ISG15 is a critical microenvironmental factor for pancreatic cancer stem cells
Sainz, Jr, Bruno, Martín, Beatriz, Tatari, Marianthi, Heeschen, Christopher, Guerra, Susana
Published in Cancer research (Chicago, Ill.) (15.12.2014)
Published in Cancer research (Chicago, Ill.) (15.12.2014)
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Bioengineered 3D models of human pancreatic cancer recapitulate in vivo tumour biology
Osuna de la Peña, David, Trabulo, Sara Maria David, Collin, Estelle, Liu, Ying, Sharma, Shreya, Tatari, Marianthi, Behrens, Diana, Erkan, Mert, Lawlor, Rita T, Scarpa, Aldo, Heeschen, Christopher, Mata, Alvaro, Loessner, Daniela
Published in Nature communications (24.09.2021)
Published in Nature communications (24.09.2021)
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Concise Review: Stem Cells in Pancreatic Cancer: From Concept to Translation
Raj, Deepak, Aicher, Alexandra, Heeschen, Christopher
Published in Stem cells (Dayton, Ohio) (01.10.2015)
Published in Stem cells (Dayton, Ohio) (01.10.2015)
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Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
Hermann, Patrick C, Huber, Stephan L, Herrler, Tanja, Aicher, Alexandra, Ellwart, Joachim W, Guba, Markus, Bruns, Christiane J, Heeschen, Christopher
Published in Cell stem cell (13.09.2007)
Published in Cell stem cell (13.09.2007)
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Circulating cancer stem cells: the importance to select
Yang, Ming-Hsin, Imrali, Ahmet, Heeschen, Christopher
Published in Chinese journal of cancer research (01.10.2015)
Published in Chinese journal of cancer research (01.10.2015)
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TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression
Ottaviani, Silvia, Stebbing, Justin, Frampton, Adam E, Zagorac, Sladjana, Krell, Jonathan, de Giorgio, Alexander, Trabulo, Sara M, Nguyen, Van T M, Magnani, Luca, Feng, Hugang, Giovannetti, Elisa, Funel, Niccola, Gress, Thomas M, Jiao, Long R, Lombardo, Ylenia, Lemoine, Nicholas R, Heeschen, Christopher, Castellano, Leandro
Published in Nature communications (10.05.2018)
Published in Nature communications (10.05.2018)
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Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells
Valle, Sandra, Alcalá, Sonia, Martin-Hijano, Laura, Cabezas-Sáinz, Pablo, Navarro, Diego, Muñoz, Edurne Ramos, Yuste, Lourdes, Tiwary, Kanishka, Walter, Karolin, Ruiz-Cañas, Laura, Alonso-Nocelo, Marta, Rubiolo, Juan A, González-Arnay, Emilio, Heeschen, Christopher, Garcia-Bermejo, Laura, Hermann, Patrick C, Sánchez, Laura, Sancho, Patricia, Fernández-Moreno, Miguel Ángel, Sainz, Jr, Bruno
Published in Nature communications (16.10.2020)
Published in Nature communications (16.10.2020)
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The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner
Agerbæk, Mette Ø, Bang-Christensen, Sara R, Yang, Ming-Hsin, Clausen, Thomas M, Pereira, Marina A, Sharma, Shreya, Ditlev, Sisse B, Nielsen, Morten A, Choudhary, Swati, Gustavsson, Tobias, Sorensen, Poul H, Meyer, Tim, Propper, David, Shamash, Jonathan, Theander, Thor G, Aicher, Alexandra, Daugaard, Mads, Heeschen, Christopher, Salanti, Ali
Published in Nature communications (16.08.2018)
Published in Nature communications (16.08.2018)
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Chloroquine targets pancreatic cancer stem cells via inhibition of CXCR4 and hedgehog signaling
Balic, Anamaria, Sørensen, Morten Dræby, Trabulo, Sara Maria, Sainz, Jr, Bruno, Cioffi, Michele, Vieira, Catarina R, Miranda-Lorenzo, Irene, Hidalgo, Manuel, Kleeff, Joerg, Erkan, Mert, Heeschen, Christopher
Published in Molecular cancer therapeutics (01.07.2014)
Published in Molecular cancer therapeutics (01.07.2014)
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Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells
Lonardo, Enza, Cioffi, Michele, Sancho, Patricia, Sanchez-Ripoll, Yolanda, Trabulo, Sara Maria, Dorado, Jorge, Balic, Anamaria, Hidalgo, Manuel, Heeschen, Christopher
Published in PloS one (18.10.2013)
Published in PloS one (18.10.2013)
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Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer
