Search Results - "HAYASE TADAKATSU" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors

Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors

by Suda, Atsushi, Koyano, Hiroshi, Hayase, Tadakatsu, Hada, Kihito, Kawasaki, Ken-ichi, Komiyama, Susumu, Hasegawa, Kiyoshi, Fukami, Takaaki A., Sato, Shigeo, Miura, Takaaki, Ono, Naomi, Yamazaki, Toshikazu, Saitoh, Ryoichi, Shimma, Nobuo, Shiratori, Yasuhiko, Tsukuda, Takuo
Published in Bioorganic & medicinal chemistry letters (15.01.2012)

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Journal Article

Enantioselective synthesis of derivatives and structure–activity relationship study in the development of NA255 as a novel host-targeting anti-HCV agent

Enantioselective synthesis of derivatives and structure–activity relationship study in the development of NA255 as a novel host-targeting anti-HCV agent

by Kawasaki, Ken-ichi, Masubuchi, Miyako, Hayase, Tadakatsu, Komiyama, Susumu, Watanabe, Fumio, Fukuda, Hiroshi, Murata, Takeshi, Matsubara, Yasuaki, Koyama, Kouhei, Shindoh, Hidetoshi, Sakamoto, Hiroshi, Okamato, Kohichi, Ohta, Atsunori, Katsume, Asao, Aoki, Masahiro, Aoki, Yuko, Shimma, Nobuo, Sudoh, Masayuki, Tsukuda, Takuo
Published in Bioorganic & medicinal chemistry letters (01.01.2013)

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Highly Enantioselective Catalytic Asymmetric Automultiplication of Chiral Pyrimidyl Alcohol

Highly Enantioselective Catalytic Asymmetric Automultiplication of Chiral Pyrimidyl Alcohol

by Shibata, Takanori, Morioka, Hiroshi, Hayase, Tadakatsu, Choji, Kaori, Soai, Kenso
Published in Journal of the American Chemical Society (17.01.1996)

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Journal Article

Design, synthesis and antifungal activity of a novel water soluble prodrug of antifungal triazole

Design, synthesis and antifungal activity of a novel water soluble prodrug of antifungal triazole

by Ohwada, Jun, Tsukazaki, Masao, Hayase, Tadakatsu, Oikawa, Nobuhiro, Isshiki, Yoshiaki, Fukuda, Hiroshi, Mizuguchi, Eisaku, Sakaitani, Masahiro, Shiratori, Yasuhiko, Yamazaki, Toshikazu, Ichihara, Shigeyasu, Umeda, Isao, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (01.01.2003)

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Journal Article

tert-뷰톡시카보닐기의 제거 방법

tert-뷰톡시카보닐기의 제거 방법

by KAMAKURA DAIKI, ITO TAISUKE, HAYASE TADAKATSU
Year of Publication 09.09.2024

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Patent

METHOD FOR REMOVING TERT-BUTOXYCARBONYL GROUPS

METHOD FOR REMOVING TERT-BUTOXYCARBONYL GROUPS

by HAYASE, Tadakatsu, KAMAKURA, Daiki, ITO, Taisuke
Year of Publication 13.07.2023

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Patent

Enantioselective synthesis of chiral 5-carbamoyl-3-pyridyl alcohols by asymmetric autocatalytic reaction

Enantioselective synthesis of chiral 5-carbamoyl-3-pyridyl alcohols by asymmetric autocatalytic reaction

by Shibata, Takanori, Morioka, Hiroshi, Tanji, Shigehisa, Hayase, Tadakatsu, Kodaka, Yasutaka, Soai, Kenso
Published in Tetrahedron letters (25.11.1996)

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Journal Article

Highly enantioselective synthesis of a chiral 3-quinolylalkanol by an asymmetric autocatalytic reaction

Highly enantioselective synthesis of a chiral 3-quinolylalkanol by an asymmetric autocatalytic reaction

by Shibata, T, Choji, K, Morioka, H, Hayase, T, Soai, K
Published in Chemical communications (Cambridge, England) (1996)

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Discovery of CH7057288 as an Orally Bioavailable, Selective, and Potent pan-TRK Inhibitor

Discovery of CH7057288 as an Orally Bioavailable, Selective, and Potent pan-TRK Inhibitor

by Ito, Toshiya, Kinoshita, Kazutomo, Tomizawa, Masaki, Shinohara, Shojiro, Nishii, Hiroki, Matsushita, Masayuki, Hattori, Kazuo, Kohchi, Yasunori, Kohchi, Masami, Hayase, Tadakatsu, Watanabe, Fumio, Hasegawa, Kiyoshi, Tanaka, Hiroshi, Kuramoto, Shino, Takanashi, Kenji, Oikawa, Nobuhiro
Published in Journal of medicinal chemistry (22.09.2022)

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Catalytic chirally self-replicating molecule. Asymmetric autocatalytic reaction of a zinc alkoxide of chiral 1-ferrocenyl-2-methylpropan-1-ol

Catalytic chirally self-replicating molecule. Asymmetric autocatalytic reaction of a zinc alkoxide of chiral 1-ferrocenyl-2-methylpropan-1-ol

by Soai, Kenso, Hayase, Tadakatsu, Takai, Kazuhisa
Published in Tetrahedron: asymmetry (01.03.1995)

