Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors
Ho, Koc-Kan, Parnell, K. Mark, Yuan, Yi, Xu, Yong, Kultgen, Steven G, Hamblin, Steven, Hendrickson, Thomas F, Luo, Bai, Foulks, Jason M, McCullar, Michael V, Kanner, Steven B
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Published in Bioorganic & medicinal chemistry letters (15.01.2013)
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Epigenetic drug discovery: targeting DNA methyltransferases
Foulks, Jason M, Parnell, K Mark, Nix, Rebecca N, Chau, Suzanna, Swierczek, Krzysztof, Saunders, Michael, Wright, Kevin, Hendrickson, Thomas F, Ho, Koc-Kan, McCullar, Michael V, Kanner, Steven B
Published in Journal of biomolecular screening (01.01.2012)
Published in Journal of biomolecular screening (01.01.2012)
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Discovery of 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide activators of the M2 isoform of pyruvate kinase (PKM2)
Xu, Yong, Liu, Xiao-Hui, Saunders, Michael, Pearce, Scott, Foulks, Jason M., Parnell, K. Mark, Clifford, Adrianne, Nix, Rebecca N., Bullough, Jeremy, Hendrickson, Thomas F., Wright, Kevin, McCullar, Michael V., Kanner, Steven B., Ho, Koc-Kan
Published in Bioorganic & medicinal chemistry letters (15.01.2014)
Published in Bioorganic & medicinal chemistry letters (15.01.2014)
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Electrostatic contributions to solvation energies: comparison of free energy perturbation and continuum calculations
Jean-Charles, Arald, Nicholls, Anthony, Sharp, Kim, Honig, Barry, Tempczyk, Anna, Hendrickson, Thomas F, Still, W. Clark
Published in Journal of the American Chemical Society (01.02.1991)
Published in Journal of the American Chemical Society (01.02.1991)
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Identification and structure–activity relationship of 2-morpholino 6-(3-hydroxyphenyl) pyrimidines, a class of potent and selective PI3 kinase inhibitors
Pecchi, Sabina, Renhowe, Paul A., Taylor, Clarke, Kaufman, Susan, Merritt, Hanne, Wiesmann, Marion, Shoemaker, Kevin R., Knapp, Mark S., Ornelas, Elizabeth, Hendrickson, Thomas F., Fantl, Wendy, Voliva, Charles F.
Published in Bioorganic & medicinal chemistry letters (01.12.2010)
Published in Bioorganic & medicinal chemistry letters (01.12.2010)
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 6. Structure−Activity Studies of Orally Bioavailable, 2-Pyridone-Containing Peptidomimetics
Dragovich, Peter S, Prins, Thomas J, Zhou, Ru, Brown, Edward L, Maldonado, Fausto C, Fuhrman, Shella A, Zalman, Leora S, Tuntland, Tove, Lee, Caroline A, Patick, Amy K, Matthews, David A, Hendrickson, Thomas F, Kosa, Maha B, Liu, Bo, Batugo, Minerva R, Gleeson, Jean-Paul R, Sakata, Sylvie K, Chen, Lijian, Guzman, Mark C, Meador, James W, Ferre, Rose Ann, Worland, Stephen T
Published in Journal of medicinal chemistry (11.04.2002)
Published in Journal of medicinal chemistry (11.04.2002)
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Design, Synthesis, and Evaluation of Nonpeptidic Inhibitors of Human Rhinovirus 3C Protease
Webber, Stephen E., Tikhe, Jayashree, Worland, Stephen T., Fuhrman, Shella A., Hendrickson, Thomas F., Matthews, David A., Love, Robert A., Patick, Amy K., Meador, James W., Ferre, Rose Ann, Brown, Edward L., DeLisle, Dorothy M., Ford, Clifford E., Binford, Susan L.
