Small-Sized Human Immunodeficiency Virus Type-1 Protease Inhibitors Containing Allophenylnorstatine to Explore the S2′ Pocket
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Published in Journal of medicinal chemistry (10.12.2009)
Published in Journal of medicinal chemistry (10.12.2009)
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Hayashi, Yoshio, Regnier, Thomas, Nishiguchi, Shigenobu, Sydnes, Magne O., Hashimoto, Daisuke, Hasegawa, Junya, Katoh, Takahiro, Kajimoto, Tetsuya, Shiozuka, Masataka, Matsuda, Ryoichi, Node, Manabu, Kiso, Yoshiaki
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Published in Chemical communications (Cambridge, England) (28.05.2008)
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An Overview of Severe Acute Respiratory Syndrome–Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy
Pillaiyar, Thanigaimalai, Manickam, Manoj, Namasivayam, Vigneshwaran, Hayashi, Yoshio, Jung, Sang-Hun
Published in Journal of Medicinal Chemistry (28.07.2016)
Published in Journal of Medicinal Chemistry (28.07.2016)
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Suzue, Naoto, Nikawa, Takeshi, Onishi, Yuko, Yamada, Chiharu, Hirasaka, Katsuya, Ogawa, Takayuki, Furochi, Harumi, Kosaka, Hirofumi, Ishidoh, Kazumi, Gu, Hua, Takeda, Shin'ichi, Ishimaru, Naozumi, Hayashi, Yoshio, Yamamoto, Hironori, Kishi, Kyoichi, Yasui, Natsuo
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Published in Journal of bone and mineral research (01.05.2006)
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ON intramolecular acyl migration reaction in the development of prodrugs and the synthesis of difficult sequence-containing bioactive peptides
Sohma, Youhei, Hayashi, Yoshio, Skwarczynski, Mariusz, Hamada, Yoshio, Sasaki, Masato, Kimura, Tooru, Kiso, Yoshiaki
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Published in Biopolymers (2004)
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Synthesis and activity of tetrapeptidic HTLV-I protease inhibitors possessing different P3-cap moieties
MEIHUI ZHANG, NGUYEN, Jeffrey-Tri, KUMADA, Henri-Obadja, KIMURA, Tooru, MAOSHENG CHENG, HAYASHI, Yoshio, KISO, Yoshiaki
Published in Bioorganic & medicinal chemistry (15.05.2008)
Published in Bioorganic & medicinal chemistry (15.05.2008)
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Truncation and non-natural amino acid substitution studies on HTLV-I protease hexapeptidic inhibitors
Nguyen, Jeffrey-Tri, Zhang, Meihui, Kumada, Henri-Obadja, Itami, Ayako, Nishiyama, Keiji, Kimura, Tooru, Cheng, Maosheng, Hayashi, Yoshio, Kiso, Yoshiaki
Published in Bioorganic & medicinal chemistry (2008)
Published in Bioorganic & medicinal chemistry (2008)
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Role of Plasmacytoid Dendritic Cells for Aberrant Class II Expression in Exocrine Glands from Estrogen-Deficient Mice of Healthy Background
Arakaki, Rieko, Nagaoka, Ai, Ishimaru, Naozumi, Yamada, Akiko, Yoshida, Satoko, Hayashi, Yoshio
Published in The American journal of pathology (01.05.2009)
Published in The American journal of pathology (01.05.2009)
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Crystal Growth Procedure of HIV-1 Protease-Inhibitor KNI-272 Complex for Neutron Structural Analysis at 1.9 Å Resolution
Shimizu, Noriko, Sugiyama, Shigeru, Maruyama, Mihoko, Takahashi, Yoshinori, Adachi, Motoyasu, Tamada, Taro, Hidaka, Koushi, Hayashi, Yoshio, Kimura, Tooru, Kiso, Yoshiaki, Adachi, Hiroaki, Takano, Kazufumi, Murakami, Satoshi, Inoue, Tsuyoshi, Kuroki, Ryota, Mori, Yusuke, Matsumura, Hiroyoshi
Published in Crystal growth & design (07.07.2010)
Published in Crystal growth & design (07.07.2010)
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Hayashi, Yoshio, Arakaki, Rieko, Ishimaru, Naozumi
Published in The Journal of Medical Investigation (2009)
Published in The Journal of Medical Investigation (2009)
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KMI-358 and KMI-370, highly potent and small-sized BACE1 inhibitors containing phenylnorstatine
Kimura, Tooru, Shuto, Daisuke, Kasai, Soko, Liu, Ping, Hidaka, Koushi, Hamada, Takashi, Hayashi, Yoshio, Hattori, Chinatsu, Asai, Masashi, Kitazume, Shinobu, Saido, Takaomi C., Ishiura, Shoichi, Kiso, Yoshiaki
Published in Bioorganic & medicinal chemistry letters (22.03.2004)
Published in Bioorganic & medicinal chemistry letters (22.03.2004)
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Synthesis and antiviral property of allophenylnorstatine-based HIV protease inhibitors incorporating D-cysteine derivatives as P2/P3 moieties
AMI, Eiichi, NAKAHARA, Koichiro, SATO, Akihiko, NGUYEN, Jeffrey-Tri, HIDAKA, Koushi, HAMADA, Yoshio, NAKATANI, Shingo, KIMURA, Tooru, HAYASHI, Yoshio, KISO, Yoshiaki
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
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Design and synthesis of BACE1 inhibitors containing a novel norstatine derivative (2 R,3 R)-3-amino-2-hydroxy-4-(phenylthio)butyric acid
Ziora, Zyta, Kasai, Soko, Hidaka, Koushi, Nagamine, Ayaka, Kimura, Tooru, Hayashi, Yoshio, Kiso, Yoshiaki
Published in Bioorganic & medicinal chemistry letters (15.03.2007)
Published in Bioorganic & medicinal chemistry letters (15.03.2007)
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Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome–like autoimmune exocrinopathy
Ishimaru, Naozumi, Arakaki, Rieko, Yoshida, Satoko, Yamada, Akiko, Noji, Sumihare, Hayashi, Yoshio
Published in The Journal of experimental medicine (24.11.2008)
Published in The Journal of experimental medicine (24.11.2008)
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