Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation
Shonesy, Brian C, Bluett, Rebecca J, Ramikie, Teniel S, Báldi, Rita, Hermanson, Daniel J, Kingsley, Philip J, Marnett, Lawrence J, Winder, Danny G, Colbran, Roger J, Patel, Sachin
Published in Cell reports (Cambridge) (11.12.2014)
Published in Cell reports (Cambridge) (11.12.2014)
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Journal Article
Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet
Wang, Bo, Rong, Xin, Duerr, Mark A., Hermanson, Daniel J., Hedde, Per Niklas, Wong, Jinny S., de Aguiar Vallim, Thomas Q., Cravatt, Benjamin F., Gratton, Enrico, Ford, David A., Tontonoz, Peter
Published in Cell metabolism (08.03.2016)
Published in Cell metabolism (08.03.2016)
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Journal Article
Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network
Xu, Shu, Hermanson, Daniel J., Banerjee, Surajit, Ghebreselasie, Kebreab, Clayton, Gina M., Garavito, R. Michael, Marnett, Lawrence J.
Published in The Journal of biological chemistry (07.03.2014)
Published in The Journal of biological chemistry (07.03.2014)
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Journal Article
Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation
Hermanson, Daniel J, Hartley, Nolan D, Gamble-George, Joyonna, Brown, Naoko, Shonesy, Brian C, Kingsley, Phillip J, Colbran, Roger J, Reese, Jeffrey, Marnett, Lawrence J, Patel, Sachin
Published in Nature neuroscience (01.09.2013)
Published in Nature neuroscience (01.09.2013)
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Journal Article
(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2
Duggan, Kelsey C, Hermanson, Daniel J, Musee, Joel, Prusakiewicz, Jeffery J, Scheib, Jami L, Carter, Bruce D, Banerjee, Surajit, Oates, J A, Marnett, Lawrence J
Published in Nature chemical biology (01.11.2011)
Published in Nature chemical biology (01.11.2011)
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Journal Article
Competition and allostery govern substrate selectivity of cyclooxygenase-2
Mitchener, Michelle M., Hermanson, Daniel J., Shockley, Erin M., Brown, H. Alex, Lindsley, Craig W., Reese, Jeff, Rouzer, Carol A., Lopez, Carlos F., Marnett, Lawrence J.
Published in Proceedings of the National Academy of Sciences - PNAS (06.10.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (06.10.2015)
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Journal Article
Chemical Proteomics Identifies SLC25A20 as a Functional Target of the Ingenol Class of Actinic Keratosis Drugs
Parker, Christopher G, Kuttruff, Christian A, Galmozzi, Andrea, Jørgensen, Lars, Yeh, Chien-Hung, Hermanson, Daniel J, Wang, Yujia, Artola, Marta, McKerrall, Steven J, Josyln, Christopher M, Nørremark, Bjarne, Dünstl, Georg, Felding, Jakob, Saez, Enrique, Baran, Phil S, Cravatt, Benjamin F
Published in ACS central science (27.12.2017)
Published in ACS central science (27.12.2017)
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Journal Article
Corticotropin-releasing hormone drives anandamide hydrolysis in the amygdala to promote anxiety
Gray, J Megan, Vecchiarelli, Haley A, Morena, Maria, Lee, Tiffany T Y, Hermanson, Daniel J, Kim, Alexander B, McLaughlin, Ryan J, Hassan, Kowther I, Kühne, Claudia, Wotjak, Carsten T, Deussing, Jan M, Patel, Sachin, Hill, Matthew N
Published in The Journal of neuroscience (04.03.2015)
Published in The Journal of neuroscience (04.03.2015)
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Journal Article
386 Endocannabinoid-Mediated Effects of Substrate-Selective COX-2 Inhibitors on Gastrointestinal Motility in the Mouse
Bashashati, Mohammad, Keenan, Catherine M, Burkhardt, Wiebke, Hermanson, Daniel J, Kingsley, Philip J, Patel, Sachin, Marnett, Lawrence, Sharkey, Keith A
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2015)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2015)
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Journal Article
Substrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen Probes
Windsor, Matthew A, Hermanson, Daniel J, Kingsley, Philip J, Xu, Shu, Crews, Brenda C, Ho, Winnie, Keenan, Catherine M, Banerjee, Surajit, Sharkey, Keith A, Marnett, Lawrence J
Published in ACS medicinal chemistry letters (13.09.2012)
Published in ACS medicinal chemistry letters (13.09.2012)
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Journal Article
Ultra-Fast Multi-Organ Proteomics Unveils Tissue-Specific Mechanisms of Drug Efficacy and Toxicity
Xiong, Yun, Tan, Lin, Chan, Wai-Kin, Yin, Eric S, Donepudi, Sri Ramya, Ding, Jibin, Wei, Bo, Tran, Bao, Martinez, Sara, Mahmud, Iqbal, Stewart, Hamish I, Hermanson, Daniel J, Weinstein, John N, Lorenzi, Philip L
Published in bioRxiv (05.10.2024)
Published in bioRxiv (05.10.2024)
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Journal Article
SUBSTRATE-SELECTIVE INHIBITION OF ENDOCANNABINOID OXYGENATION
MARNETT, LAWRENCE, J, WINDSOR, MATTHEW, A, PATEL, SACHIN, HERMANSON, DANIEL, J
Year of Publication 16.07.2015
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Year of Publication 16.07.2015
Patent
COMPOSITIONS AND METHODS FOR SUBSTRATE-SELECTIVE INHIBITION OF ENDOCANNABINOID OXYGENATION
MARNETT, LAWRENCE, J, WINDSOR, MATTHEW, A, PATEL, SACHIN, HERMANSON, DANIEL, J
Year of Publication 23.01.2014
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Year of Publication 23.01.2014
Patent