4D analysis of malaria parasite invasion offers insights into erythrocyte membrane remodeling and parasitophorous vacuole formation
Geoghegan, Niall D., Evelyn, Cindy, Whitehead, Lachlan W., Pasternak, Michal, McDonald, Phoebe, Triglia, Tony, Marapana, Danushka S., Kempe, Daryan, Thompson, Jennifer K., Mlodzianoski, Michael J., Healer, Julie, Biro, Maté, Cowman, Alan F., Rogers, Kelly L.
Published in Nature communications (15.06.2021)
Published in Nature communications (15.06.2021)
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Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle
Favuzza, Paola, de Lera Ruiz, Manuel, Thompson, Jennifer K., Triglia, Tony, Ngo, Anna, Steel, Ryan W.J., Vavrek, Marissa, Christensen, Janni, Healer, Julie, Boyce, Christopher, Guo, Zhuyan, Hu, Mengwei, Khan, Tanweer, Murgolo, Nicholas, Zhao, Lianyun, Penington, Jocelyn Sietsma, Reaksudsan, Kitsanapong, Jarman, Kate, Dietrich, Melanie H., Richardson, Lachlan, Guo, Kai-Yuan, Lopaticki, Sash, Tham, Wai-Hong, Rottmann, Matthias, Papenfuss, Tony, Robbins, Jonathan A., Boddey, Justin A., Sleebs, Brad E., Sabroux, Hélène Jousset, McCauley, John A., Olsen, David B., Cowman, Alan F.
Published in Cell host & microbe (08.04.2020)
Published in Cell host & microbe (08.04.2020)
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Development and validation of serological markers for detecting recent Plasmodium vivax infection
Longley, Rhea J., White, Michael T., Takashima, Eizo, Brewster, Jessica, Morita, Masayuki, Harbers, Matthias, Obadia, Thomas, Robinson, Leanne J., Matsuura, Fumie, Liu, Zoe S. J., Li-Wai-Suen, Connie S. N., Tham, Wai-Hong, Healer, Julie, Huon, Christele, Chitnis, Chetan E., Nguitragool, Wang, Monteiro, Wuelton, Proietti, Carla, Doolan, Denise L., Siqueira, Andre M., Ding, Xavier C., Gonzalez, Iveth J., Kazura, James, Lacerda, Marcus, Sattabongkot, Jetsumon, Tsuboi, Takafumi, Mueller, Ivo
Published in Nature Medicine (01.05.2020)
Published in Nature Medicine (01.05.2020)
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Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA
Chen, Lin, Xu, Yibin, Wong, Wilson, Thompson, Jennifer K, Healer, Julie, Goddard-Borger, Ethan D, Lawrence, Michael C, Cowman, Alan F
Published in eLife (14.02.2017)
Published in eLife (14.02.2017)
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Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex
Wong, Wilson, Huang, Rick, Menant, Sebastien, Hong, Chuan, Sandow, Jarrod J., Birkinshaw, Richard W., Healer, Julie, Hodder, Anthony N., Kanjee, Usheer, Tonkin, Christopher J., Heckmann, Denise, Soroka, Vladislav, Søgaard, Teit Max Moscote, Jørgensen, Thomas, Duraisingh, Manoj T., Czabotar, Peter E., de Jongh, Willem A., Tham, Wai-Hong, Webb, Andrew I., Yu, Zhiheng, Cowman, Alan F.