Published in Journal of medicinal chemistry (20.12.1996)
Published in Journal of medicinal chemistry (20.12.1996)
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Structure-Based Design of a Parallel Synthetic Array Directed Toward the Discovery of Irreversible Inhibitors of Human Rhinovirus 3C Protease
Johnson, Theodore O, Hua, Ye, Luu, Hiep T, Brown, Edward L, Chan, Fora, Chu, Shao Song, Dragovich, Peter S, Eastman, Brian W, Ferre, Rose Ann, Fuhrman, Shella A, Hendrickson, Thomas F, Maldonado, Fausto C, Matthews, David A, Meador, James W, Patick, Amy K, Reich, Siegfried H, Skalitzky, Donald J, Worland, Stephen T, Yang, Michelle, Zalman, Leora S
Published in Journal of medicinal chemistry (09.05.2002)
Published in Journal of medicinal chemistry (09.05.2002)
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Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease: Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P1 Glutamine Isosteric Replacements
Webber, Stephen E, Okano, Koji, Little, Thomas L, Reich, Siegfried H, Xin, Yue, Fuhrman, Shella A, Matthews, David A, Love, Robert A, Hendrickson, Thomas F, Patick, Amy K, Meador, James W, Ferre, Rose Ann, Brown, Edward L, Ford, Clifford E, Binford, Susan L, Worland, Stephen T
Published in Journal of medicinal chemistry (16.07.1998)
Published in Journal of medicinal chemistry (16.07.1998)
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Substituted Benzamide Inhibitors of Human Rhinovirus 3C Protease: Structure-Based Design, Synthesis, and Biological Evaluation
Reich, Siegfried H, Johnson, Theodore, Wallace, Michael B, Kephart, Susan E, Fuhrman, Shella A, Worland, Stephen T, Matthews, David A, Hendrickson, Thomas F, Chan, Fora, Meador, James, Ferre, Rose Ann, Brown, Edward L, DeLisle, Dorothy M, Patick, Amy K, Binford, Susan L, Ford, Clifford E
Published in Journal of medicinal chemistry (04.05.2000)
Published in Journal of medicinal chemistry (04.05.2000)
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Esterolytic chemistry of vesicular thiocholine surfactant
Moss, Robert A, Hendrickson, Thomas F, Bizzigotti, George O
Published in Journal of the American Chemical Society (01.09.1986)
Published in Journal of the American Chemical Society (01.09.1986)
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Synthesis, conformational analysis, and antimalarial activity of tricyclic analogs of artemisinin
Avery, Mitchell A, Gao, Fenglan, Chong, Wesley K.M, Hendrickson, Thomas F, Inman, Wayne D, Crews, Phillip
Published in Tetrahedron (24.01.1994)
Published in Tetrahedron (24.01.1994)
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Experimental and computer modeling studies of micellar diastereoselectivity
Moss, Robert A, Hendrickson, Thomas F, Ueoka, Ryuichi, Kim, Kwang Yoo, Weiner, Paul K
Published in Journal of the American Chemical Society (01.07.1987)
Published in Journal of the American Chemical Society (01.07.1987)
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Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 4. Incorporation of P-1 lactam moieties as L-glutamine replacements
Dragovich, PS, Prins, TJ, Zhou, R, Webber, SE, Marakovits, JT, Fuhrman, SA, Patick, AK, Matthews, DA, Lee, CA, Ford, CE, Burke, BJ, Rejto, PA, Hendrickson, TF, Tuntland, T, Brown, EL, Meador, JW, Ferre, RA, Harr, JEV, Kosa, MB, Worland, ST
Published in Journal of medicinal chemistry (08.04.1999)
Published in Journal of medicinal chemistry (08.04.1999)
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Journal Article
Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 4. Incorporation of P1 Lactam Moieties as l-Glutamine Replacements
Dragovich, Peter S, Prins, Thomas J, Zhou, Ru, Webber, Stephen E, Marakovits, Joseph T, Fuhrman, Shella A, Patick, Amy K, Matthews, David A, Lee, Caroline A, Ford, Clifford E, Burke, Benjamin J, Rejto, Paul A, Hendrickson, Thomas F, Tuntland, Tove, Brown, Edward L, Meador, James W, Ferre, Rose Ann, Harr, James E. V, Kosa, Maha B, Worland, Stephen T
Published in Journal of medicinal chemistry (08.04.1999)
Published in Journal of medicinal chemistry (08.04.1999)
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Journal Article
Tripeptide aldehyde inhibitors of human rhinovirus 3C protease: Design, synthesis, biological evaluation, and cocrystal structure solution of P-1 glutamine isosteric replacements
Webber, SE, Okano, K, Little, TL, Reich, SH, Xin, Y, Fuhrman, SA, Matthews, DA, Love, RA, Hendrickson, TF, Patick, AK, Meador, JW, Ferre, RA, Brown, EL, Ford, CE, Binford, SL, Worland, ST
Published in Journal of medicinal chemistry (16.07.1998)
Published in Journal of medicinal chemistry (16.07.1998)
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Interaction of a Novel GDP Exchange Inhibitor with the Ras Protein
Ganguly, Ashit K, Wang, Yu-Sen, Pramanik, Birendra N, Doll, Ronald J, Snow, Mark E, Taveras, Arthur G, Remiszewski, Stacy, Cesarz, David, del Rosario, J, Vibulbhan, Bancha, Brown, Joan E, Kirschmeier, Paul, Huang, Eric C, Heimark, Larry, Tsarbopoulos, Anthony, Girijavallabhan, Viyyoor M, Aust, Robert M, Brown, Edward L, DeLisle, Dorothy M, Fuhrman, Shella A, Hendrickson, Thomas F, Kissinger, Charles R, Love, Robert A, Sisson, Wess A, Villafranca, J. Ernest, Webber, Steve E
Published in Biochemistry (Easton) (10.11.1998)
Published in Biochemistry (Easton) (10.11.1998)
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Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
HUA YE, LUU HIEP THE, EASTMAN BRIAN WALTER, SKALITZKY DONALD JAMES, CHAN FORA P, JOHNSON, JR. THEODORE O, REICH SIEGFRIED HEINZ, YANG YI, CHU SHAO SONG, HENDRICKSON THOMAS F
Year of Publication 24.01.2006
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Year of Publication 24.01.2006
Patent
Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
Hua, Ye, Luu, Hiep The, Chan, Fora P, Johnson, Jr, Theodore O, Reich, Siegfried Heinz, Skalitzky, Donald James, Yang, Yi, Hendrickson, Thomas F, Chu, Shao Song, Eastman, Brian Walter
Year of Publication 24.01.2006
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Year of Publication 24.01.2006
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