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Affibody-based nanoprobes for HER2-expressing cell and tumor imaging
Gao, Jinhao, Chen, Kai, Miao, Zheng, Ren, Gang, Chen, Xiaoyuan, Gambhir, Sanjiv S., Cheng, Zhen
Published in Biomaterials (01.03.2011)
Published in Biomaterials (01.03.2011)
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330PPharmacokinetics (PK), safety, and efficacy of [fam-] trastuzumab deruxtecan with OATP1B/CYP3A inhibitors in subjects with HER2-expressing advanced solid tumours
Bang, Y-J, Karayama, M, Takahashi, M, Watanabe, J, Minami, H, Yamamoto, N, Kinoshita, I, Lin, C -C, Im, Y -H, Fujiki, T, Achiwa, I, Kamiyama, E, Okuda, Y, Lee, C, Takahashi, S
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Pharmacokinetics (PK), safety, and efficacy of [fam-] trastuzumab deruxtecan with OATP1B/CYP3A inhibitors in subjects with HER2-expressing advanced solid tumours
Bang, Y.-J., Karayama, M., Takahashi, M., Watanabe, J., Minami, H., Yamamoto, N., Kinoshita, I., Lin, C.-C., Im, Y.-H., Fujiki, T., Achiwa, I., Kamiyama, E., Okuda, Y., Lee, C., Takahashi, S.
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Phase I study of A166 in patients with HER2-expressing locally advanced or metastatic solid tumors
Hu, Xichun, Zhang, Jian, Liu, Rujiao, Gao, Shuiping, Qing, Yan, Yi, Shuli, Yuan, Juanjuan, Chen, Hong, Fan, Bin, Zheng, Haochuan, Wang, Jingyi
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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A phase II, multicenter, open-label study of [fam-] trastuzumab deruxtecan (DS-8201a) in subjects with HER2-expressing gastric cancer
Shitara, Kohei, Bang, Yung-Jue, Chung, Hyun Cheol, Yabusaki, Hiroshi, Iwasa, Satoru, Sakai, Daisuke, Muro, Kei, Sugimoto, Naotoshi, Yasui, Hisateru, Gamoh, Makio, Murakawa, Yasuko, Negoro, Yuji, Nishina, Tomohiro, Hosaka, Hisashi, Omuro, Yasushi, Kawaguchi, Yoshinori, Sugihara, Masahiro, Saito, Kaku, Dalal, Rita, Yamaguchi, Kensei
Published in Journal of clinical oncology (01.02.2019)
Published in Journal of clinical oncology (01.02.2019)
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Updated results of phase 1 study of DS-8201a in subjects with HER2-expressing gastric cancer
Iwasa, Satoru, Shitara, Kohei, Takahashi, Shunji, Park, Haeseong, Kadowaki, Shigenori, Modi, Shanu, Nonagase, Yoshikane, Tamura, Kenji, Yamaguchi, Kensei, Muro, Kei, Tsurutani, Junji, Shahidi, Javad, Lee, Caleb C., Sugihara, Masahiro, Kawaguchi, Yoshinori, Doi, Toshihiko
Published in Journal of clinical oncology (01.02.2018)
Published in Journal of clinical oncology (01.02.2018)
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Preliminary results of a phase I, first-in-human, dose escalation study of IMM2902 in patients with HER2-expressing advanced solid tumors
Zhang, Jian, Zhao, Chuanhua, Cheng, Ying, Zhu, Liming, Song, Zhengbo, Xu, Nong, Wang, Zhen, Wang, Yanping, Du, Yiqun, Jing, Deqiang, Chen, Dinglu, Qu, Qiaofeng, Zhao, Xiwen, Li, Wei, Lu, Qiying, Tian, Wenzhi, Xu, Jianming
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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208TiPA randomized, phase II, multicenter, open-label study of trastuzumab deruxtecan (DS-8201a) in subjects with HER2-expressing gastric cancer
Shitara, K, Bang, Y-J, Sakai, D, Yasui, H, Kawaguchi, Y, Sugihara, M, Saito, K, Dalal, R, Yamaguchi, K
Published in Annals of oncology (01.11.2018)
Published in Annals of oncology (01.11.2018)
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A randomized, phase II, multicenter, open-label study of trastuzumab deruxtecan (DS-8201a) in subjects with HER2-expressing gastric cancer
Shitara, K., Bang, Y.-J., Sakai, D., Yasui, H., Kawaguchi, Y., Sugihara, M., Saito, K., Dalal, R., Yamaguchi, K.
