MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T cell treatment of solid tumors
Kinkhabwala, Ali, Herbel, Christoph, Pankratz, Jennifer, Yushchenko, Dmytro A., Rüberg, Silvia, Praveen, Paurush, Reiß, Sandy, Rodriguez, Federico Carlos, Schäfer, Daniel, Kollet, Jutta, Dittmer, Vera, Martinez-Osuna, Manuel, Minnerup, Lara, Reinhard, Claudia, Dzionek, Andrzej, Rockel, Thomas Dino, Borbe, Stefan, Büscher, Martin, Krieg, Jürgen, Nederlof, Michel, Jungblut, Melanie, Eckardt, Dominik, Hardt, Olaf, Dose, Christian, Schumann, Eik, Peters, Ralf-Peter, Miltenyi, Stefan, Schmitz, Jürgen, Müller, Werner, Bosio, Andreas
Published in Scientific reports (03.02.2022)
Published in Scientific reports (03.02.2022)
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Identification of CD318, TSPAN8 and CD66c as target candidates for CAR T cell based immunotherapy of pancreatic adenocarcinoma
Schäfer, Daniel, Tomiuk, Stefan, Küster, Laura N., Rawashdeh, Wa’el Al, Henze, Janina, Tischler-Höhle, German, Agorku, David J., Brauner, Janina, Linnartz, Cathrin, Lock, Dominik, Kaiser, Andrew, Herbel, Christoph, Eckardt, Dominik, Lamorte, Melina, Lenhard, Dorothee, Schüler, Julia, Ströbel, Philipp, Missbach-Guentner, Jeannine, Pinkert-Leetsch, Diana, Alves, Frauke, Bosio, Andreas, Hardt, Olaf
Published in Nature communications (05.03.2021)
Published in Nature communications (05.03.2021)
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Journal Article
WWOX, the common fragile site FRA16D gene product, regulates ATM activation and the DNA damage response
Abu-Odeh, Mohammad, Salah, Zaidoun, Herbel, Christoph, Hofmann, Thomas G., Aqeilan, Rami I.
Published in Proceedings of the National Academy of Sciences - PNAS (04.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (04.11.2014)
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Journal Article
Targeting Stage-Specific Embryonic Antigen 4 (SSEA-4) in Triple Negative Breast Cancer by CAR T Cells Results in Unexpected on Target/off Tumor Toxicities in Mice
Pfeifer, Rita, Al Rawashdeh, Wa'el, Brauner, Janina, Martinez-Osuna, Manuel, Lock, Dominik, Herbel, Christoph, Eckardt, Dominik, Assenmacher, Mario, Bosio, Andreas, Hardt, Olaf T, Johnston, Ian C D
Published in International journal of molecular sciences (24.05.2023)
Published in International journal of molecular sciences (24.05.2023)
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Journal Article
CRISPR-Mediated Editing of the B Cell Receptor in Primary Human B Cells
Greiner, Vera, Bou Puerto, Regina, Liu, Suying, Herbel, Christoph, Carmona, Ellese M, Goldberg, Michael S
Published in iScience (01.02.2019)
Published in iScience (01.02.2019)
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Journal Article
Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death
Bitomsky, Nadja, Conrad, Elisa, Moritz, Christian, Polonio-Vallon, Tilman, Sombroek, Dirk, Schultheiss, Kathrin, Glas, Carolina, Greiner, Vera, Herbel, Christoph, Mantovani, Fiamma, del Sal, Giannino, Peri, Francesca, Hofmann, Thomas G
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2013)
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Journal Article
Segmentation strategy for adult cardiac tissue imaging analysis using MACs iQ view software
Albert, Alba M., Appelshoffer, Anijutta, Rüberg, Silvia, El Yassouri, Fabio, Praveen, Paurush, Herbel, Christoph, Eckardt, Dominik
Published in Journal of molecular and cellular cardiology (31.12.2022)
Published in Journal of molecular and cellular cardiology (31.12.2022)
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Journal Article
Abstract 13973: Human iPSC-Derived Multi-Cell-Type Engineered Heart Tissues as an in vitro Model to Study Pathological Cardiac Hypertrophy
Wrona, Kinga M, Albert, Alba M. M, Eckardt, Dominik, Herbel, Christoph, Krause, Julia, Starbatty, Jutta, Hemkemeyer, Sandra A A, Frye, Maike, Cuello, Friederike, Eschenhagen, Thomas, Hirt, Marc N
Published in Circulation (New York, N.Y.) (08.11.2022)
Published in Circulation (New York, N.Y.) (08.11.2022)
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Prostaglandin E2 Alters the Differentiation and Function of Antigen-Specific T Cells By Targeting the Metabolic Gene Regulatory Network Downstream of mTORC1
Herbel, Christoph, Patsoukis, Nikolaos, Weaver, Jessica D, Boussiotis, Vassiliki A.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Clinical significance of T cell metabolic reprogramming in cancer
Herbel, Christoph, Patsoukis, Nikolaos, Bardhan, Kankana, Seth, Pankaj, Weaver, Jessica D., Boussiotis, Vassiliki A.
Published in Clinical and Translational Medicine (01.12.2016)
Published in Clinical and Translational Medicine (01.12.2016)
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Book Review
Preclinical Evaluation of Novel Folate Receptor 1-Directed CAR T Cells for Ovarian Cancer
Daigre, Julie, Martinez-Osuna, Manuel, Bethke, Maria, Steiner, Larissa, Dittmer, Vera, Krischer, Katrin, Bleilevens, Cathrin, Brauner, Janina, Kopatz, Jens, Grundmann, Matthias David, Praveen, Paurush, Eckardt, Dominik, Bosio, Andreas, Herbel, Christoph
Published in Cancers (01.01.2024)
Published in Cancers (01.01.2024)
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Abstract 4694: Evaluation of tumor-associated antigen expression with the MACSimaTM high-content imaging platform
Herbel, Christoph, Dittmer, Vera, Martinez-Osuna, Manuel, Kuester, Laura Nadine, Schaefer, Daniel, Drewes, Jan, Kollet, Jutta, Mueller, Werner, Mallmann, Michael, Mallmann, Peter, Stroebel, Philipp, Hardt, Olaf, Eckardt, Dominik, Bosio, Andreas
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 3189: Pre-clinical evaluation of novel folate receptor 1 directed CAR T cells for high grade serous ovarian cancer
Herbel, Christoph, Daigre, Julie, Martinez-Osuna, Manuel, Bethke, Maria, Steiner, Larissa, Brauner, Janina, Kopatz, Jens, Praveen, Paurush, Eckardt, Dominik, Bosio, Andreas
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 2813: Identification of a novel tumor marker combination THY1-EPCAM for adaptor CAR T cell therapy in ovarian cancer
Herbel, Christoph, Dittmer, Vera, Martinez-Osuna, Manuel, Reiß, Sandy, Mallmann, Peter, Ratiu, Dominik, Mallmann, Michael, Praveen, Paurush, Müller, Werner, Eckardt, Dominik, Bosio, Andreas
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death
Bitomsky, Nadja, Conrad, Elisa, Moritz, Christian, Polonio-Vallon, Tilman, Sombroek, Dirk, Schultheiss, Kathrin, Glas, Carolina, Greiner, Vera, Herbel, Christoph, Mantovani, Fiamma, del Sal, Giannino, Peri, Francesca, Hofmann, Thomas G.
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2013)
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Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2013)
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