A Novel HER3-Targeting Antibody-Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization
Hashimoto, Yuuri, Koyama, Kumiko, Kamai, Yasuki, Hirotani, Kenji, Ogitani, Yusuke, Zembutsu, Akiko, Abe, Manabu, Kaneda, Yuki, Maeda, Naoyuki, Shiose, Yoshinobu, Iguchi, Takuma, Ishizaka, Tomomichi, Karibe, Tsuyoshi, Hayakawa, Ichiro, Morita, Koji, Nakada, Takashi, Nomura, Taisei, Wakita, Kenichi, Kagari, Takashi, Abe, Yuki, Murakami, Masato, Ueno, Suguru, Agatsuma, Toshinori
Published in Clinical cancer research (01.12.2019)
Published in Clinical cancer research (01.12.2019)
Get full text
Journal Article
Toward the Synthesis of SB-203207: Construction of Four Contiguous Nitrogen-Containing Stereogenic Centers
Hayakawa, Ichiro, Nagayasu, Anna, Sakakura, Akira
Published in Journal of organic chemistry (06.12.2019)
Published in Journal of organic chemistry (06.12.2019)
Get full text
Journal Article
Quantitative analysis of the Tricholoma ustale-derived toxin, ustalic acid, in mushroom and food samples by LC–MS/MS
Yoshioka, Naoki, Hayakawa, Ichiro, Minatani, Tomiaki, Tomozawa, Junko, Akiyama, Hiroyuki, Yomo, Hiroto
Published in Forensic science international (01.12.2020)
Published in Forensic science international (01.12.2020)
Get full text
Journal Article
Toward the Synthesis of Yuzurimine-Type Alkaloids: Stereoselective Construction of the Heterocyclic Portions of Deoxyyuzurimine and Macrodaphnine
Hayakawa, Ichiro, Nagatani, Ryosuke, Ikeda, Masaki, Yoo, Dong-eun, Saito, Keita, Kigoshi, Hideo, Sakakura, Akira
Published in Organic letters (16.08.2019)
Published in Organic letters (16.08.2019)
Get full text
Journal Article
Enantioselective Diels-Alder Reaction of 3-Nitrocoumarins Promoted by Chiral Organoammonium Salt Catalysts
Fujii, Yudai, Nakao, Ryota, Sugihara, Saki, Fujita, Keita, Araki, Yuya, Kudoh, Takayuki, Hayakawa, Ichiro, Mizoguchi, Haruki, Sakakura, Akira
Published in Synlett (17.12.2020)
Published in Synlett (17.12.2020)
Get more information
Journal Article
Structure-activity relationship studies on an antitumor marine macrolide using aplyronine a-swinholide A hybrid
Ohyoshi, Takayuki, Takano, Atsuhiro, Kikuchi, Imari, Ogura, Tomotaka, Namiki, Mayu, Miyazaki, Yuto, Hirano, Takahiro, Konishi, Shota, Ebihara, Yuta, Takeno, Koichi, Hayakawa, Ichiro, Kigoshi, Hideo
Published in Organic & biomolecular chemistry (06.04.2022)
Published in Organic & biomolecular chemistry (06.04.2022)
Get full text
Journal Article
Dual Inhibition of γ-Tubulin and Plk1 Induces Mitotic Cell Death
Ebisu, Haruna, Shintani, Kana, Chinen, Takumi, Nagumo, Yoko, Shioda, Shuya, Hatanaka, Taisei, Sakakura, Akira, Hayakawa, Ichiro, Kigoshi, Hideo, Usui, Takeo
Published in Frontiers in pharmacology (29.01.2021)
Published in Frontiers in pharmacology (29.01.2021)
Get full text
Journal Article
Development of a novel inducer of protein-protein interactions based on aplyronine A
Ohyoshi, Takayuki, Takano, Atsuhiro, Namiki, Mayu, Ogura, Tomotaka, Miyazaki, Yuto, Ebihara, Yuta, Takeno, Koichi, Hayakawa, Ichiro, Kigoshi, Hideo
Published in Chemical communications (Cambridge, England) (2018)
Published in Chemical communications (Cambridge, England) (2018)
Get full text
Journal Article
Total Synthesis of (−)-13-Oxyingenol and its Natural Derivative
Ohyoshi, Takayuki, Funakubo, Shota, Miyazawa, Yamato, Niida, Keisuke, Hayakawa, Ichiro, Kigoshi, Hideo
Published in Angewandte Chemie International Edition (14.05.2012)
Published in Angewandte Chemie International Edition (14.05.2012)
Get full text
Journal Article
Total Synthesis of Biselide E, a Marine Polyketide
Hayakawa, Ichiro, Suzuki, Kazuaki, Okamura, Masami, Funakubo, Shota, Onozaki, Yuto, Kawamura, Dai, Ohyoshi, Takayuki, Kigoshi, Hideo
Published in Organic letters (20.10.2017)
Published in Organic letters (20.10.2017)
Get full text
Journal Article
Second-generation total synthesis of aplyronine A featuring Ni/Cr-mediated coupling reactions
Hayakawa, Ichiro, Saito, Keita, Matsumoto, Sachiko, Kobayashi, Shinichi, Taniguchi, Ayaka, Kobayashi, Kenichi, Fujii, Yusuke, Kaneko, Takahiro, Kigoshi, Hideo
Published in Organic & biomolecular chemistry (2017)
Published in Organic & biomolecular chemistry (2017)
Get full text
Journal Article
Total Synthesis of Biselide A, A Cytotoxic Macrolide of Marine Origin
Hayakawa, Ichiro, Okamura, Masami, Suzuki, Kazuaki, Shimanuki, Mami, Kimura, Kizuku, Yamada, Takuya, Ohyoshi, Takayuki, Kigoshi, Hideo
Published in Synthesis (Stuttgart) (03.07.2017)
Published in Synthesis (Stuttgart) (03.07.2017)
Get more information
Journal Article
Design, Synthesis, and Biological Evaluations of Aplyronine A–Mycalolide B Hybrid Compound
Kobayashi, Kenichi, Fujii, Yusuke, Hirayama, Yuichiro, Kobayashi, Shinichi, Hayakawa, Ichiro, Kigoshi, Hideo
Published in Organic letters (02.03.2012)
Published in Organic letters (02.03.2012)
Get full text
Journal Article