Thymoquinone ameliorates diabetic phenotype in Diet-Induced Obesity mice via activation of SIRT-1-dependent pathways
Karandrea, Shpetim, Yin, Huquan, Liang, Xiaomei, Slitt, Angela L, Heart, Emma A
Published in PloS one (26.09.2017)
Published in PloS one (26.09.2017)
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Thymoquinone, a bioactive component of Nigella sativa, normalizes insulin secretion from pancreatic β-cells under glucose overload via regulation of malonyl-CoA
Gray, Joshua P, Burgos, Delaine Zayasbazan, Yuan, Tao, Seeram, Navindra, Rebar, Rebecca, Follmer, Rebecca, Heart, Emma A
Published in American journal of physiology: endocrinology and metabolism (15.03.2016)
Published in American journal of physiology: endocrinology and metabolism (15.03.2016)
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Journal Article
NAD(P)H-dependent quinone oxidoreductase 1 (NQO1) and cytochrome P450 oxidoreductase (CYP450OR) differentially regulate menadione-mediated alterations in redox status, survival and metabolism in pancreatic β-cells
Gray, Joshua P., Karandrea, Shpetim, Burgos, Delaine Zayasbazan, Jaiswal, Anil A, Heart, Emma A.
Published in Toxicology letters (16.11.2016)
Published in Toxicology letters (16.11.2016)
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Mechanisms of Doxorubicin Toxicity in Pancreatic β-Cells
Heart, Emma A, Karandrea, Shpetim, Liang, Xiaomei, Balke, Maren E, Beringer, Patrick A, Bobczynski, Elyse M, Zayas-Bazán Burgos, Delaine, Richardson, Tiffany, Gray, Joshua P
Published in Toxicological sciences (01.08.2016)
Published in Toxicological sciences (01.08.2016)
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Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells
Peyot, Marie-Line, Gray, Joshua P, Lamontagne, Julien, Smith, Peter J S, Holz, George G, Madiraju, S R Murthy, Prentki, Marc, Heart, Emma
Published in PloS one (13.07.2009)
Published in PloS one (13.07.2009)
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β-Cell Mitochondria Exhibit Membrane Potential Heterogeneity That Can Be Altered by Stimulatory or Toxic Fuel Levels
WIKSTROM, Jakob D, KATZMAN, Shana M, COLLINS, Sheila, SHIRIHAI, Orian S, MOHAMED, Hibo, TWIG, Gilad, GRAF, Solomon A, HEART, Emma, MOLINA, Anthony J. A, CORKEY, Barbara E, MOITOSO DE VARGAS, Lina, DANIAL, Nika N
Published in Diabetes (New York, N.Y.) (01.10.2007)
Published in Diabetes (New York, N.Y.) (01.10.2007)
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Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion
Heart, Emma, Cline, Gary W, Collis, Leon P, Pongratz, Rebecca L, Gray, Joshua P, Smith, Peter J. S
Published in American journal of physiology: endocrinology and metabolism (01.06.2009)
Published in American journal of physiology: endocrinology and metabolism (01.06.2009)
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Glucosamine-induced insulin resistance in 3T3-L1 adipocytes
Heart, Emma, Choi, Woo S, Sung, Chin K
Published in American journal of physiology: endocrinology and metabolism (01.01.2000)
Published in American journal of physiology: endocrinology and metabolism (01.01.2000)
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Journal Article
Thymoquinone, a bioactive component of Nigella sativa, normalizes insulin secretion from pancreatic [Beta]-cells under glucose overload via regulation of malonyl-CoA
Gray, Joshua P, Burgos, Delaine Zayasbazan, Yuan, Tao, Seeram, Navindra, Rebar, Rebecca, Follmer, Rebecca, Heart, Emma A
Published in American journal of physiology: endocrinology and metabolism (15.03.2016)
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Published in American journal of physiology: endocrinology and metabolism (15.03.2016)
Journal Article
Synchronizing Ca2+ and cAMP oscillations in pancreatic beta-cells: a role for glucose metabolism and GLP-1 receptors? Focus on "regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach"
Holz, George G, Heart, Emma, Leech, Colin A
Published in American Journal of Physiology: Cell Physiology (01.01.2008)
Published in American Journal of Physiology: Cell Physiology (01.01.2008)
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