Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis
Llabani, Evijola, Hicklin, Robert W., Lee, Hyang Yeon, Motika, Stephen E., Crawford, Lisa A., Weerapana, Eranthie, Hergenrother, Paul J.
Published in Nature chemistry (01.06.2019)
Published in Nature chemistry (01.06.2019)
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Enantioselective Synthesis of Isocarbostyril Alkaloids and Analogs Using Catalytic Dearomative Functionalization of Benzene
Bingham, Tanner W, Hernandez, Lucas W, Olson, Daniel G, Svec, Riley L, Hergenrother, Paul J, Sarlah, David
Published in Journal of the American Chemical Society (09.01.2019)
Published in Journal of the American Chemical Society (09.01.2019)
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Journal Article
A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products
Huigens, 3rd, Robert W, Morrison, Karen C, Hicklin, Robert W, Flood, Jr, Timothy A, Richter, Michelle F, Hergenrother, Paul J
Published in Nature chemistry (01.03.2013)
Published in Nature chemistry (01.03.2013)
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Journal Article
The Complex Role of the Triphenylmethyl Motif in Anticancer Compounds
Palchaudhuri, Rahul, Nesterenko, Vitaliy, Hergenrother, Paul J
Published in Journal of the American Chemical Society (06.08.2008)
Published in Journal of the American Chemical Society (06.08.2008)
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Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane
González-López, Adrián, Larsson, Daniel S D, Koripella, Ravi Kiran, Cain, Brett N, Chavez, Martin Garcia, Hergenrother, Paul J, Sanyal, Suparna, Selmer, Maria
Published in Scientific reports (20.06.2024)
Published in Scientific reports (20.06.2024)
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Phase I study of procaspase-activating compound-1 (PAC-1) in the treatment of advanced malignancies
Danciu, Oana C, Holdhoff, Matthias, Peterson, Richard A, Fischer, James H, Liu, Li C, Wang, Heng, Venepalli, Neeta K, Chowdhery, Rozina, Nicholas, M Kelly, Russell, Meredith J, Fan, Timothy M, Hergenrother, Paul J, Tarasow, Theodore M, Dudek, Arkadiusz Z
Published in British journal of cancer (23.03.2023)
Published in British journal of cancer (23.03.2023)
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Synthesis and Anticancer Activity of All Known (−)-Agelastatin Alkaloids
Han, Sunkyu, Siegel, Dustin S, Morrison, Karen C, Hergenrother, Paul J, Movassaghi, Mohammad
Published in Journal of organic chemistry (06.12.2013)
Published in Journal of organic chemistry (06.12.2013)
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Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells
Granchi, Carlotta, Roy, Sarabindu, Giacomelli, Chiara, Macchia, Marco, Tuccinardi, Tiziano, Martinelli, Adriano, Lanza, Mario, Betti, Laura, Giannaccini, Gino, Lucacchini, Antonio, Funel, Nicola, León, Leticia G, Giovannetti, Elisa, Peters, Godefridus J, Palchaudhuri, Rahul, Calvaresi, Emilia C, Hergenrother, Paul J, Minutolo, Filippo
Published in Journal of medicinal chemistry (24.03.2011)
Published in Journal of medicinal chemistry (24.03.2011)
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