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Published in Journal of medicinal chemistry (23.08.2012)
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Published in Science (American Association for the Advancement of Science) (18.07.2003)
Published in Science (American Association for the Advancement of Science) (18.07.2003)
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Discovery of 2‑[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia
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Published in Journal of medicinal chemistry (22.05.2014)
Published in Journal of medicinal chemistry (22.05.2014)
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Metal Impurities Cause False Positives in High-Throughput Screening Campaigns
Hermann, Johannes C, Chen, Yingsi, Wartchow, Charles, Menke, John, Gao, Lin, Gleason, Shelley K, Haynes, Nancy-Ellen, Scott, Nathan, Petersen, Ann, Gabriel, Stephen, Vu, Binh, George, Kelly M, Narayanan, Arjun, Li, Shirley H, Qian, Hong, Beatini, Nanda, Niu, Linghao, Gan, Qing-Fen
Published in ACS medicinal chemistry letters (14.02.2013)
Published in ACS medicinal chemistry letters (14.02.2013)
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Discovery, Structure−Activity Relationships, Pharmacokinetics, and Efficacy of Glucokinase Activator (2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675)
Haynes, Nancy-Ellen, Corbett, Wendy L, Bizzarro, Fred T, Guertin, Kevin R, Hilliard, Darryl W, Holland, George W, Kester, Robert F, Mahaney, Paige E, Qi, Lida, Spence, Cheryl L, Tengi, John, Dvorozniak, Mark T, Railkar, Aruna, Matschinsky, Franz M, Grippo, Joseph F, Grimsby, Joseph, Sarabu, Ramakanth
Published in Journal of medicinal chemistry (13.05.2010)
Published in Journal of medicinal chemistry (13.05.2010)
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Discovery of camphor-derived pyrazolones as 11β-hydroxysteroid dehydrogenase type 1 inhibitors
Gillespie, Paul, Pietranico-Cole, Sherrie, Myers, Michael, Bilotta, Joseph A., Conde-Knape, Karin, Fotouhi, Nader, Goodnow, Robert A., Guertin, Kevin R., Hamilton, Matthew M., Haynes, Nancy-Ellen, Liu, Baolian, Qi, Lida, Ren, Yonglin, Scott, Nathan R., So, Sung-Sau, Spence, Cheryl, Taub, Rebecca, Thakkar, Kshitij, Tilley, Jefferson W., Zwingelstein, Catherine
Published in Bioorganic & medicinal chemistry letters (15.06.2014)
Published in Bioorganic & medicinal chemistry letters (15.06.2014)
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Identification of an Adamantyl Azaquinolone JNK Selective Inhibitor
Haynes, Nancy-Ellen, Scott, Nathan R, Chen, Li C, Janson, Cheryl A, Li, Jia Kui, Lukacs, Christine M, Railkar, Aruna, Tozzo, Effie, Whittard, Toni, Brown, Nicholas F, Cheung, Adrian Wai-Hing
Published in ACS medicinal chemistry letters (13.09.2012)
Published in ACS medicinal chemistry letters (13.09.2012)
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Identification of RO4597014, a Glucokinase Activator Studied in the Clinic for the Treatment of Type 2 Diabetes
Qian, Yimin, Corbett, Wendy L, Berthel, Steven J, Choi, Duk Soon, Dvorozniak, Mark T, Geng, Wanping, Gillespie, Paul, Guertin, Kevin R, Haynes, Nancy-Ellen, Kester, Robert F, Mennona, Francis A, Moore, David, Racha, Jagdish, Radinov, Roumen, Sarabu, Ramakanth, Scott, Nathan R, Grimsby, Joseph, Mallalieu, Navita L
Published in ACS medicinal chemistry letters (11.04.2013)
Published in ACS medicinal chemistry letters (11.04.2013)
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YI LIN, SCOTT NATHAN ROBERT, HAYNES NANCY ELLEN, ZAK MARK, KIM KYUNGJIN, HERMANN JOHANNES CORNELIUS
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Boger, Dale L., Haynes, Nancy-Ellen, Kitos, Paul A., Warren, Mark S., Ramcharan, Joseph, Marolewski, Ariane E., Benkovic, Stephen J.
Published in Bioorganic & medicinal chemistry (01.09.1997)
Published in Bioorganic & medicinal chemistry (01.09.1997)
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Functionalized analogues of 5,8,10-trideazafolate as potential inhibitors of GAR Tfase or AICAR Tfase
Boger, Dale L., Haynes, Nancy-Ellen, Warren, Mark S., Gooljarsingh, Lata T., Ramcharan, Joseph, Kitos, Paul A., Benkovic, Stephen J.
Published in Bioorganic & medicinal chemistry (01.09.1997)
Published in Bioorganic & medicinal chemistry (01.09.1997)
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Functionalized analogues of 5,8,10-trideazafolate: Development of an enzyme-assembled tight binding inhibitor of GAR Tfase and a potential irreversible inhibitor of AICAR Tfase
Boger, Dale L., Haynes, Nancy-Ellen, Warren, Mark S., Ramcharan, Joseph, Kitos, Paul A., Benkovic, Stephen J.
Published in Bioorganic & medicinal chemistry (01.09.1997)
Published in Bioorganic & medicinal chemistry (01.09.1997)
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AMINOMETHYL QUINOLONE COMPOUNDS
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Year of Publication 02.05.2014
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Year of Publication 20.09.2012
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Multisubstrate analogue based on 5,8,10-trideazafolate
Boger, Dale L., Haynes, Nancy-Ellen, Warren, Mark S., Ramcharan, Joseph, Kitos, Paul A., Benkovic, Stephen J.
Published in Bioorganic & medicinal chemistry (01.09.1997)
Published in Bioorganic & medicinal chemistry (01.09.1997)
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Abenzyl 10-formyl-trideazafolic acid (abenzyl 10-formyl-TDAF): An effective inhibitor of glycinamide ribonucleotide transformylase
Boger, Dale L., Haynes, Nancy-Ellen, Warren, Mark S., Ramcharan, Joseph, Marolewski, Ariane E., Kitos, Paul A., Benkovic, Stephen J.
Published in Bioorganic & medicinal chemistry (01.09.1997)
Published in Bioorganic & medicinal chemistry (01.09.1997)
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PYRIDAZINONE GLUCOKINASE ACTIVATORS
SCOTT NATHAN ROBERT, HAYNES NANCY ELLEN, TILLEY JEFFERSON WRIGHT, QIAN YIMIN, MCDERMOTT LEE APOSTLE, SARABU RAMAKANTH, KESTER ROBERT FRANCIS, BERTHEL STEVEN JOSEPH
Year of Publication 26.11.2010
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Year of Publication 26.11.2010
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