Search Results - "HEKKING, Koen F. W" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Fast Iterative Synthetic Approach toward Identification of Novel Highly Selective p38 MAP Kinase Inhibitors

Fast Iterative Synthetic Approach toward Identification of Novel Highly Selective p38 MAP Kinase Inhibitors

by Röhm, Sandra, Berger, Benedict-Tilman, Schröder, Martin, Chaikuad, Apirat, Winkel, Rob, Hekking, Koen F. W, Benningshof, Jorg J. C, Müller, Gerhard, Tesch, Roberta, Kudolo, Mark, Forster, Michael, Laufer, Stefan, Knapp, Stefan
Published in Journal of medicinal chemistry (12.12.2019)

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Discovery of 2,4‑1H‑Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors

Discovery of 2,4‑1H‑Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors

by Veerman, Johan J. N, Bruseker, Yorik B, Damen, Eddy, Heijne, Erik H, van Bruggen, Wendy, Hekking, Koen F. W, Winkel, Rob, Hupp, Christopher D, Keefe, Anthony D, Liu, Julie, Thomson, Heather A, Zhang, Ying, Cuozzo, John W, McRiner, Andrew J, Mulvihill, Mark J, van Rijnsbergen, Peter, Zech, Birgit, Renzetti, Louis M, Babiss, Lee, Müller, Gerhard
Published in ACS medicinal chemistry letters (08.04.2021)

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An In-Depth Study on Ring-Closing Metathesis of Carbohydrate-Derived α-Alkoxyacrylates: Efficient Syntheses of DAH, KDO, and 2-Deoxy-β-KDO

An In-Depth Study on Ring-Closing Metathesis of Carbohydrate-Derived α-Alkoxyacrylates: Efficient Syntheses of DAH, KDO, and 2-Deoxy-β-KDO

by Hekking, Koen F. W, Moelands, Marcel A. H, van Delft, Floris L, Rutjes, Floris P. J. T
Published in Journal of organic chemistry (18.08.2006)

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A Ring-Closing Metathesis Approach to Cyclic α,β-Dehydroamino Acids

A Ring-Closing Metathesis Approach to Cyclic α,β-Dehydroamino Acids

by Hekking, Koen F. W., Waalboer, Dennis C. J., Moelands, Marcel A. H., van Delft, Floris L., Rutjes, Floris P. J. T.
Published in Advanced synthesis & catalysis (04.01.2008)

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Journal Article

Synthesis of Versatile Building Blocks through Asymmetric Hydrogenation of Functionalized Itaconic Acid Mono-Esters

Synthesis of Versatile Building Blocks through Asymmetric Hydrogenation of Functionalized Itaconic Acid Mono-Esters

by Hekking, Koen F. W., Lefort, Laurent, de Vries, André H. M., van Delft, Floris L., Schoemaker, Hans E., de Vries, Johannes G., Rutjes, Floris P. J. T.
Published in Advanced synthesis & catalysis (04.01.2008)

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헤테로사이클릭 유도체, 약학 조성물 및 암의 치료 또는 개선에서 그들의 용도

헤테로사이클릭 유도체, 약학 조성물 및 암의 치료 또는 개선에서 그들의 용도

by GRUBER DOROTHEA, FOLMER RUTGER, VEERMAN JOHAN J. N, HEKKING KOEN F. W, EERLAND MARTIJN, FLUCKIGER MANGUAL STEFANIE, FABRITIUS CHARLES HENRY
Year of Publication 13.06.2022

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Patent

Discovery of 2,4-1 H -Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors

Discovery of 2,4-1 H -Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors

by Veerman, Johan J N, Bruseker, Yorik B, Damen, Eddy, Heijne, Erik H, van Bruggen, Wendy, Hekking, Koen F W, Winkel, Rob, Hupp, Christopher D, Keefe, Anthony D, Liu, Julie, Thomson, Heather A, Zhang, Ying, Cuozzo, John W, McRiner, Andrew J, Mulvihill, Mark J, van Rijnsbergen, Peter, Zech, Birgit, Renzetti, Louis M, Babiss, Lee, Müller, Gerhard
Published in ACS medicinal chemistry letters (08.04.2021)

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Journal Article

Bivalent Ligands for Protein Degradation in Drug Discovery

Bivalent Ligands for Protein Degradation in Drug Discovery

by Scheepstra, Marcel, Hekking, Koen F.W., van Hijfte, Luc, Folmer, Rutger H.A.
Published in Computational and structural biotechnology journal (01.01.2019)

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Journal Article

Effects of Extended Aryl-Substituted Bisoxazoline Ligands in Asymmetric Synthesis - Efficient Synthesis and Application of 4,4′-Bis(1-Naphthyl)-, 4,4′-Bis(2-Naphthyl)- and 4,4′-Bis(9-Anthryl)-2,2′-isopropylidenebis(1,3-oxazolines)