Published in Annals of oncology (01.11.2018)
Published in Annals of oncology (01.11.2018)
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330P - Pharmacokinetics (PK), safety, and efficacy of [fam-] trastuzumab deruxtecan with OATP1B/CYP3A inhibitors in subjects with HER2-expressing advanced solid tumours
Bang, Y.-J., Karayama, M., Takahashi, M., Watanabe, J., Minami, H., Yamamoto, N., Kinoshita, I., Lin, C.-C., Im, Y.-H., Fujiki, T., Achiwa, I., Kamiyama, E., Okuda, Y., Lee, C., Takahashi, S.
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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A multicenter, multicohort, phase 2 study of trastuzumab deruxtecan (DS-8201a) in subjects with HER2-expressing metastatic colorectal cancer - Trial in progress
Yoshino, T., Siena, S., Dalal, R., Okuda, Y., Yamamoto, E., Grothey, A.
Published in Annals of oncology (01.06.2018)
Published in Annals of oncology (01.06.2018)
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A randomized phase 2, multicenter, open-label study of trastuzumab deruxtecan (DS-8201a) in subjects with HER2-expressing gastric cancer
Yamaguchi, Kensei, Bang, Yung-Jue, Sakai, Daisuke, Yasui, Hisateru, Kawaguchi, Yoshinori, Sugihara, Masahiro, Saito, Kaku, Dalal, Rita, Shitara, Kohei
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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P-295A multicenter, multicohort, phase 2 study of trastuzumab deruxtecan (DS-8201a) in subjects with HER2-expressing metastatic colorectal cancer - Trial in progress
Yoshino, T, Siena, S, Dalal, R, Okuda, Y, Yamamoto, E, Grothey, A
Published in Annals of oncology (01.06.2018)
Published in Annals of oncology (01.06.2018)
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Abstract P1-18-12: A phase 1, multicenter, open-label study to assess the effect of [fam-] trastuzumab deruxtecan (T-DXd; DS-8201a) on QTc and pharmacokinetics in subjects with HER2-expressing metastatic and/or unresectable breast cancer
Yamashita, Toshinari, Shimomura, Akihiko, Takano, Toshimi, Sagara, Yasuaki, Watanabe, Junichiro, Tokunaga, Eriko, Kikumori, Kunika, Kamiyama, Emi, Kamio, Takahiro, Nakamura, Ryo, Shinkai, Tetsu, Takahashi, Shunji
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Trastuzumab deruxtecan (DS-8201a) in subjects with HER2-expressing solid tumors: Long-term results of a large phase 1 study with multiple expansion cohorts
Iwata, Hiroji, Tamura, Kenji, Doi, Toshihiko, Tsurutani, Junji, Modi, Shanu, Park, Haeseong, Krop, Ian E., Sagara, Yasuaki, Redfern, Charles H., Murthy, Rashmi Krishna, Redman, Rebecca A., Shitara, Kohei, Fujisaki, Yoshihiko, Sugihara, Masahiro, Zhang, Lin, Shahidi, Javad, Yver, Antoine, Takahashi, Shunji
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Abstract CT098: Phase I study of GQ1005, a new generation HER2-ADC, in patients with HER2-expressing and HER2 mutated advanced solid tumors
Zhou, Caicun, Yang, Bo, Deng, Ting, Wang, Biyun, Zhang, Jian, Sun, Yuping, Wang, Linlin, Yang, Hongwei, Wang, Jingfen, Li, Wei, Song, Qi, Yang, Yuchong
Published in Cancer research (Chicago, Ill.) (05.04.2024)
Published in Cancer research (Chicago, Ill.) (05.04.2024)
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Pharmacokinetics (PK), safety, and efficacy of [fam-] trastuzumab deruxtecan with OATP1B/CYP3A inhibitors in subjects with HER2-expressing advanced solid tumours
Issei Achiwa, Hironobu Minami, Masato Takahashi, J. Watanabe, Yunjoo Im, Yasuyuki Okuda, Ichiro Kinoshita, Noboru Yamamoto, Emi Kamiyama, Satoshi Takahashi, T. Fujiki, Caleb Lee, Y.-J. Bang, C-C. Lin, Masato Karayama
Published in Annals of Oncology (01.10.2019)
Published in Annals of Oncology (01.10.2019)
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317 A phase 1/1b study of SBT6050, a HER2-directed monoclonal antibody conjugated to a toll-like receptor 8 agonist, in subjects with advanced HER2-expressing solid tumors
Emens, Leisha, Beeram, Muralidhar, Hamilton, Erika, Piha-Paul, Sarina, Odegard, Valerie, Hamke, Sue, Hunder, Naomi, Klempner, Samuel
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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