TORC2 Signaling Pathway Guarantees Genome Stability in the Face of DNA Strand Breaks
Shimada, Kenji, Filipuzzi, Ireos, Stahl, Michael, Helliwell, Stephen B., Studer, Christian, Hoepfner, Dominic, Seeber, Andrew, Loewith, Robbie, Movva, N. Rao, Gasser, Susan M.
Published in Molecular cell (26.09.2013)
Published in Molecular cell (26.09.2013)
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Journal Article
Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosis
Wang, Zhong-Yi, Keogh, Adrian, Waldt, Annick, Cuttat, Rachel, Neri, Marilisa, Zhu, Shanshan, Schuierer, Sven, Ruchti, Alexandra, Crochemore, Christophe, Knehr, Judith, Bastien, Julie, Ksiazek, Iwona, Sánchez-Taltavull, Daniel, Ge, Hui, Wu, Jing, Roma, Guglielmo, Helliwell, Stephen B., Stroka, Deborah, Nigsch, Florian
Published in Scientific reports (29.09.2021)
Published in Scientific reports (29.09.2021)
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Journal Article
Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy
Potting, Christoph, Crochemore, Christophe, Moretti, Francesca, Nigsch, Florian, Schmidt, Isabel, Manneville, Carole, Carbone, Walter, Knehr, Judith, DeJesus, Rowena, Lindeman, Alicia, Maher, Rob, Russ, Carsten, McAllister, Gregory, Reece-Hoyes, John S., Hoffman, Gregory R., Roma, Guglielmo, Müller, Matthias, Sailer, Andreas W., Helliwell, Stephen B.
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2018)
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Journal Article
Target of rapamycin complex 2–dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae
Bourgoint, Clélia, Rispal, Delphine, Berti, Marina, Filipuzzi, Ireos, Helliwell, Stephen B., Prouteau, Manoël, Loewith, Robbie
Published in The Journal of biological chemistry (03.08.2018)
Published in The Journal of biological chemistry (03.08.2018)
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Journal Article
Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways
Rispal, Delphine, Eltschinger, Sandra, Stahl, Michael, Vaga, Stefania, Bodenmiller, Bernd, Abraham, Yann, Filipuzzi, Ireos, Movva, N.Rao, Aebersold, Ruedi, Helliwell, Stephen B., Loewith, Robbie
Published in The Journal of biological chemistry (12.06.2015)
Published in The Journal of biological chemistry (12.06.2015)
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Journal Article
Evidence for a Functionally Relevant Rocaglamide Binding Site on the eIF4A–RNA Complex
Sadlish, Heather, Galicia-Vazquez, Gabriela, Paris, C. Gregory, Aust, Thomas, Bhullar, Bhupinder, Chang, Lena, Helliwell, Stephen B, Hoepfner, Dominic, Knapp, Britta, Riedl, Ralph, Roggo, Silvio, Schuierer, Sven, Studer, Christian, Porco, John A, Pelletier, Jerry, Movva, N. Rao
Published in ACS chemical biology (19.07.2013)
Published in ACS chemical biology (19.07.2013)
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Journal Article
High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions
Hoepfner, Dominic, Helliwell, Stephen B., Sadlish, Heather, Schuierer, Sven, Filipuzzi, Ireos, Brachat, Sophie, Bhullar, Bhupinder, Plikat, Uwe, Abraham, Yann, Altorfer, Marc, Aust, Thomas, Baeriswyl, Lukas, Cerino, Raffaele, Chang, Lena, Estoppey, David, Eichenberger, Juerg, Frederiksen, Mathias, Hartmann, Nicole, Hohendahl, Annika, Knapp, Britta, Krastel, Philipp, Melin, Nicolas, Nigsch, Florian, Oakeley, Edward J., Petitjean, Virginie, Petersen, Frank, Riedl, Ralph, Schmitt, Esther K., Staedtler, Frank, Studer, Christian, Tallarico, John A., Wetzel, Stefan, Fishman, Mark C., Porter, Jeffrey A., Movva, N. Rao
Published in Microbiological research (01.02.2014)
Published in Microbiological research (01.02.2014)
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Journal Article
Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo
Russell, Oliver M., Fruh, Isabelle, Rai, Pavandeep K., Marcellin, David, Doll, Thierry, Reeve, Amy, Germain, Mitchel, Bastien, Julie, Rygiel, Karolina A., Cerino, Raffaele, Sailer, Andreas W., Lako, Majlinda, Taylor, Robert W., Mueller, Matthias, Lightowlers, Robert N., Turnbull, Doug M., Helliwell, Stephen B.
