Characterization of tau binding by gosuranemab
Sopko, Richelle, Golonzhka, Olga, Arndt, Joseph, Quan, Chao, Czerkowicz, Julie, Cameron, Andrew, Smith, Benjamin, Murugesan, Yogapriya, Gibbons, Garrett, Kim, Soo-Jung, Trojanowski, John Q., Lee, Virginia M.Y., Brunden, Kurt R., Graham, Danielle L., Weinreb, Paul H., Hering, Heike
Published in Neurobiology of disease (01.12.2020)
Published in Neurobiology of disease (01.12.2020)
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TANGO: a placebo-controlled randomized phase 2 study of efficacy and safety of the anti-tau monoclonal antibody gosuranemab in early Alzheimer's disease
Shulman, Melanie, Kong, Jessica, O'Gorman, John, Ratti, Elena, Rajagovindan, Rajasimhan, Viollet, Louis, Huang, Ellen, Sharma, Sanjiv, Racine, Annie M, Czerkowicz, Julie, Graham, Danielle, Li, Yumeng, Hering, Heike, Haeberlein, Samantha Budd
Published in Nature aging (01.12.2023)
Published in Nature aging (01.12.2023)
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Antisense Oligonucleotide-Mediated Reduction of HDAC6 Does Not Reduce Tau Pathology in P301S Tau Transgenic Mice
Valencia, Antonio, Bieber, Veronica L. Reinhart, Bajrami, Bekim, Marsh, Galina, Hamann, Stefan, Wei, Ru, Ling, Karen, Rigo, Frank, Arnold, H. Moore, Golonzhka, Olga, Hering, Heike
Published in Frontiers in neurology (28.06.2021)
Published in Frontiers in neurology (28.06.2021)
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Generation and characterization of a rabbit monoclonal antibody site-specific for tau O-GlcNAcylated at serine 400
Cameron, Andrew, Giacomozzi, Brandy, Joyce, John, Gray, Audrey, Graham, Danielle, Ousson, Solenne, Neny, Maud, Beher, Dirk, Carlson, George, O’Moore, Jill, Shearman, Mark, Hering, Heike
Published in FEBS letters (15.11.2013)
Published in FEBS letters (15.11.2013)
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Differential efficacy of the TSPO ligands etifoxine and XBD-173 in two rodent models of Multiple Sclerosis
Ravikumar, Brinda, Crawford, Dan, Dellovade, Tammy, Savinainen, Anneli, Graham, Danielle, Liere, Philippe, Oudinet, Jean-Paul, Webb, Mike, Hering, Heike
Published in Neuropharmacology (01.09.2016)
Published in Neuropharmacology (01.09.2016)
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Increased O-GlcNAcylation reduces pathological tau without affecting its normal phosphorylation in a mouse model of tauopathy
Graham, Danielle L., Gray, Audrey J., Joyce, John A., Yu, Dongzi, O'Moore, Jill, Carlson, George A., Shearman, Mark S., Dellovade, Tammy L., Hering, Heike
Published in Neuropharmacology (01.04.2014)
Published in Neuropharmacology (01.04.2014)
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Progranulin Is a Chemoattractant for Microglia and Stimulates Their Endocytic Activity
Pickford, Fiona, Marcus, Jacob, Camargo, Luiz Miguel, Xiao, Qiurong, Graham, Danielle, Mo, Jan-Rung, Burkhardt, Matthew, Kulkarni, Vinayak, Crispino, Jamie, Hering, Heike, Hutton, Michael
Published in The American journal of pathology (2011)
Published in The American journal of pathology (2011)
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Proteomics studies to investigate alterations in the tau interactome under conditions of elevated cellular O‐GlcNAcylation: Molecular and cell biology/tau
Choi, Jinkuk, Walther, Dirk M., Bajrami, Bekim, Halftermeyer, Anais, Rajamohamed Sait, Hameetha Banu, Okugawa, Naomi, Engle, Sandra J., Wei, Ru, Hering, Heike
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Proteomics studies to investigate alterations in the tau interactome under conditions of elevated cellular O‐GlcNAcylation
Choi, Jinkuk, Walther, Dirk M., Bajrami, Bekim, Halftermeyer, Anais, Rajamohamed Sait, Hameetha Banu, Okugawa, Naomi, Engle, Sandra J., Wei, Ru, Hering, Heike
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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P4‐021: ANTI‐TAU ANTIBODY BIIB092 BINDS SECRETED TAU IN PRECLINICAL MODELS AND ALZHEIMER'S DISEASE CEREBROSPINAL FLUID
Czerkowicz, Julie, Chen, Weiping, Cameron, Andrew, Sopko, Richelle, Weinreb, Paul, Hering, Heike, Graham, Danielle
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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BIIB092 DOES NOT INTERFERE WITH RADIOLABELED MK6240 BINDING TO NEUROFIBRILLARY TANGLES: RESULTS FROM IN VITRO COMPETITION BINDING STUDY IN ALZHEIMER’S BRAIN TISSUE SECTIONS
Girmay, Sara, Garros, Roser Farre, Yadav, Abha, Sopko, Richelle, Hering, Heike, Weinreb, Paul, Salem, Nicolas, Wells, Lisa, Rajagovindan, Raj
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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P1‐377: BIIB092 DOES NOT INTERFERE WITH RADIOLABELED MK6240 BINDING TO NEUROFIBRILLARY TANGLES: RESULTS FROM IN VITRO COMPETITION BINDING STUDY IN ALZHEIMER'S BRAIN TISSUE SECTIONS
Girmay, Sara, Garros, Roser Farre, Yadav, Abha, Sopko, Richelle, Hering, Heike, Weinreb, Paul, Salem, Nicolas, Wells, Lisa, Rajagovindan, Raj
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain
Cook, Brendon E, Nag, Sangram, Arakawa, Ryosuke, Lin, Edward Yin-Shiang, Stratman, Nancy, Guckian, Kevin, Hering, Heike, Lulla, Mukesh, Choi, Jinkuk, Salinas, Cristian, Genung, Nathan E, Morén, Anton Forsberg, Bolin, Martin, Boscutti, Giulia, Plisson, Christophe, Martarello, Laurent, Halldin, Christer, Kaliszczak, Maciej A
Published in Journal of Nuclear Medicine (01.10.2023)
Published in Journal of Nuclear Medicine (01.10.2023)
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Development of a Novel [11C]CO-Labeled Positron Emission Tomography Radioligand [11C]BIO-1819578 for the Detection of O‑GlcNAcase Enzyme Activity
Nag, Sangram, Bolin, Martin, Datta, Prodip, Arakawa, Ryosuke, Forsberg Morén, Anton, Khani Maynaq, Yasir, Lin, Edward, Genung, Nathan, Hering, Heike, Guckian, Kevin, Martarello, Laurent, Kaliszczak, Maciej, Halldin, Christer
Published in ACS chemical neuroscience (19.07.2023)
Published in ACS chemical neuroscience (19.07.2023)
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P4‐058: A NOVEL TRANSGENIC RAT MODEL THAT PRESENTS PATHOPHYSIOLOGICAL LEVELS OF HUMAN TAU IN CSF, AXONOPATHY, HIPPOCAMPAL NETWORK DISRUPTION, AND COGNITIVE DEFICITS
Choi, Jinkuk, Czerkowicz, Julie, Craft, Michael, Stoiljkovic, Milan, Leach, Prescott, Bieber, Veronica, Halftermeyer, Anais, Marsh, Galina, Hamann, Stefan, Plowey, Edward, Reynolds, Taylor L., Arnold, Moore, Hajos, Mihaly, Hering, Heike
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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