Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics
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Published in British journal of pharmacology (01.02.2019)
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Published in Genes & development (15.12.2014)
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The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions
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Published in Nucleic acids research (18.08.2014)
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Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma
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Published in Proceedings of the National Academy of Sciences - PNAS (07.09.2021)
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MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP
Jemth, Ann-Sofie, Gustafsson, Robert, Bräutigam, Lars, Henriksson, Linda, Vallin, Karl S A, Sarno, Antonio, Almlöf, Ingrid, Homan, Evert, Rasti, Azita, Warpman Berglund, Ulrika, Stenmark, Pål, Helleday, Thomas
Published in Nucleic acids research (16.11.2018)
Published in Nucleic acids research (16.11.2018)
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U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden
Glimelius, Bengt, Melin, Beatrice, Enblad, Gunilla, Alafuzoff, Irina, Beskow, Anna, Ahlström, Håkan, Bill-Axelson, Anna, Birgisson, Helgi, Björ, Ove, Edqvist, Per-Henrik, Hansson, Tony, Helleday, Thomas, Hellman, Per, Henriksson, Kerstin, Hesselager, Göran, Hultdin, Magnus, Häggman, Michael, Höglund, Martin, Jonsson, Håkan, Larsson, Chatarina, Lindman, Henrik, Ljuslinder, Ingrid, Mindus, Stephanie, Nygren, Peter, Pontén, Fredrik, Riklund, Katrine, Rosenquist, Richard, Sandin, Fredrik, Schwenk, Jochen M., Stenling, Roger, Stålberg, Karin, Stålberg, Peter, Sundström, Christer, Thellenberg Karlsson, Camilla, Westermark, Bengt, Bergh, Anders, Claesson-Welsh, Lena, Palmqvist, Richard, Sjöblom, Tobias
Published in Acta oncologica (01.02.2018)
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Identification of the MMS22L-TONSL Complex that Promotes Homologous Recombination
Duro, Eris, Lundin, Cecilia, Ask, Katrine, Sanchez-Pulido, Luis, MacArtney, Thomas J., Toth, Rachel, Ponting, Chris P., Groth, Anja, Helleday, Thomas, Rouse, John
Published in Molecular cell (24.11.2010)
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N-Acyl Taurines are Anti-Proliferative in Prostate Cancer Cells
Chatzakos, Vicky, Slätis, Katharina, Djureinovic, Tatjana, Helleday, Thomas, Hunt, Mary C.
Published in Lipids (01.04.2012)
Published in Lipids (01.04.2012)
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Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks
Lundin, Cecilia, North, Matthew, Erixon, Klaus, Walters, Kevin, Jenssen, Dag, Goldman, Alastair S. H., Helleday, Thomas
Published in Nucleic acids research (01.01.2005)
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Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds
Peuget, Sylvain, Zhu, Jiawei, Sanz, Gema, Singh, Madhurendra, Gaetani, Massimiliano, Chen, Xinsong, Shi, Yao, Saei, Amir Ata, Visnes, Torkild, Lindström, Mikael S, Rihani, Ali, Moyano-Galceran, Lidia, Carlson, Joseph W, Hjerpe, Elisabet, Joneborg, Ulrika, Lehti, Kaisa, Hartman, Johan, Helleday, Thomas, Zubarev, Roman, Selivanova, Galina
Published in Cancer research (Chicago, Ill.) (01.04.2020)
Published in Cancer research (Chicago, Ill.) (01.04.2020)
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histone methyltransferase SET8 is required for S-phase progression
Jørgensen, Stine, Elvers, Ingegerd, Trelle, Morten Beck, Menzel, Tobias, Eskildsen, Morten, Jensen, Ole Nørregaard, Helleday, Thomas, Helin, Kristian, Sørensen, Claus Storgaard
Published in The Journal of cell biology (31.12.2007)
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Restriction of AID activity and somatic hypermutation by PARP-1
Tepper, Sandra, Mortusewicz, Oliver, Członka, Ewelina, Bello, Amanda, Schmidt, Angelika, Jeschke, Julia, Fischbach, Arthur, Pfeil, Ines, Petersen-Mahrt, Svend K, Mangerich, Aswin, Helleday, Thomas, Leonhardt, Heinrich, Jungnickel, Berit
Published in Nucleic acids research (22.08.2019)
Published in Nucleic acids research (22.08.2019)
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Abstract 1569: OXC-101 kills cancer by disturbing microtubule polymerization and inhibiting MTH1
Berglund, Ulrika Warpman, Gad, Helge, Sanjiv, Kumar, Jemth, Ann-Sofie, Mortusewics, Oliver, Brautigam, Lars, Rantala, Juha, Helleday, Thomas
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Poly(ADP‐ribose) polymerase (PARP‐1) has a controlling role in homologous recombination
Schultz, Niklas, Lopez, Elena, Saleh‐Gohari, Nasrollah, Helleday, Thomas
Published in Nucleic acids research (01.09.2003)
Published in Nucleic acids research (01.09.2003)
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Downregulation of SMG-1 in HPV-Positive Head and Neck Squamous Cell Carcinoma Due to Promoter Hypermethylation Correlates with Improved Survival
GUBANOVA, Evgenia, BROWN, Brandee, IVANOV, Sergei V, HELLEDAY, Thomas, MILLS, Gordon B, YARBROUGH, Wendell G, ISSAEVA, Natalia
Published in Clinical cancer research (01.03.2012)
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NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir
Zhang, Si Min, Rehling, Daniel, Jemth, Ann-Sofie, Throup, Adam, Landázuri, Natalia, Almlöf, Ingrid, Göttmann, Mona, Valerie, Nicholas C.K., Borhade, Sanjay R., Wakchaure, Prasad, Page, Brent D.G., Desroses, Matthieu, Homan, Evert J., Scobie, Martin, Rudd, Sean G., Berglund, Ulrika Warpman, Söderberg-Nauclér, Cecilia, Stenmark, Pål, Helleday, Thomas
Published in Cell chemical biology (16.12.2021)
Published in Cell chemical biology (16.12.2021)
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Front Cover: Optimization of N‐Piperidinyl‐Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8‐Oxo‐Guanine DNA Glycosylase 1 (ChemMedChem 1/2023)
Wallner, Olov, Cázares‐Körner, Armando, Scaletti, Emma Rose, Masuyer, Geoffrey, Bekkhus, Tove, Visnes, Torkild, Mamonov, Kirill, Ortis, Florian, Lundbäck, Thomas, Volkova, Maria, Koolmeister, Tobias, Wiita, Elisée, Loseva, Olga, Pandey, Monica, Homan, Evert, Benítez‐Buelga, Carlos, Davies, Jonathan, Scobie, Martin, Warpman Berglund, Ulrika, Kalderén, Christina, Stenmark, Pål, Helleday, Thomas, Michel, Maurice
Published in ChemMedChem (03.01.2023)
Published in ChemMedChem (03.01.2023)
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