Published in Nature (London) (01.01.2019)
Published in Nature (London) (01.01.2019)
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Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development
França, Camila Tenorio, White, Michael T, He, Wen-Qiang, Hostetler, Jessica B, Brewster, Jessica, Frato, Gabriel, Malhotra, Indu, Gruszczyk, Jakub, Huon, Christele, Lin, Enmoore, Kiniboro, Benson, Yadava, Anjali, Siba, Peter, Galinski, Mary R, Healer, Julie, Chitnis, Chetan, Cowman, Alan F, Takashima, Eizo, Tsuboi, Takafumi, Tham, Wai-Hong, Fairhurst, Rick M, Rayner, Julian C, King, Christopher L, Mueller, Ivo
Published in eLife (26.09.2017)
Published in eLife (26.09.2017)
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Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker development
Richards, Jack S, Arumugam, Thangavelu U, Reiling, Linda, Healer, Julie, Hodder, Anthony N, Fowkes, Freya J I, Cross, Nadia, Langer, Christine, Takeo, Satoru, Uboldi, Alex D, Thompson, Jennifer K, Gilson, Paul R, Coppel, Ross L, Siba, Peter M, King, Christopher L, Torii, Motomi, Chitnis, Chetan E, Narum, David L, Mueller, Ivo, Crabb, Brendan S, Cowman, Alan F, Tsuboi, Takafumi, Beeson, James G
Published in The Journal of immunology (1950) (15.07.2013)
Published in The Journal of immunology (1950) (15.07.2013)
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Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes
Chen, Lin, Xu, Yibin, Healer, Julie, Thompson, Jenny K, Smith, Brian J, Lawrence, Michael C, Cowman, Alan F
Published in eLife (08.10.2014)
Published in eLife (08.10.2014)
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A Next-generation Genetically Attenuated Plasmodium falciparum Parasite Created by Triple Gene Deletion
Mikolajczak, Sebastian A, Lakshmanan, Viswanathan, Fishbaugher, Matthew, Camargo, Nelly, Harupa, Anke, Kaushansky, Alexis, Douglass, Alyse N, Baldwin, Michael, Healer, Julie, O'Neill, Matthew, Phuong, Thuan, Cowman, Alan, Kappe, Stefan H I
Published in Molecular therapy (01.09.2014)
Published in Molecular therapy (01.09.2014)
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Reticulocyte-binding protein homologue 5 – An essential adhesin involved in invasion of human erythrocytes by Plasmodium falciparum
Baum, Jake, Chen, Lin, Healer, Julie, Lopaticki, Sash, Boyle, Michelle, Triglia, Tony, Ehlgen, Florian, Ralph, Stuart A., Beeson, James G., Cowman, Alan F.
Published in International journal for parasitology (01.02.2009)
Published in International journal for parasitology (01.02.2009)
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Naturally acquired antibody kinetics against Plasmodium vivax antigens in people from a low malaria transmission region in western Thailand
Liu, Zoe Shih-Jung, Sattabongkot, Jetsumon, White, Michael, Chotirat, Sadudee, Kumpitak, Chalermpon, Takashima, Eizo, Harbers, Matthias, Tham, Wai-Hong, Healer, Julie, Chitnis, Chetan E, Tsuboi, Takafumi, Mueller, Ivo, Longley, Rhea J
Published in BMC medicine (09.03.2022)
Published in BMC medicine (09.03.2022)
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Kinetic Flux Profiling Elucidates Two Independent Acetyl-CoA Biosynthetic Pathways in Plasmodium falciparum
Cobbold, Simon A., Vaughan, Ashley M., Lewis, Ian A., Painter, Heather J., Camargo, Nelly, Perlman, David H., Fishbaugher, Matthew, Healer, Julie, Cowman, Alan F., Kappe, Stefan H.I., Llinás, Manuel
Published in The Journal of biological chemistry (20.12.2013)
Published in The Journal of biological chemistry (20.12.2013)
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A comparison of non-magnetic and magnetic beads for measuring IgG antibodies against Plasmodium vivax antigens in a multiplexed bead-based assay using Luminex technology (Bio-Plex 200 or MAGPIX)
Mazhari, Ramin, Brewster, Jessica, Fong, Rich, Bourke, Caitlin, Liu, Zoe S J, Takashima, Eizo, Tsuboi, Takafumi, Tham, Wai-Hong, Harbers, Matthias, Chitnis, Chetan, Healer, Julie, Ome-Kaius, Maria, Sattabongkot, Jetsumon, Kazura, James, Robinson, Leanne J, King, Christopher, Mueller, Ivo, Longley, Rhea J
Published in PloS one (04.12.2020)
Published in PloS one (04.12.2020)
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Reticulocyte and Erythrocyte Binding-Like Proteins Function Cooperatively in Invasion of Human Erythrocytes by Malaria Parasites
Lopaticki, Sash, Maier, Alexander G, Thompson, Jennifer, Wilson, Danny W, Tham, Wai-Hong, Triglia, Tony, Gout, Alex, Speed, Terence P, Beeson, James G, Healer, Julie, Cowman, Alan F
Published in Infection and Immunity (01.03.2011)
Published in Infection and Immunity (01.03.2011)
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A Conserved Molecular Motor Drives Cell Invasion and Gliding Motility across Malaria Life Cycle Stages and Other Apicomplexan Parasites
Baum, Jake, Richard, Dave, Healer, Julie, Rug, Melanie, Krnajski, Zita, Gilberger, Tim-Wolf, Green, Judith L., Holder, Anthony A., Cowman, Alan F.
