Oral topotecan: bioavailability and effect of food co-administration
HERBEN, V. M. M, ROSING, H, TEN BOKKEL HUININK, W. W, VAN ZOMEREN, D. M, BATCHELOR, D, DOYLE, E, BEUSENBERG, F. D, BEIJNEN, J. H, SCHELLENS, J. H. M
Published in British Journal of Cancer (01.07.1999)
Published in British Journal of Cancer (01.07.1999)
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Isolation and structural confirmation of N-desmethyl topotecan, a metabolite of topotecan
ROSING, H, HERBEN, V. M. M, VAN GORTEL-VAN ZOMEREN, D. M, HOP, E, KETTENES-VAN DEN BOSCH, J. J, TEN BOKKEL HUININK, W. W, BEIJNEN, J. H
Published in Cancer chemotherapy and pharmacology (28.02.1997)
Published in Cancer chemotherapy and pharmacology (28.02.1997)
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Journal Article
Clinical pharmacokinetics of topotecan
Herben, V M, ten Bokkel Huinink, W W, Beijnen, J H
Published in Clinical pharmacokinetics (01.08.1996)
Published in Clinical pharmacokinetics (01.08.1996)
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Journal Article
Phase I and Pharmacokinetic Study of Irinotecan Administered as a Low-Dose, Continuous Intravenous Infusion Over 14 Days in Patients With Malignant Solid Tumors
HERBEN, V. M. M, SCHELLENS, J. H. M, SWART, M, GRUIA, G, VERNILLET, L, BEIJNEN, J. H, TEN BOKKEL HUININK, W. W
Published in Journal of clinical oncology (01.06.1999)
Published in Journal of clinical oncology (01.06.1999)
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Journal Article
Sensitive Determination of the Carboxylate and Lactone Forms of the Novel Antitumor Drug Irinotecan and Its Active Metabolite in Plasma by HPLC
Herben, V. M. M., Mazee, D., van Gortel-van Zomeren, D. M., Zeedijk, S., Rosing, H., Schellens, J. H. M., ten Bokkel Huinink, W. W., Beijnen, J. H.
Published in Journal of liquid chromatography & related technologies (01.06.1998)
Published in Journal of liquid chromatography & related technologies (01.06.1998)
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Journal Article
Phase I and pharmacokinetic study of the combination of topotecan and ifosfamide administered intravenously every 3 weeks
KERBUSCH, T, GROENEWEGEN, G, BEIJNEN, J. H, SCHELLENS, J. H. M, MATHOT, R. A. A, HERBEN, V. M. M, TEN BOKKEL HUININK, W. W, SWART, M, AMBAUM, B, ROSING, H, JANSEN, S, VOEST, E. E
Published in British journal of cancer (14.06.2004)
Published in British journal of cancer (14.06.2004)
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Journal Article
Phase I and Pharmacologic Study of the Combination of Paclitaxel, Cisplatin, and Topotecan Administered Intravenously Every 21 Days as First-Line Therapy in Patients With Advanced Ovarian Cancer
HERBEN, V. M. M, NANNAN PANDAY, V. R, TEN BOKKEL HUININK, W. W, RICHEL, D. J, SCHELLENS, J. H. M, VAN DER VANGE, N, ROSING, H, BEUSENBERG, F. D, HEARN, S, DOYLE, E, BEIJNEN, J. H
Published in Journal of clinical oncology (01.03.1999)
Published in Journal of clinical oncology (01.03.1999)
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Journal Article
Phase I and Pharmacokinetic Study of a Daily Times 5 Short Intravenous Infusion Schedule of 9-Aminocamptothecin in a Colloidal Dispersion Formulation in Patients With Advanced Solid Tumors
HERBEN, V. M. M, VAN GIJN, R, SCHELLENS, J. H. M, SCHOT, M, LIEVERST, J, HILLEBRAND, M. J. X, SCHOEMAKER, N. E, PORRO, M. G, BEIJNEN, J. H, TEN BOKKEL HUININK, W. W
Published in Journal of clinical oncology (01.06.1999)
Published in Journal of clinical oncology (01.06.1999)
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Journal Article
Distribution of ifosfamide and metabolites between plasma and erythrocytes
Kerbusch, T., Herben, V.M.M., Jeuken, M-J.J., Ouwerkerk, J., Keizer, H.J., Beijnen, J.H.
Published in Biopharmaceutics & drug disposition (01.04.2001)
Published in Biopharmaceutics & drug disposition (01.04.2001)
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High-performance liquid chromatographic analysis of the investigational anticancer drug 9-aminocamptothecin, as the lactone form and as the total of the lactone and the hydroxycarboxylate forms, in micro-volumes of human plasma
van Gijn, R., Herben, V.M.M., Hillebrand, M.J.X., ten Bokkel Huinink, W.W., Bult, A., Beijnen, J.H.
Published in Journal of pharmaceutical and biomedical analysis (01.09.1998)
Published in Journal of pharmaceutical and biomedical analysis (01.09.1998)
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Characterization of the pharmacodynamic interaction between parent drug and active metabolite in vivo: midazolam and alpha-OH-midazolam
Tuk, B, van Oostenbruggen, M F, Herben, V M, Mandema, J W, Danhof, M
Published in The Journal of pharmacology and experimental therapeutics (01.05.1999)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.1999)
Journal Article
Oral topotecan: bioavailablity and effect of food co-administration
Herben, V M, Rosing, H, ten Bokkel Huinink, W W, van Zomeren, D M, Batchelor, D, Doyle, E, Beusenberg, F D, Beijnen, J H, Schellens, J H
Published in British journal of cancer (01.07.1999)
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Published in British journal of cancer (01.07.1999)
Journal Article
Characterization of the Pharmacodynamic Interaction between Parent Drug and Active Metabolite In Vivo: Midazolam and α-OH-Midazolam
B. Tuk, M. F. van Oostenbruggen, V. M. M. Herben, J. W. Mandema, M. Danhof
Published in The Journal of pharmacology and experimental therapeutics (01.05.1999)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.1999)
Journal Article
Clinical pharmacokinetics of camptothecin topoisomerase I inhibitors
Herben, V M, Ten Bokkel Huinink, W W, Schellens, J H, Beijnen, J H
Published in Pharmacy world and science (01.08.1998)
Published in Pharmacy world and science (01.08.1998)
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