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Journal Article

산성 작용기의 알킬화 방법

산성 작용기의 알킬화 방법

by EMURA TAKASHI, HAYASE TADAKATSU, NOMURA KENICHI, TSUCHIYA SATOSHI
Year of Publication 04.10.2023

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Patent

Discovery of [5-Amino-1-(2-methyl‑3H‑benzimidazol-5-yl)pyrazol-4-yl]-(1H‑indol-2-yl)methanone (CH5183284/Debio 1347), An Orally Available and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor

Discovery of [5-Amino-1-(2-methyl‑3H‑benzimidazol-5-yl)pyrazol-4-yl]-(1H‑indol-2-yl)methanone (CH5183284/Debio 1347), An Orally Available and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor

by Ebiike, Hirosato, Taka, Naoki, Matsushita, Masayuki, Ohmori, Masayuki, Takami, Kyoko, Hyohdoh, Ikumi, Kohchi, Masami, Hayase, Tadakatsu, Nishii, Hiroki, Morikami, Kenji, Nakanishi, Yoshito, Akiyama, Nukinori, Shindoh, Hidetoshi, Ishii, Nobuya, Isobe, Takehito, Matsuoka, Hiroharu
Published in Journal of medicinal chemistry (08.12.2016)

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Journal Article

Catalytic asymmetric synthesis of chiral diol, bis[2-(1-hydroxyalkyl)-phenyl]ether, an asymmetric autocatalytic reaction

Catalytic asymmetric synthesis of chiral diol, bis[2-(1-hydroxyalkyl)-phenyl]ether, an asymmetric autocatalytic reaction

by Soai, Kenso, Hayase, Tadakatsu, Shimada, Chieko, Isobe, Koichi
Published in Tetrahedron: asymmetry (01.05.1994)

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Journal Article

METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP

METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP

by HAYASE, Tadakatsu, NOMURA, Kenichi, EMURA, Takashi, TSUCHIYA, Satoshi
Year of Publication 14.07.2022

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Patent

Asymmetric synthesis of optically active fluorine-containing alcohols by the catalytic enantioselective alkylation of aldehydes

Asymmetric synthesis of optically active fluorine-containing alcohols by the catalytic enantioselective alkylation of aldehydes

by Hayase, Tadakatsu, Sugiyama, Tadashi, Suzuki, Masanori, Shibata, Takanori, Soai, Kenso
Published in Journal of fluorine chemistry (01.08.1997)

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Journal Article

COMPOUND LIBRARY

COMPOUND LIBRARY

by IIKURA HITOSHI, OGAWA HIROKO, KINOSHITA KAZUHIRO, SAITO MASATO, HAYASE TADAKATSU, NISHIMOTO MASAHIRO, MURATA YOSHIHISA, ORI KAZUTOMO, NOMURA KENICHI, KAMAKURA DAIKI, EMURA TAKESHI, ITO HIROAKI, TSUCHIYA TOMOHITO
Year of Publication 19.07.2023

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Patent

COMPOUND LIBRARY

COMPOUND LIBRARY

by HAYASE, Tadakatsu, NISHIMOTO, Masahiro, SAITO, Masato, KINOSHITA, Kazutomo, TSUCHIYA, Satoshi, NOMURA, Kenichi, EMURA, Takashi, KAMAKURA, Daiki, IIKURA, Hitoshi, ITO, Taisuke, OGAWA, Hiroko, ORI, Kazutomo, MURATA, Yoshihisa
Year of Publication 14.07.2022

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Patent

Abstract 2533: Design and preclinical profile of CH5183284/Debio 1347, a novel orally available and selective FGFR inhibitor acting on a gatekeeper mutant of FGFR2

by Ebiike, Hirosato, Taka, Naoki, Nakanishi, Yoshito, Akiyama, Nukinori, Sawamura, Fumie, Morikami, Kenji, Matsushita, Masayuki, Ohmori, Masayuki, Takami, Kyouko, Hyohdoh, Ikumi, Kohchi, Masami, Hayase, Tadakatsu, Nishii, Hiroki, Ishii, Nobuya, Matsuoka, Hiroharu
Published in Cancer research (Chicago, Ill.) (01.10.2014)

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Journal Article

Asymmetric synthesis of pyrimidyl alkanol without adding chiral substances by the addition of diisopropylzinc to pyrimidine-5-carbaldehyde in conjunction with asymmetric autocatalysis

Asymmetric synthesis of pyrimidyl alkanol without adding chiral substances by the addition of diisopropylzinc to pyrimidine-5-carbaldehyde in conjunction with asymmetric autocatalysis

by Soai, Kenso, Sato, Itaru, Shibata, Takanori, Komiya, Soichiro, Hayashi, Masanobu, Matsueda, Yohei, Imamura, Hikaru, Hayase, Tadakatsu, Morioka, Hiroshi, Tabira, Hayami, Yamamoto, Jun, Kowata, Yasunori
Published in Tetrahedron: asymmetry (17.01.2003)

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Journal Article

An enantioselective Baylis-Hillman reaction catalyzed by chiral phosphines under atmospheric pressure

An enantioselective Baylis-Hillman reaction catalyzed by chiral phosphines under atmospheric pressure

by Hayase, T, Shibata, T, Soai, K, Wakatsuki, Y
Published in Chemical communications (Cambridge, England) (21.06.1998)

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