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Published in Journal of clinical oncology (15.09.2004)
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Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients
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Primary and Secondary Kinase Genotypes Correlate With the Biological and Clinical Activity of Sunitinib in Imatinib-Resistant Gastrointestinal Stromal Tumor
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Published in Journal of clinical oncology (20.11.2008)
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Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase Domain
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Long-Term Results From a Randomized Phase II Trial of Standard- Versus Higher-Dose Imatinib Mesylate for Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing KIT
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Published in Journal of clinical oncology (01.02.2008)
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KIT Gene Mutations and Copy Number in Melanoma Subtypes
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A smooth muscle‐derived, Braf‐driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell‐of‐origin
Kondo, Jumpei, Huh, Won Jae, Franklin, Jeffrey L, Heinrich, Michael C, Rubin, Brian P, Coffey, Robert J
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Patient-reported outcomes in individuals with advanced gastrointestinal stromal tumor treated with ripretinib in the fourth-line setting: analysis from the phase 3 INVICTUS trial
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Published in Future oncology (London, England) (01.01.2020)
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Phase III Randomized, Intergroup Trial Assessing Imatinib Mesylate At Two Dose Levels in Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing the Kit Receptor Tyrosine Kinase: S0033
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Crosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug Resistance
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Phase II Study of Nilotinib in Melanoma Harboring KIT Alterations Following Progression to Prior KIT Inhibition
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George, Suzanne, Wang, Qian, Heinrich, Michael C, Corless, Christopher L, Zhu, Meijun, Butrynski, James E, Morgan, Jeffrey A, Wagner, Andrew J, Choy, Edwin, Tap, William D, Yap, Jeffrey T, Van den Abbeele, Annick D, Manola, Judith B, Solomon, Sarah M, Fletcher, Jonathan A, von Mehren, Margaret, Demetri, George D
Published in Journal of clinical oncology (01.07.2012)
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Linsitinib (OSI-906) for the Treatment of Adult and Pediatric Wild-Type Gastrointestinal Stromal Tumors, a SARC Phase II Study
von Mehren, Margaret, George, Suzanne, Heinrich, Michael C, Schuetze, Scott M, Yap, Jeffrey T, Yu, Jain Q, Abbott, Amanda, Litwin, Samuel, Crowley, John, Belinsky, Martin, Janeway, Katherine A, Hornick, Jason L, Flieder, Douglas B, Chugh, Rashmi, Rink, Lori, Van den Abbeele, Annick D
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Published in Clinical cancer research (15.04.2020)
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