie, Dasovich, Maria, Fang, Hang, Gottschalk, Rebecca, Kumer, John, Miller, Robert E, Ravikumar, Padma, Wiens, Jennifer, Algate, Paul A, Bienvenue, David, McMahan, Catherine J, Natarajan, Sateesh K, Gross, Jane A, Blankenship, John W
Published in Molecular cancer therapeutics (01.09.2016)
Published in Molecular cancer therapeutics (01.09.2016)
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Journal Article
The Bispecific Tumor Antigen-Conditional 4-1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies
Nelson, Michelle H, Fritzell, Sara, Miller, Robert, Werchau, Doreen, Van Citters, Danielle, Nilsson, Anneli, Misher, Lynda, Ljung, Lill, Bader, Robert, Deronic, Adnan, Chunyk, Allison G, Schultz, Lena, Varas, Laura A, Rose, Nadia, Håkansson, Maria, Gross, Jane, Furebring, Christina, Pavlik, Peter, Sundstedt, Anette, Veitonmäki, Niina, Ramos, Hilario J, Säll, Anna, Dahlman, Anna, Bienvenue, David, von Schantz, Laura, McMahan, Catherine J, Askmyr, Maria, Hernandez-Hoyos, Gabriela, Ellmark, Peter
Published in Molecular cancer therapeutics (03.01.2023)
Published in Molecular cancer therapeutics (03.01.2023)
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Journal Article
Abstract 2380: Preclinical safety and efficacy of a tumor-directed T cell activating 4-1BB x 5T4 ADAPTIR™ bispecific antibody
Dahlman, Anna, Nelson, Michelle, Bannink, Jeannette, Johnson, Starrla, Werchau, Doreen, Nilsson, Anneli, Ljung, Lill, Blahnik-Fagan, Gabriele, Bader, Robert, Deronic, Adnan, Ellmark, Peter, Askmyr, Maria, Hernandez-Hoyos, Gabriela, McMahan, Cathy, Fritzell, Sara
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Activation of the CD137 Pathway in T cells by a CD137 × 5T4 bispecific ADAPTIR Molecule Requires Co-engagement of CD137 and 5T4
Blahnik-Fagan, Gabriele R., Bader, Robert, Bannink, Jeannette, Mitchell, Danielle, Misher, Lynda, McMahan, Cathy, Bienvenue, David, Fritzell, Sara, Säll, Anna, von Schantz, Laura, Ellmark, Peter, Nelson, Michelle, Hernandez-Hoyos, Gabriela
Published in The Journal of immunology (1950) (01.05.2018)
Published in The Journal of immunology (1950) (01.05.2018)
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Journal Article
Abstract B249: Prolonged cytotoxic activity induced by anti-PSMA x anti-CD3 ADAPTIR™ molecule in the absence of significant cytokine release
Hernandez-Hoyos, Gabriela, Sewell, Toddy, Ravikumar, Padma, Aguilar, Megan, Kumer, John, Bienvenue, David, McMahan, Catherine J., Gross, Jane, Blankenship, John W.
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Journal Article
Abstract 1236: Pharmacokinetic evaluation and tolerability assessment of anti-PSMA x anti-CD3 SCORPIONTM molecule in humanized mice and non-human primates
McMahan, Catherine J., Hernandez-Hoyos, Gabriela, Bannink, Jeannette, Bader, Robert R., Ravikumar, Padma, Sewell, Toddy, Bannink, Kenneth M., Gottschalk, Rebecca J., Fang, Hang, Johnson, Starrla, Aguilar, Megan, Kumer, John, Algate, Paul A., Bienvenue, David L., Blankenship, John W.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Constitutive Expression of PU.1 in Fetal Hematopoietic Progenitors Blocks T Cell Development at the Pro-T Cell Stage
Anderson, Michele K, Weiss, Angela H, Hernandez-Hoyos, Gabriela, Dionne, Christopher J, Rothenberg, Ellen V
Published in Immunity (Cambridge, Mass.) (01.02.2002)
Published in Immunity (Cambridge, Mass.) (01.02.2002)
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Journal Article