Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin
DeWaal, Dannielle, Nogueira, Veronique, Terry, Alexander R, Patra, Krushna C, Jeon, Sang-Min, Guzman, Grace, Au, Jennifer, Long, Christopher P, Antoniewicz, Maciek R, Hay, Nissim
Published in Nature communications (31.01.2018)
Published in Nature communications (31.01.2018)
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ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors
Halasi, Marianna, Wang, Ming, Chavan, Tanmay S, Gaponenko, Vadim, Hay, Nissim, Gartel, Andrei L
Published in Biochemical journal (01.09.2013)
Published in Biochemical journal (01.09.2013)
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A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis
Blaha, Catherine S, Ramakrishnan, Gopalakrishnan, Jeon, Sang-Min, Nogueira, Veronique, Rho, Hyunsoo, Kang, Soeun, Bhaskar, Prashanth, Terry, Alexander R, Aissa, Alexandre F, Frolov, Maxim V, Patra, Krushna C, Brooks Robey, R, Hay, Nissim
Published in Nature communications (16.02.2022)
Published in Nature communications (16.02.2022)
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Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer
Patra, Krushna C., Wang, Qi, Bhaskar, Prashanth T., Miller, Luke, Wang, Zebin, Wheaton, Will, Chandel, Navdeep, Laakso, Markku, Muller, William J., Allen, Eric L., Jha, Abhishek K., Smolen, Gromoslaw A., Clasquin, Michelle F., Robey, R. Brooks, Hay, Nissim
Published in Cancer cell (12.08.2013)
Published in Cancer cell (12.08.2013)
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Quantitative Lipid Imaging Reveals a New Signaling Function of Phosphatidylinositol-3,4-Bisphophate: Isoform- and Site-Specific Activation of Akt
Liu, Shu-Lin, Wang, Zhi-Gang, Hu, Yusi, Xin, Yao, Singaram, Indira, Gorai, Sukhamoy, Zhou, Xin, Shim, Yoonjung, Min, Jung-Hyun, Gong, Liang-Wei, Hay, Nissim, Zhang, Jin, Cho, Wonhwa
Published in Molecular cell (20.09.2018)
Published in Molecular cell (20.09.2018)
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FoxOs Inhibit mTORC1 and Activate Akt by Inducing the Expression of Sestrin3 and Rictor
Chen, Chia-Chen, Jeon, Sang-Min, Bhaskar, Prashanth T., Nogueira, Veronique, Sundararajan, Deepa, Tonic, Ivana, Park, Youngkyu, Hay, Nissim
Published in Developmental cell (20.04.2010)
Published in Developmental cell (20.04.2010)
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An important role for Akt3 in platelet activation and thrombosis
O'Brien, Kelly A., Stojanovic-Terpo, Aleksandra, Hay, Nissim, Du, Xiaoping
Published in Blood (13.10.2011)
Published in Blood (13.10.2011)
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Akt Activates the Mammalian Target of Rapamycin by Regulating Cellular ATP Level and AMPK Activity
Hahn-Windgassen, Annett, Nogueira, Veronique, Chen, Chia-Chen, Skeen, Jennifer E., Sonenberg, Nahum, Hay, Nissim
Published in The Journal of biological chemistry (16.09.2005)
Published in The Journal of biological chemistry (16.09.2005)
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Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium
Kerr, Bethany A, West, Xiaoxia Z, Kim, Young-Woong, Zhao, Yongzhong, Tischenko, Miroslava, Cull, Rebecca M, Phares, Timothy W, Peng, Xiao-Ding, Bernier-Latmani, Jeremiah, Petrova, Tatiana V, Adams, Ralf H, Hay, Nissim, Naga Prasad, Sathyamangla V, Byzova, Tatiana V
Published in Nature communications (14.03.2016)
Published in Nature communications (14.03.2016)
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