Naturally Occurring Isothiocyanates Exert Anticancer Effects by Inhibiting Deubiquitinating Enzymes
Lawson, Ann P, Long, Marcus J C, Coffey, Rory T, Qian, Yu, Weerapana, Eranthie, El Oualid, Farid, Hedstrom, Lizbeth
Published in Cancer research (Chicago, Ill.) (01.12.2015)
Published in Cancer research (Chicago, Ill.) (01.12.2015)
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Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase
Gorla, Suresh Kumar, Kavitha, Mandapati, Zhang, Minjia, Chin, James En Wai, Liu, Xiaoping, Striepen, Boris, Makowska-Grzyska, Magdalena, Kim, Youngchang, Joachimiak, Andrzej, Hedstrom, Lizbeth, Cuny, Gregory D
Published in Journal of medicinal chemistry (23.05.2013)
Published in Journal of medicinal chemistry (23.05.2013)
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Validation of IMP Dehydrogenase Inhibitors in a Mouse Model of Cryptosporidiosis
SURESH KUMAR GORLA, MCNAIR, Nina N, HEDSTROM, Lizbeth, GUANGYI YANG, SONG GAO, MING HU, JALA, Venkatakrishna R, HARIBABU, Bodduluri, STRIEPEN, Boris, CUNY, Gregory D, MEAD, Jan R
Published in Antimicrobial Agents and Chemotherapy (01.03.2014)
Published in Antimicrobial Agents and Chemotherapy (01.03.2014)
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Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds
Makowska-Grzyska, Magdalena, Kim, Youngchang, Gorla, Suresh Kumar, Wei, Yang, Mandapati, Kavitha, Zhang, Minjia, Maltseva, Natalia, Modi, Gyan, Boshoff, Helena I, Gu, Minyi, Aldrich, Courtney, Cuny, Gregory D, Hedstrom, Lizbeth, Joachimiak, Andrzej
Published in PloS one (06.10.2015)
Published in PloS one (06.10.2015)
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Triazole Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase
Maurya, Sushil K, Gollapalli, Deviprasad R, Kirubakaran, Shivapriya, Zhang, Minjia, Johnson, Corey R, Benjamin, Nicole N, Hedstrom, Lizbeth, Cuny, Gregory D
Published in Journal of medicinal chemistry (13.08.2009)
Published in Journal of medicinal chemistry (13.08.2009)
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A call to arms: Unifying the fight against resistance
Kaushansky, Alexis, Hedstrom, Lizbeth, Goldman, Aaron, Singh, Juswinder, Yang, Priscilla L, Rathod, Pradipsinh K, Cynamon, Michael, Wodarz, Dominik, Mahadevan, Daruka, Tomaras, Andrew, Navia, Manuel A, Schiffer, Celia A
Published in Science signaling (23.10.2018)
Published in Science signaling (23.10.2018)
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Structure–activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH
Kirubakaran, Sivapriya, Gorla, Suresh Kumar, Sharling, Lisa, Zhang, Minjia, Liu, Xiaoping, Ray, Soumya S., MacPherson, Iain S., Striepen, Boris, Hedstrom, Lizbeth, Cuny, Gregory D.
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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Journal Article
Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry
Lawson, Ann P, Bak, Daniel W, Shannon, D Alexander, Long, Marcus J C, Vijaykumar, Tushara, Yu, Runhan, Oualid, Farid El, Weerapana, Eranthie, Hedstrom, Lizbeth
Published in Oncotarget (01.08.2017)
Published in Oncotarget (01.08.2017)
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A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase
Sharling, Lisa, Liu, Xiaoping, Gollapalli, Deviprasad R, Maurya, Sushil K, Hedstrom, Lizbeth, Striepen, Boris
Published in PLoS neglected tropical diseases (10.08.2010)
Published in PLoS neglected tropical diseases (10.08.2010)
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Gene Transfer in the Evolution of Parasite Nucleotide Biosynthesis
Striepen, Boris, Andrea J. P. Pruijssers, Huang, Jinling, Li, Catherine, Gubbels, Marc-Jan, Umejiego, Nwakaso N., Hedstrom, Lizbeth, Kissinger, Jessica C., Palmer, Jeffrey D.
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)
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Repurposing Cryptosporidium Inosine 5′-Monophosphate Dehydrogenase Inhibitors as Potential Antibacterial Agents
Mandapati, Kavitha, Gorla, Suresh Kumar, House, Amanda L, McKenney, Elizabeth S, Zhang, Minjia, Rao, Suraj Nagendra, Gollapalli, Deviprasad R, Mann, Barbara J, Goldberg, Joanna B, Cuny, Gregory D, Glomski, Ian J, Hedstrom, Lizbeth
Published in ACS medicinal chemistry letters (14.08.2014)
Published in ACS medicinal chemistry letters (14.08.2014)
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Journal Article
IMP Dehydrogenase Type 1 Associates with Polyribosomes Translating Rhodopsin mRNA
Mortimer, Sarah E., Xu, Dong, McGrew, Dharia, Hamaguchi, Nobuko, Lim, Hoong Chuin, Bowne, Sara J., Daiger, Stephen P., Hedstrom, Lizbeth
Published in The Journal of biological chemistry (26.12.2008)
Published in The Journal of biological chemistry (26.12.2008)
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