Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876
Siebeneicher, Holger, Cleve, Arwed, Rehwinkel, Hartmut, Neuhaus, Roland, Heisler, Iring, Müller, Thomas, Bauser, Marcus, Buchmann, Bernd
Published in ChemMedChem (19.10.2016)
Published in ChemMedChem (19.10.2016)
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Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides
Kapoor, Khyati, Finer-Moore, Janet S., Pedersen, Bjørn P., Caboni, Laura, Waight, Andrew, Hillig, Roman C., Bringmann, Peter, Heisler, Iring, Müller, Thomas, Siebeneicher, Holger, Stroud, Robert M.
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.2016)
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BAY 87‐2243, a highly potent and selective inhibitor of hypoxia‐induced gene activation has antitumor activities by inhibition of mitochondrial complex I
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Comparison of electrophysiological and motility assays to study anthelmintic effects in Caenorhabditis elegans
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Published in International journal for parasitology -- drugs and drug resistance (01.08.2021)
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Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A
Friberg, Anders, Rehwinkel, Hartmut, Nguyen, Duy, Pütter, Vera, Quanz, Maria, Weiske, Jörg, Eberspächer, Uwe, Heisler, Iring, Langer, Gernot
Published in ACS omega (09.06.2020)
Published in ACS omega (09.06.2020)
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Combined application of saponin and chimeric toxins drastically enhances the targeted cytotoxicity on tumor cells
Heisler, Iring, Sutherland, Mark, Bachran, Christopher, Hebestreit, Philipp, Schnitger, Anna, Melzig, Matthias F., Fuchs, Hendrik
Published in Journal of controlled release (18.08.2005)
Published in Journal of controlled release (18.08.2005)
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The saponin-mediated enhanced uptake of targeted saporin-based drugs is strongly dependent on the saponin structure
Bachran, Christopher, Sutherland, Mark, Heisler, Iring, Hebestreit, Philipp, Melzig, Matthias F, Fuchs, Hendrik
Published in Experimental biology and medicine (Maywood, N.J.) (01.04.2006)
Published in Experimental biology and medicine (Maywood, N.J.) (01.04.2006)
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Chimeric toxins inhibit growth of primary oral squamous cell carcinoma cells
Bachran, Christopher, Heisler, Iring, Bachran, Diana, Dassler, Katrin, Melzig, Matthias F., Ervens, Jürgen, Fuchs, Hendrik
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Published in Cancer biology & therapy (01.02.2008)
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Anetumab ravtansine: a novel mesothelin-targeting antibody-drug conjugate cures tumors with heterogeneous target expression favored by bystander effect
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Published in Molecular cancer therapeutics (01.06.2014)
Published in Molecular cancer therapeutics (01.06.2014)
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신규 퀴놀린 유도체
KULKE DANIEL, SELBACH CLAUDIA, HEISLER IRING, HUBSCH WALTER, ZHUANG WEI, GRIEBENOW NILS, TAHTAOUI CHOUAIB, BOERNGEN KIRSTEN
Year of Publication 30.04.2024
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Year of Publication 30.04.2024
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Identification of novel GLUT inhibitors
Siebeneicher, Holger, Bauser, Marcus, Buchmann, Bernd, Heisler, Iring, Müller, Thomas, Neuhaus, Roland, Rehwinkel, Hartmut, Telser, Joachim, Zorn, Ludwig
Published in Bioorganic & medicinal chemistry letters (01.04.2016)
Published in Bioorganic & medicinal chemistry letters (01.04.2016)
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Abstract 4333: Identification and optimization of the first highly selective GLUT-1 inhibitors
Bauser, Marcus, Buchmann, Bernd, Siebeneicher, Holger, Cleve, Arwed, Rehwinkel, Hartmut, Neuhaus, Roland, Heisler, Iring, Mueller, Thomas, Kopitz, Charlotte Christine
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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농약제로서 신규 피라지닐-트리아졸 화합물
JESCHKE PETER, EBBINGHAUS KINTSCHER ULRICH, LOESEL PETER, TELSER JOACHIM, BAER ROBIN MAXIMILIAN, LINKA MARC, DAMIJONAITIS ARUNAS, FUESSLEIN MARTIN, WINTER PHILIPP, SCHWARZ HANS GEORG, TURBERG ANDREAS, HEISLER IRING, CANCHO GRANDE YOLANDA
Year of Publication 19.04.2024
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Year of Publication 19.04.2024
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알킬아미드 치환된, 환형 이미다졸 및 살충제로서의 이의 용도
JESCHKE PETER, EBBINGHAUS KINTSCHER ULRICH, LOESEL PETER, TELSER JOACHIM, BAER ROBIN MAXIMILIAN, MUELLER STEFFEN, FUESSLEIN MARTIN, WINTER PHILIPP, SCHWARZ HANS GEORG, TURBERG ANDREAS, HEISLER IRING, DAMIJONAITIS ARUNAS JONAS, CANCHO GRANDE YOLANDA
Year of Publication 11.01.2024
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Year of Publication 11.01.2024
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Abstract 1164: Metabolic responses in cancer cells with differential susceptibility to GLUT1 inhibition
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Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Cover Picture: Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876 (ChemMedChem 20/2016)
Siebeneicher, Holger, Cleve, Arwed, Rehwinkel, Hartmut, Neuhaus, Roland, Heisler, Iring, Müller, Thomas, Bauser, Marcus, Buchmann, Bernd
Published in ChemMedChem (19.10.2016)
Published in ChemMedChem (19.10.2016)
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Abstract 4746: Pharmacological characterization of BAY-876, a novel highly selective inhibitor of glucose transporter (GLUT)-1 in vitro and in vivo
Kopitz, Charlotte, Toschi, Luisella, Algire, Carolyn, Héroult, Mélanie, Frisk, Anna-Lena, Meyer, Kirstin, Schmitz, Arndt, Lagkadinou, Eleni, Petrul, Heike, Heisler, Iring, Neuhaus, Roland, Buchmann, Bernd, Himmel, Herbert, Bauser, Marcus, Haegebarth, Andrea, Ziegelbauer, Karl
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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살충제로서의 신규 헤테로아릴-트리아졸 화합물
ARLT ALEXANDER, JESCHKE PETER, EBBINGHAUS KINTSCHER ULRICH, LOESEL PETER, SCHWARZ HANS GEORG, HEISLER IRING, TURBERG ANDREAS, TELSER JOACHIM, LINKA MARC, DAMIJONAITIS ARUNAS JONAS, FUESSLEIN MARTIN, CANCHO GRANDE YOLANDA
Year of Publication 20.07.2022
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Year of Publication 20.07.2022
Patent