Dual Targeting of Wild-Type and Mutant p53 by Small Molecule RITA Results in the Inhibition of N-Myc and Key Survival Oncogenes and Kills Neuroblastoma Cells In Vivo and In Vitro
BURMAKIN, Mikhail, YAO SHI, HEDSTRÖM, Elisabeth, KOGNER, Per, SELIVANOVA, Galina
Published in Clinical cancer research (15.09.2013)
Published in Clinical cancer research (15.09.2013)
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MDM2-Dependent Downregulation of p21 and hnRNP K Provides a Switch between Apoptosis and Growth Arrest Induced by Pharmacologically Activated p53
Enge, Martin, Bao, Wenjie, Hedström, Elisabeth, Jackson, Stephen P., Moumen, Abdeladim, Selivanova, Galina
Published in Cancer cell (03.03.2009)
Published in Cancer cell (03.03.2009)
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The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair
Henriksson, Sofia, Rassoolzadeh, Hanif, Hedström, Elisabeth, Coucoravas, Christos, Julner, Alexander, Goldstein, Michael, Imreh, Gabriela, Zhivotovsky, Boris, Kastan, Michael B, Helleday, Thomas, Farnebo, Marianne
Published in Genes & development (15.12.2014)
Published in Genes & development (15.12.2014)
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Tumor-specific induction of apoptosis by a p53-reactivating compound
Hedström, Elisabeth, Issaeva, Natalia, Enge, Martin, Selivanova, Galina
Published in Experimental cell research (01.02.2009)
Published in Experimental cell research (01.02.2009)
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Editor's Note: Dual Targeting of Wild-Type and Mutant p53 by Small-molecule RITA Results in the Inhibition of N-Myc and Key Survival Oncogenes and Kills Neuroblastoma Cells In Vivo and In Vitro
Burmakin, Mikhail, Shi, Yao, Hedström, Elisabeth, Kogner, Per, Selivanova, Galina
Published in Clinical cancer research (01.09.2021)
Published in Clinical cancer research (01.09.2021)
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Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small Molecule
Grinkevich, Vera V, Vema, Aparna, Fawkner, Karin, Issaeva, Natalia, Andreotti, Virginia, Dickinson, Eleanor R, Hedström, Elisabeth, Spinnler, Clemens, Inga, Alberto, Larsson, Lars-Gunnar, Karlén, Anders, Wilhelm, Margareta, Barran, Perdita E, Okorokov, Andrei L, Selivanova, Galina, Zawacka-Pankau, Joanna E
Published in Frontiers in molecular biosciences (01.06.2022)
Published in Frontiers in molecular biosciences (01.06.2022)
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Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX
Spinnler, C, Hedström, E, Li, H, de Lange, J, Nikulenkov, F, Teunisse, A F A S, Verlaan-de Vries, M, Grinkevich, V, Jochemsen, A G, Selivanova, G
Published in Cell death and differentiation (01.11.2011)
Published in Cell death and differentiation (01.11.2011)
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MDM2-Dependent Downregulation of p21 and hnRNP K Provides a Switch between Apoptosis and Growth Arrest Induced by Pharmacologically Activated p53
Enge, Martin, Bao, Wenjie, Hedström, Elisabeth, Jackson, Stephen P., Moumen, Abdeladim, Selivanova, Galina
Published in Cancer cell (07.07.2009)
Published in Cancer cell (07.07.2009)
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Research Article: Tumor-specific induction of apoptosis by a p53-reactivating compound
Hedstrom, Elisabeth, Issaeva, Natalia, Enge, Martin, Selivanova, Galina
Published in Experimental cell research (01.02.2009)
Published in Experimental cell research (01.02.2009)
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Novel allosteric mechanism of dual p53/MDM2 and p53/MDM4 inhibition by a small molecule
Grinkevich, Vera, Vema Aparna, Fawkner, Karin, Issaeva, Natalia, Andreotti, Virginia, Dickinson, Eleanor R, Hedstrom, Elisabeth, Spinnler, Clemens, Inga, Alberto, Larsson, Lars-Gunnar, Karlen, Anders, Wilhelm, Margareta, Barran, Perdita, Okorokov, Andrei, Selivanova, Galina, Zawacka-Pankau, Joanna Elzbieta
Published in bioRxiv (24.12.2021)
Published in bioRxiv (24.12.2021)
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Novel allosteric mechanism of p53 activation by small molecules for targeted anticancer therapy
Zawacka-Pankau, Joanna, Grinkevich, Vera V, Burmakin, Mikhail, Vema, Aparna, Fawkner, Karin, Issaeva, Natalia, Andreotti, Virginia, Dickinson, Eleanor R, Hedstrom, Elisabeth, Spinnler, Clemens, Inga, Alberto, Larsson, Lars-Gunnar, Karlen, Anders, Tarasova, Olga, Poroikov, Vladimir, Lavrenov, Sergey, Preobrazhenskaya, Maria, Barran, Perdita E, Okorokov, Andrei L, Selivanova, Galina
Published in bioRxiv (07.12.2018)
Published in bioRxiv (07.12.2018)
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