Published in Scientific reports (29.01.2018)
Published in Scientific reports (29.01.2018)
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Journal Article
High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines
Filipuzzi, Ireos, Cotesta, Simona, Perruccio, Francesca, Knapp, Britta, Fu, Yue, Studer, Christian, Pries, Verena, Riedl, Ralph, Helliwell, Stephen B, Petrovic, Katarina T, Movva, N Rao, Sanglard, Dominique, Tao, Jianshi, Hoepfner, Dominic
Published in PLoS genetics (17.11.2016)
Published in PLoS genetics (17.11.2016)
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Journal Article
Auxin-Inducible Depletion of the Essentialome Suggests Inhibition of TORC1 by Auxins and Inhibition of Vrg4 by SDZ 90-215, a Natural Antifungal Cyclopeptide
Snyder, Nathan A, Kim, Adam, Kester, Louis, Gale, Andrew N, Studer, Christian, Hoepfner, Dominic, Roggo, Silvio, Helliwell, Stephen B, Cunningham, Kyle W
Published in G3 : genes - genomes - genetics (01.03.2019)
Published in G3 : genes - genomes - genetics (01.03.2019)
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Journal Article
An Integrated Approach for Identification and Target Validation of Antifungal Compounds Active against Erg11p
HOEPFNER, Dominic, KARKARE, Shantanu, REINKER, Stefan, FREDERIKSEN, Mathias, RAO MOVVA, N, PORTER, Jeffrey A, RYDER, Neil S, PARKER, Christian N, HELLIWELL, Stephen B, PFEIFER, Martin, TRUNZER, Markus, DE BONNECHOSE, Sophie, ZIMMERLIN, Alfred, TAO, Jianshi, RICHIE, Daryl, HOFMANN, Andreas
Published in Antimicrobial Agents and Chemotherapy (01.08.2012)
Published in Antimicrobial Agents and Chemotherapy (01.08.2012)
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Journal Article
Defining a longevity biotechnology company
Boekstein, Nicola, Barzilai, Nir, Bertram, André, Betts-LaCroix, Joe, Fortney, Kristen, Helliwell, Stephen B., Hufford, Michael, Mannick, Joan, McLaughlin, Jerry, Mellon, Jim, Morgen, Eric, Regge, Nils, Robinton, Daisy A., Sinclair, David A., Young, Sergey, Starr, Risa, Zhavoronkov, Alex, Peyer, James
Published in Nature biotechnology (01.08.2023)
Published in Nature biotechnology (01.08.2023)
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Journal Article
NPR1 Kinase and RSP5-BUL1/2 Ubiquitin Ligase Control GLN3-dependent Transcription in Saccharomyces cerevisiae
Crespo, José L., Helliwell, Stephen B., Wiederkehr, Christa, Demougin, Philippe, Fowler, Brian, Primig, Michael, Hall, Michael N.
Published in The Journal of biological chemistry (03.09.2004)
Published in The Journal of biological chemistry (03.09.2004)
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Journal Article
Stendomycin selectively inhibits TIM23-dependent mitochondrial protein import
Filipuzzi, Ireos, Steffen, Janos, Germain, Mitchel, Goepfert, Laetitia, Conti, Michael A, Potting, Christoph, Cerino, Raffaele, Pfeifer, Martin, Krastel, Philipp, Hoepfner, Dominic, Bastien, Julie, Koehler, Carla M, Helliwell, Stephen B
Published in Nature chemical biology (01.12.2017)
Published in Nature chemical biology (01.12.2017)
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Journal Article
Two low complexity ultra-high throughput methods to identify diverse chemically bioactive molecules using Saccharomyces cerevisiae
Petrovic, Katarina, Pfeifer, Martin, Parker, Christian N., Schuierer, Sven, Tallarico, John, Hoepfner, Dominic, Movva, N. Rao, Scheel, Gunther, Helliwell, Stephen B.
Published in Microbiological research (01.06.2017)
Published in Microbiological research (01.06.2017)
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