Published in The Journal of biological chemistry (24.02.2006)
Published in The Journal of biological chemistry (24.02.2006)
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First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers
Spring, Michele, Murphy, Jittawadee, Nielsen, Robin, Dowler, Megan, Bennett, Jason W, Zarling, Stasya, Williams, Jack, de la Vega, Patricia, Ware, Lisa, Komisar, Jack, Polhemus, Mark, Richie, Thomas L, Epstein, Judy, Tamminga, Cindy, Chuang, Ilin, Richie, Nancy, O’Neil, Michael, Heppner, D. Gray, Healer, Julie, O’Neill, Matthew, Smithers, Hannah, Finney, Olivia C, Mikolajczak, Sebastian A, Wang, Ruobing, Cowman, Alan, Ockenhouse, Christian, Krzych, Urszula, Kappe, Stefan H.I
Published in Vaccine (09.10.2013)
Published in Vaccine (09.10.2013)
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Molecular profiling reveals features of clinical immunity and immunosuppression in asymptomatic P. falciparum malaria
Studniberg, Stephanie I, Ioannidis, Lisa J, Utami, Retno A S, Trianty, Leily, Liao, Yang, Abeysekera, Waruni, Li‐Wai‐Suen, Connie S N, Pietrzak, Halina M, Healer, Julie, Puspitasari, Agatha M, Apriyanti, Dwi, Coutrier, Farah, Poespoprodjo, Jeanne R, Kenangalem, Enny, Andries, Benediktus, Prayoga, Pak, Sariyanti, Novita, Smyth, Gordon K, Cowman, Alan F, Price, Ric N, Noviyanti, Rintis, Shi, Wei, Garnham, Alexandra L, Hansen, Diana S
Published in Molecular systems biology (01.04.2022)
Published in Molecular systems biology (01.04.2022)
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Epitope-coated polymer particles elicit neutralising antibodies against Plasmodium falciparum sporozoites
Evert, Benjamin J., Chen, Shuxiong, McConville, Robyn, Steel, Ryan W. J., Healer, Julie, Boddey, Justin A., Huntimer, Lucas, Rehm, Bernd H. A.
Published in npj vaccines (29.11.2021)
Published in npj vaccines (29.11.2021)
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Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical Malaria
He, Wen-Qiang, Shakri, Ahmad Rushdi, Bhardwaj, Rukmini, França, Camila T, Stanisic, Danielle I, Healer, Julie, Kiniboro, Benson, Robinson, Leanne J, Guillotte-Blisnick, Micheline, Huon, Christèle, Siba, Peter, Cowman, Alan, King, Christopher L, Tham, Wai-Hong, Chitnis, Chetan E, Mueller, Ivo
Published in PLoS neglected tropical diseases (01.02.2019)
Published in PLoS neglected tropical diseases (01.02.2019)
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