Initial structure-activity relationships of lysophosphatidic acid receptor antagonists: discovery of a high-affinity LPA1/LPA3 receptor antagonist
HEASLEY, Brian H, JAROSZ, Renata, LYNCH, Kevin R, MACDONALD, Timothy L
Published in Bioorganic & medicinal chemistry letters (07.06.2004)
Published in Bioorganic & medicinal chemistry letters (07.06.2004)
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Identification of Clinical Candidate M2698, a Dual p70S6K and Akt Inhibitor, for Treatment of PAM Pathway-Altered Cancers
DeSelm, Lizbeth, Huck, Bayard, Lan, Ruoxi, Neagu, Constantin, Potnick, Justin, Xiao, Yufang, Chen, Xiaoling, Jones, Reinaldo, Richardson, Thomas E, Heasley, Brian H, Haxell, Thomas, Moore, Joseph, Tian, Hui, Georgi, Katrin, Rohdich, Felix, Sutton, Amanda, Johnson, Theresa, Mochalkin, Igor, Jackson, Jennifer, Lin, Jing, Crowley, Lindsey, Machl, Andreas, Clark, Anderson, Wilker, Erik, Sherer, Brian, Goutopoulos, Andreas
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Published in Journal of medicinal chemistry (14.10.2021)
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A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA3 receptor-selective antagonist
Heasley, Brian H, Jarosz, Renata, Carter, Karen M, Van, S Jenny, Lynch, Kevin R, Macdonald, Timothy L
Published in Bioorganic & medicinal chemistry letters (02.08.2004)
Published in Bioorganic & medicinal chemistry letters (02.08.2004)
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Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acid
Santos, Webster L., Heasley, Brian H., Jarosz, Renata, Carter, Karen M., Lynch, Kevin R., Macdonald, Timothy L.
Published in Bioorganic & medicinal chemistry letters (05.07.2004)
Published in Bioorganic & medicinal chemistry letters (05.07.2004)
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Discovery of substituted benzamides as follicle stimulating hormone receptor allosteric modulators
Yu, Henry N., Richardson, Thomas E., Nataraja, Selva, Fischer, David J., Sriraman, Venkataraman, Jiang, Xuliang, Bharathi, Pandi, Foglesong, Robert J., Haxell, Thomas F.N., Heasley, Brian H., Jenks, Mathew, Li, Jane, Dugas, Melanie S., Collis, Regina, Tian, Hui, Palmer, Stephen, Goutopoulos, Andreas
Published in Bioorganic & medicinal chemistry letters (01.05.2014)
Published in Bioorganic & medicinal chemistry letters (01.05.2014)
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Synthesis and biological evaluation of antifungal derivatives of enfumafungin as orally bioavailable inhibitors of β-1,3-glucan synthase
Heasley, Brian H., Pacofsky, Gregory J., Mamai, Ahmed, Liu, Hao, Nelson, Kingsley, Coti, Ghjuvanni, Peel, Michael R., Balkovec, James M., Greenlee, Mark L., Liberator, Paul, Meng, Dongfang, Parker, Dann L., Wilkening, Robert R., Apgar, James M., Racine, F., Hsu, Ming Jo, Giacobbe, Robert A., Kahn, Jennifer Nielsen
Published in Bioorganic & medicinal chemistry letters (15.11.2012)
Published in Bioorganic & medicinal chemistry letters (15.11.2012)
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In Vitro Metabolism of 2-Acetylbenzothiophene: Relevance to Zileuton Hepatotoxicity
Joshi, Elizabeth M, Heasley, Brian H, Chordia, Mahendra D, Macdonald, Timothy L
Published in Chemical research in toxicology (01.02.2004)
Published in Chemical research in toxicology (01.02.2004)
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NOVEL METHODS FOR SYNTHESIZING ENANTIOPURE (S)-METHADONE, (R)-METHADONE, RACEMIC (R,S)-METHADONE AND RELATED ANALOGUE SUBSTANCES
Manfredi, Paolo L, Mattarei, Andrea, Banzato, Marco, Ongaro, Alberto, Heasley, Brian H, Inturrisi, Charles E, Furlan, Alberto, Tucker, Zachary D
Year of Publication 04.07.2024
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Year of Publication 04.07.2024
Patent
Initial structure–activity relationships of lysophosphatidic acid receptor antagonists: discovery of a high-affinity LPA 1/LPA 3 receptor antagonist
Heasley, Brian H., Jarosz, Renata, Lynch, Kevin R., Macdonald, Timothy L.
Published in Bioorganic & medicinal chemistry letters (2004)
Published in Bioorganic & medicinal chemistry letters (2004)
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Journal Article
NOVEL METHODS FOR SYNTHETIZING ENANTIOPURE (S)-METHADONE, (R)-METHADONE, RACEMIC (R,S)-METHADONE AND RELATED ANALOGUE SUBSTANCES
MATTAREI, Andrea, INTURRISI, Charles, E, BANZATO, Marco, ONGARO, Alberto, FURLAN, Alberto, MANFREDI, Paolo, L, HEASLEY, Brian, H, TUCKER, Zachary, D
Year of Publication 14.02.2024
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Year of Publication 14.02.2024
Patent
A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA3receptor-selective antagonist
HEASLEY, Brian H, JAROSZ, Renata, CARTER, Karen M, VAN, S. Jenny, LYNCH, Kevin R, MACDONALD, Timothy L
Published in Bioorganic & medicinal chemistry letters (2004)
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Published in Bioorganic & medicinal chemistry letters (2004)
Journal Article
A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA 3 receptor-selective antagonist
Heasley, Brian H, Jarosz, Renata, Carter, Karen M, Jenny Van, S, Lynch, Kevin R, Macdonald, Timothy L
Published in Bioorganic & medicinal chemistry letters (2004)
Published in Bioorganic & medicinal chemistry letters (2004)
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Journal Article
NOVEL METHODS FOR SYNTHETIZING ENANTIOPURE (S)-METHADONE, (R)-METHADONE, RACEMIC (R,S)-METHADONE AND RELATED ANALOGUE SUBSTANCES
FURLAN, ALBERTO, TUCKER, ZACHARY D, INTURRISI, CHARLES E, HEASLEY, BRIAN H, ONGARO, ALBERTO, BANZATO, MARCO, MATTAREI, ANDREA, MANFREDI, PAOLO L
Year of Publication 13.10.2022
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Year of Publication 13.10.2022
Patent