Astodrimer sodium nasal spray forms a barrier to SARS-CoV-2 in vitro and preserves normal mucociliary function in human nasal epithelium
Paull, Jeremy R. A., Luscombe, Carolyn A., Seta, Aynaz, Heery, Graham P., Bobardt, Michael D., Gallay, Philippe A., Constant, Samuel, Castellarnau, Alex
Published in Scientific reports (11.09.2024)
Published in Scientific reports (11.09.2024)
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Journal Article
Astodrimer sodium antiviral nasal spray for reducing respiratory infections is safe and well tolerated in a randomized controlled trial
Castellarnau, Alex, Heery, Graham P., Seta, Aynaz, Luscombe, Carolyn A., Kinghorn, George R., Button, Peter, McCloud, Philip, Paull, Jeremy R. A.
Published in Scientific reports (17.06.2022)
Published in Scientific reports (17.06.2022)
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Journal Article
Topical Astodrimer Sodium, a Non-Toxic Polyanionic Dendrimer, Demonstrates Antiviral Activity in an Experimental Ocular Adenovirus Infection Model
Romanowski, Eric G, Yates, Kathleen A, Paull, Jeremy R A, Heery, Graham P, Shanks, Robert M Q
Published in Molecules (Basel, Switzerland) (05.06.2021)
Published in Molecules (Basel, Switzerland) (05.06.2021)
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Journal Article
Protective Effects of Astodrimer Sodium 1% Nasal Spray Formulation against SARS-CoV-2 Nasal Challenge in K18-hACE2 Mice
Paull, Jeremy R. A., Luscombe, Carolyn A., Castellarnau, Alex, Heery, Graham P., Bobardt, Michael D., Gallay, Philippe A.
Published in Viruses (20.08.2021)
Published in Viruses (20.08.2021)
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Journal Article
Dendrimers as Drugs: Discovery and Preclinical and Clinical Development of Dendrimer-Based Microbicides for HIV and STI Prevention
McCarthy, Tom D., Karellas, Peter, Henderson, Scott A., Giannis, Michael, O'Keefe, David F., Heery, Graham, Paull, Jeremy R. A., Matthews, Barry R., Holan, George
Published in Molecular pharmaceutics (01.07.2005)
Published in Molecular pharmaceutics (01.07.2005)
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Journal Article
Dendrimers As Drugs: Discovery, Preclinical and Clinical Development of SPL7013 Gel (VivaGel™), a Dendrimer Based Microbicide for HIVand STI Prevention
McCarthy, Tom, Karellas, Peter, Henderson, Scott, Giannis, Michael, O'Keefe, David, Heery, Graham, Paull, Jeremy, Matthews, Barry, Holan, George
Published in Retrovirology (08.12.2005)
Published in Retrovirology (08.12.2005)
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Abstract 1715: Anti-cancer activity of a SN-38 nanoparticle, DEP® irinotecan, in human colon cancer xenograft models
Kelly, Brian D., McLeod, Victoria, Walker, Rachael, Schreuders, Jeannette, Jackson, Susan, Giannis, Michael, Dietinger, Christine, Xia, Shirley, Cargill, Anne, Seta, Aynaz, Hufton, Richard, Heery, Graham, Cullinane, Carleen, Owen, David J.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 1716: Anticancer activity of the taxane nanoparticles, DEP® docetaxel and DEP® cabazitaxel
Kelly, Brian D., McLeod, Victoria, Walker, Rachael, Schreuders, Jeannette, Jackson, Susan, Giannis, Michael, Dietinger, Christine, Reitano, Pauline, Pathak, Rashmi, Xia, Shirley, Cargill, Anne, Seta, Aynaz, Hufton, Richard, Heery, Graham, Cullinane, Carleen, Owen, David J.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract C167: An SN38 dendrimer nanoparticle, DEP irinotecan (SN38-SPL9111), demonstrates efficacy in mouse models of gastrointestinal cancer and augments anti-tumor effects of immune checkpoint blockade and PARP inhibition
Blyth, Benjamin J, Kelly, Brian D, Giannis, Michael, Cargill, Anne, Seta, Aynaz, Heery, Graham P, Eglezos, Anthony, Johnstone, Cameron N, Paull, Jeremy R A
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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Abstract A147: A HER2 targeted polylysine dendrimer nanoparticle radiotheranostic demonstrates excellent tumor accumulation, rapid clearance from circulation, and promising performance in PET-CT imaging
Johnstone, Cameron N, Heery, Graham P, Kelly, Brian D, Humphries, James, Akhter, Dewan T, Thurecht, Kristofer J, Yuen, Daniel, Giannis, Michael, Yong, Ken, Chadwick, Gareth, Barker, Helena, Cargill, Anne, Eglezos, Anthony, Castellarnau, Alex, Paull, Jeremy R A, Hufton, Richard
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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Journal Article
METHOD OF PROPHYLAXIS OF CORONAVIRUS AND/OR RESPIRATORY SYNCYTIAL VIRUS INFECTION
Fairley, Jacinth, Heery, Graham, Dong, Yao Da, Paull, Jeremy Robert Arthur, Huberman, Jessica
Year of Publication 19.10.2023
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Year of Publication 19.10.2023
Patent
Macromolecule for prophylaxis of Coronavirus
Graham Heery, Jeremy Robert Arthur Paull, Jacinth Fairley, Jessica Huberman, Yao Da Dong
Year of Publication 05.04.2023
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Year of Publication 05.04.2023
Patent
METHOD OF PROPHYLAXIS OF CORONAVIRUS AND/OR RESPIRATORY SYNCYTIAL VIRUS INFECTION
FAIRLEY, Jacinth, HUBERMAN, Jessica, PAULL, Jeremy Robert Arthur, DONG, Yao Da, HEERY, Graham
Year of Publication 11.05.2022
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Year of Publication 11.05.2022
Patent
Method of prophylaxis of Coronavirus and/or respiratory syncytial virus infection
Graham Heery, Jeremy Robert Arthur Paull, Jacinth Fairley, Jessica Huberman, Yao Da Dong
Year of Publication 13.04.2022
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Year of Publication 13.04.2022
Patent
METHOD OF PROPHYLAXIS OF CORONAVIRUS AND/OR RESPIRATORY SYNCYTIAL VIRUS INFECTION
FAIRLEY, Jacinth, HUBERMAN, Jessica, PAULL, Jeremy Robert Arthur, DONG, Yao Da, HEERY, Graham
Year of Publication 05.01.2022
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Year of Publication 05.01.2022
Patent