Mueller, Maria-Theresa, Hermann, Patrick C, Witthauer, Juliane, Rubio-Viqueira, Belen, Leicht, Simon F, Huber, Stephan, Ellwart, Joachim W, Mustafa, Mona, Bartenstein, Peter, D'Haese, Jan G, Schoenberg, Michael H, Berger, Frank, Jauch, Karl-Walter, Hidalgo, Manuel, Heeschen, Christopher
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2009)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2009)
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Fatty acid oxidation is critical for the tumorigenic potential and chemoresistance of pancreatic cancer stem cells
Mascaraque, Marta, Courtois, Sarah, Royo-García, Alba, Barneda, David, Stoian, Andrei M, Villaoslada, Isabel, Espiau-Romera, Pilar, Bokil, Ansooya, Cano-Galiano, Andrés, Jagust, Petra, Heeschen, Christopher, Sancho, Patricia
Published in Journal of translational medicine (28.08.2024)
Published in Journal of translational medicine (28.08.2024)
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Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
Dimmeler, Stefanie, Aicher, Alexandra, Heeschen, Christopher, Mildner-Rihm, Christiane, Urbich, Carmen, Ihling, Christian, Technau-Ihling, Katja, Zeiher, Andreas M
Published in Nature medicine (01.11.2003)
Published in Nature medicine (01.11.2003)
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Nicotine Promotes Initiation and Progression of KRAS-Induced Pancreatic Cancer via Gata6- Dependent Dedifferentiation of Acinar Cells in Mice
Hermann, Patrick C, Sancho, Patricia, Cañamero, Marta, Martinelli, Paola, Madriles, Francesc, Michl, Patrick, Gress, Thomas, de Pascual, Ricardo, Gandia, Luis, Guerra, Carmen, Barbacid, Mariano, Wagner, Martin, Vieira, Catarina R, Aicher, Alexandra, Real, Francisco X, Sainz, Bruno, Heeschen, Christopher
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2014)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2014)
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LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer
Cave, Donatella Delle, Buonaiuto, Silvia, Sainz, Jr, Bruno, Fantuz, Marco, Mangini, Maria, Carrer, Alessandro, Di Domenico, Annalisa, Iavazzo, Tea Teresa, Andolfi, Gennaro, Cortina, Carme, Sevillano, Marta, Heeschen, Christopher, Colonna, Vincenza, Corona, Marco, Cucciardi, Antonio, Di Guida, Martina, Batlle, Eduard, De Luca, Annachiara, Lonardo, Enza
Published in Journal of experimental & clinical cancer research (26.10.2022)
Published in Journal of experimental & clinical cancer research (26.10.2022)
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Pharmacological targeting of the receptor ALK inhibits tumorigenicity and overcomes chemoresistance in pancreatic ductal adenocarcinoma
Parejo-Alonso, Beatriz, Royo-García, Alba, Espiau-Romera, Pilar, Courtois, Sarah, Curiel-García, Álvaro, Zagorac, Sladjana, Villaoslada, Isabel, Olive, Kenneth P., Heeschen, Christopher, Sancho, Patricia
Published in Biomedicine & pharmacotherapy (01.02.2023)
Published in Biomedicine & pharmacotherapy (01.02.2023)
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Inhibition of Ataxia Telangiectasia‐ and Rad3 ‐Related Function Abrogates the In Vitro and In Vivo Tumorigenicity of Human Colon Cancer Cells Through Depletion of the CD133+ Tumor‐Initiating Cell Fraction
Gallmeier, Eike, Hermann, Patrick C., Mueller, Maria‐Theresa, Machado, Juan G., Ziesch, Andreas, De Toni, Enrico N., Palagyi, Andreas, Eisen, Christian, Ellwart, Joachim W., Rivera, Jose, Rubio‐Viqueira, Belen, Hidalgo, Manuel, Bunz, Fred, Göke, Burkhard, Heeschen, Christopher
Published in Stem cells (Dayton, Ohio) (01.03.2011)
Published in Stem cells (Dayton, Ohio) (01.03.2011)
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The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1
Cioffi, Michele, Trabulo, Sara M, Vallespinos, Mireia, Raj, Deepak, Kheir, Tony Bou, Lin, Meng-Lay, Begum, Julfa, Baker, Ann-Marie, Amgheib, Ala, Saif, Jaimy, Perez, Manuel, Soriano, Joaquim, Desco, Manuel, Gomez-Gaviro, Maria Victoria, Cusso, Lorena, Megias, Diego, Aicher, Alexandra, Heeschen, Christopher
Published in Oncotarget (28.03.2017)
Published in Oncotarget (28.03.2017)
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Pancreatic cancer stem cells: new insights and perspectives
Dorado, Jorge, Lonardo, Enza, Miranda-Lorenzo, Irene, Heeschen, Christopher
Published in Journal of gastroenterology (01.08.2011)
Published in Journal of gastroenterology (01.08.2011)
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