Phage Selection of Cyclic Peptides for Application in Research and Drug Development
Deyle, Kaycie, Kong, Xu-Dong, Heinis, Christian
Published in Accounts of chemical research (15.08.2017)
Published in Accounts of chemical research (15.08.2017)
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Journal Article
Phage-encoded combinatorial chemical libraries based on bicyclic peptides
Heinis, Christian, Winter, Greg, Rutherford, Trevor, Freund, Stephan
Published in Nature Chemical Biology (01.07.2009)
Published in Nature Chemical Biology (01.07.2009)
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Journal Article
Peptide Ligands Stabilized by Small Molecules
Chen, Shiyu, Bertoldo, Davide, Angelini, Alessandro, Pojer, Florence, Heinis, Christian
Published in Angewandte Chemie (International ed.) (03.02.2014)
Published in Angewandte Chemie (International ed.) (03.02.2014)
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Journal Article
Combination of polycarboxybetaine coating and factor XII inhibitor reduces clot formation while preserving normal tissue coagulation during extracorporeal life support
Naito, Noritsugu, Ukita, Rei, Wilbs, Jonas, Wu, Kan, Lin, Xiaojie, Carleton, Neil M., Roberts, Kalliope, Jiang, Shaoyi, Heinis, Christian, Cook, Keith E.
Published in Biomaterials (01.05.2021)
Published in Biomaterials (01.05.2021)
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Journal Article
Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs
Wilbs, Jonas, Kong, Xu-Dong, Middendorp, Simon J., Prince, Raja, Cooke, Alida, Demarest, Caitlin T., Abdelhafez, Mai M., Roberts, Kalliope, Umei, Nao, Gonschorek, Patrick, Lamers, Christina, Deyle, Kaycie, Rieben, Robert, Cook, Keith E., Angelillo-Scherrer, Anne, Heinis, Christian
Published in Nature communications (04.08.2020)
Published in Nature communications (04.08.2020)
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Journal Article
Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale
Habeshian, Sevan, Merz, Manuel Leonardo, Sangouard, Gontran, Mothukuri, Ganesh Kumar, Schüttel, Mischa, Bognár, Zsolt, Díaz-Perlas, Cristina, Vesin, Jonathan, Bortoli Chapalay, Julien, Turcatti, Gerardo, Cendron, Laura, Angelini, Alessandro, Heinis, Christian
Published in Nature communications (02.07.2022)
Published in Nature communications (02.07.2022)
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Journal Article
High-affinity peptides developed against calprotectin and their application as synthetic ligands in diagnostic assays
Díaz-Perlas, Cristina, Ricken, Benjamin, Farrera-Soler, Lluc, Guschin, Dmitrii, Pojer, Florence, Lau, Kelvin, Gerhold, Christian-Benedikt, Heinis, Christian
Published in Nature communications (17.05.2023)
Published in Nature communications (17.05.2023)
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Journal Article
Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides
Chen, Shiyu, Gopalakrishnan, Ranganath, Schaer, Tifany, Marger, Fabrice, Hovius, Ruud, Bertrand, Daniel, Pojer, Florence, Heinis, Christian
Published in Nature chemistry (01.11.2014)
Published in Nature chemistry (01.11.2014)
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Journal Article
Phage Selection of Photoswitchable Peptide Ligands
Bellotto, Silvia, Chen, Shiyu, Rentero Rebollo, Inmaculada, Wegner, Hermann A, Heinis, Christian
Published in Journal of the American Chemical Society (23.04.2014)
Published in Journal of the American Chemical Society (23.04.2014)
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Journal Article
Phage selection of bicyclic peptides based on two disulfide bridges
Chen, Shiyu, Heinis, Christian
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2015)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2015)
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Journal Article
Boosting the Sensitivity of Ligand–Protein Screening by NMR of Long-Lived States
Salvi, Nicola, Buratto, Roberto, Bornet, Aurélien, Ulzega, Simone, Rentero Rebollo, Inmaculada, Angelini, Alessandro, Heinis, Christian, Bodenhausen, Geoffrey
Published in Journal of the American Chemical Society (11.07.2012)
Published in Journal of the American Chemical Society (11.07.2012)
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Journal Article
Development of a Selective Peptide Macrocycle Inhibitor of Coagulation Factor XII toward the Generation of a Safe Antithrombotic Therapy
Baeriswyl, Vanessa, Calzavarini, Sara, Gerschheimer, Christiane, Diderich, Philippe, Angelillo-Scherrer, Anne, Heinis, Christian
Published in Journal of medicinal chemistry (09.05.2013)
Published in Journal of medicinal chemistry (09.05.2013)
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Journal Article
Structurally Diverse Cyclisation Linkers Impose Different Backbone Conformations in Bicyclic Peptides
Chen, Shiyu, Morales-Sanfrutos, Julia, Angelini, Alessandro, Cutting, Brian, Heinis, Christian
Published in Chembiochem : a European journal of chemical biology (07.05.2012)
Published in Chembiochem : a European journal of chemical biology (07.05.2012)
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Journal Article
Post-translational modification of genetically encoded polypeptide libraries
Angelini, Alessandro, Heinis, Christian
Published in Current opinion in chemical biology (01.06.2011)
Published in Current opinion in chemical biology (01.06.2011)
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