Effects of Extended Aryl-Substituted Bisoxazoline Ligands in Asymmetric Synthesis - Efficient Synthesis and Application of 4,4′-Bis(1-Naphthyl)-, 4,4′-Bis(2-Naphthyl)- and 4,4′-Bis(9-Anthryl)-2,2′-isopropylidenebis(1,3-oxazolines)

by van Lingen, Hester L., van Delft, Floris L., Storcken, Roy P. M., Hekking, Koen F. W., Klaassen, Anouk, Smits, Jan J. M., Ruskowska, Patrycja, Frelek, Jadwiga, Rutjes, Floris P. J. T.
Published in European Journal of Organic Chemistry (01.12.2005)

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Book Review Journal Article

Cobalt Chloride Complexes of N 3 and N 4 Donor Ligands

Cobalt Chloride Complexes of N 3 and N 4 Donor Ligands

by Kooistra, T. Martijn, Hekking, Koen F. W., Knijnenburg, Quinten, de Bruin, Bas, Budzelaar, Peter H. M., de Gelder, René, Smits, Jan M. M., Gal, Anton W.
Published in European journal of inorganic chemistry (01.02.2003)

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Journal Article

Cobalt Chloride Complexes of N3 and N4 Donor Ligands

Cobalt Chloride Complexes of N3 and N4 Donor Ligands

by Kooistra, T. Martijn, Hekking, Koen F. W., Knijnenburg, Quinten, de Bruin, Bas, Budzelaar, Peter H. M., de Gelder, René, Smits, Jan M. M., Gal, Anton W.
Published in European journal of inorganic chemistry (01.02.2003)

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Journal Article

An Efficient Synthesis of 1-Naphthylbis(oxazoline) and Exploration of the Scope in Asymmetric Catalysis

An Efficient Synthesis of 1-Naphthylbis(oxazoline) and Exploration of the Scope in Asymmetric Catalysis

by van Lingen, Hester L., van de Mortel, Jeroen K. W., Hekking, Koen F. W., van Delft, Floris L., Sonke, Theo, Rutjes, Floris P. J. T.
Published in European journal of organic chemistry (01.01.2003)

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Journal Article

Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer

Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer

by EERLAND, Martijn, FOLMER, Rutger, FABRITIUS, Charles-Henry, GRUBER, Dorothea, FLÜCKIGER-MANGUAL, Stefanie, HEKKING, Koen F. W, VEERMAN, Johan J. N
Year of Publication 15.02.2024

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Patent

HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER

HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER

by EERLAND, Martijn, FOLMER, Rutger, FABRITIUS, Charles-Henry, GRUBER, Dorothea, FLÜCKIGER-MANGUAL, Stefanie, HEKKING, Koen F. W, VEERMAN, Johan J. N
Year of Publication 17.08.2022

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Patent

Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer

Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer

by EERLAND, Martijn, FOLMER, Rutger, FABRITIUS, Charles-Henry, GRUBER, Dorothea, FLÜCKIGER-MANGUAL, Stefanie, HEKKING, Koen F. W, VEERMAN, Johan J. N
Year of Publication 24.02.2022

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Patent

HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER

HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER

by EERLAND, Martijn, FOLMER, Rutger, FABRITIUS, Charles-Henry, GRUBER, Dorothea, FLÜCKIGER-MANGUAL, Stefanie, HEKKING, Koen F. W, VEERMAN, Johan J. N
Year of Publication 08.04.2021

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Patent

HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER

HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER

by VEERMAN, JOHAN J. N, FLUCKIGER-MANGUAL, STEFANIE, GRUBER, DOROTHEA, FOLMER, RUTGER, FABRITIUS, CHARLES-HENRY, EERLAND, MARTIJN, HEKKING, KOEN F. W
Year of Publication 08.04.2021

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Patent

DERIVADOS HETEROCÍCLICOS, COMPOSIÇÕES FARMACÊUTICAS E SEU USO NO TRATAMENTO OU MELHORA DO CÂNCER

DERIVADOS HETEROCÍCLICOS, COMPOSIÇÕES FARMACÊUTICAS E SEU USO NO TRATAMENTO OU MELHORA DO CÂNCER

by STEFANIE FLÜCKIGER-MANGUAL, CHARLES-HENRY FABRITIUS, DOROTHEA GRUBER, RUTGER FOLMER, KOEN F. W. HEKKING, JOHAN J. N. VEERMAN, MARTIJN EERLAND
Year of Publication 26.07.2022

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Patent

HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER

HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER

by FABRITIUS Charles-henry, HEKKING Koen F. W, FLÜCKIGER-MANGUAL Stefanie, VEERMAN Johan J. N, GRUBER Dorothea, FOLMER Rutger, EERLAND Martijn
Year of Publication 30.05.2022

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Patent

ChemInform Abstract: Synthesis of Versatile Building Blocks Through Asymmetric Hydrogenation of Functionalized Itaconic Acid Mono-Esters

ChemInform Abstract: Synthesis of Versatile Building Blocks Through Asymmetric Hydrogenation of Functionalized Itaconic Acid Mono-Esters

by Hekking, Koen F. W., Lefort, Laurent, de Vries, Andre H. M., van Delft, Floris L., Schoemaker, Hans E., de Vries, Johannes G., Rutjes, Floris P. J. T.
Published in ChemInform (20.05.2008)

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Journal Article