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Faber, Erik B, Sun, Luxin, Tang, Jian, Roberts, Emily, Ganeshkumar, Sornakala, Wang, Nan, Rasmussen, Damien, Majumdar, Abir, Hirsch, Laura E, John, Kristen, Yang, An, Khalid, Hira, Hawkinson, Jon E, Levinson, Nicholas M, Chennathukuzhi, Vargheese, Harki, Daniel A, Schönbrunn, Ernst, Georg, Gunda I
Published in Nature communications (03.06.2023)
Published in Nature communications (03.06.2023)
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Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model
Pérez Ortiz, Judit M., Mollema, Nissa, Toker, Nicholas, Adamski, Carolyn J., O'Callaghan, Brennon, Duvick, Lisa, Friedrich, Jillian, Walters, Michael A., Strasser, Jessica, Hawkinson, Jon E., Zoghbi, Huda Y., Henzler, Christine, Orr, Harry T., Lagalwar, Sarita
Published in Neurobiology of disease (01.08.2018)
Published in Neurobiology of disease (01.08.2018)
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Automated Live-Cell Imaging of Synapses in Rat and Human Neuronal Cultures
Green, Matthew V, Pengo, Thomas, Raybuck, Jonathan D, Naqvi, Tahmina, McMullan, Hannah M, Hawkinson, Jon E, Marron Fernandez de Velasco, Ezequiel, Muntean, Brian S, Martemyanov, Kirill A, Satterfield, Rachel, Young, Jr, Samuel M, Thayer, Stanley A
Published in Frontiers in cellular neuroscience (17.10.2019)
Published in Frontiers in cellular neuroscience (17.10.2019)
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The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10
Paulson, Carolyn N, John, Kristen, Baxley, Ryan M, Kurniawan, Fredy, Orellana, Kayo, Francis, Rawle, Sobeck, Alexandra, Eichman, Brandt F, Chazin, Walter J, Aihara, Hideki, Georg, Gunda I, Hawkinson, Jon E, Bielinsky, Anja-Katrin
Published in Open biology (01.08.2019)
Published in Open biology (01.08.2019)
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Human Adenine Nucleotide Translocase (ANT) Modulators Identified by High-Throughput Screening of Transgenic Yeast
Zhang, Yujian, Tian, Defeng, Matsuyama, Hironori, Hamazaki, Takashi, Shiratsuchi, Takayuki, Terada, Naohiro, Hook, Derek J, Walters, Michael A, Georg, Gunda I, Hawkinson, Jon E
Published in Journal of biomolecular screening (01.04.2016)
Published in Journal of biomolecular screening (01.04.2016)
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Design, Synthesis, and in Vitro and in Vivo Evaluation of Ouabain Analogues as Potent and Selective Na,K-ATPase α4 Isoform Inhibitors for Male Contraception
Syeda, Shameem Sultana, Sánchez, Gladis, Hong, Kwon Ho, Hawkinson, Jon E, Georg, Gunda I, Blanco, Gustavo
Published in Journal of medicinal chemistry (08.03.2018)
Published in Journal of medicinal chemistry (08.03.2018)
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From HTS to Phase I: The Institute for Therapeutics Discovery and Development at the University of Minnesota
Dosa, Peter I, Georg, Gunda I, Gurvich, Vadim J, Hawkinson, Jon E, Walters, Michael A, Wong, Henry L
Published in Combinatorial chemistry & high throughput screening (01.03.2014)
Published in Combinatorial chemistry & high throughput screening (01.03.2014)
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Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice
Faber, Erik B., Wang, Nan, John, Kristen, Sun, Luxin, Wong, Henry L., Burban, David, Francis, Rawle, Tian, Defeng, Hong, Kwon H., Yang, An, Wang, Liming, Elsaid, Mazen, Khalid, Hira, Levinson, Nicholas M., Schönbrunn, Ernst, Hawkinson, Jon E., Georg, Gunda I.
Published in Journal of medicinal chemistry (09.02.2023)
Published in Journal of medicinal chemistry (09.02.2023)
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Discovery and Characterization of Multiple Classes of Human CatSper Blockers
Carlson, Erick J., Francis, Rawle, Liu, Yutong, Li, Ping, Lyon, Maximilian, Santi, Celia M., Hook, Derek J., Hawkinson, Jon E., Georg, Gunda I.
Published in ChemMedChem (03.08.2022)
Published in ChemMedChem (03.08.2022)
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FBNTI, a DOR-Selective Antagonist That Allosterically Activates MOR within a MOR–DOR Heteromer
Akgün, Eyup, Lunzer, Mary M, Tian, Defeng, Ansonoff, Michael, Pintar, John, Bruce, Daniel, Hawkinson, Jon E, Wilcox, George L, Portoghese, Philip S
Published in Biochemistry (Easton) (11.05.2021)
Published in Biochemistry (Easton) (11.05.2021)
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7‑Methylation of Chenodeoxycholic Acid Derivatives Yields a Substantial Increase in TGR5 Receptor Potency
Nakhi, Ali, McDermott, Connor M, Stoltz, Kristen L, John, Kristen, Hawkinson, Jon E, Ambrose, Elizabeth A, Khoruts, Alexander, Sadowsky, Michael J, Dosa, Peter I
Published in Journal of medicinal chemistry (25.07.2019)
Published in Journal of medicinal chemistry (25.07.2019)
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Strategies for developing retinoic acid receptor alpha-selective antagonists as novel agents for male contraception
Al Noman, Md Abdullah, Cuellar, Rebecca A.D., Kyzer, Jillian L., Chung, Sanny S.W., Cheryala, Narsihmulu, Holth, Trinh A.D., Maitra, Soma, Naqvi, Tahmina, Wong, Henry L., Schönbrunn, Ernst, Hawkinson, Jon E., Wolgemuth, Debra J., Georg, Gunda I.
Published in European journal of medicinal chemistry (05.12.2023)
Published in European journal of medicinal chemistry (05.12.2023)
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Cooperativity Between Orthosteric Inhibitors and Allosteric Inhibitor 8‑Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-Dependent Kinase 2
Faber, Erik B, Tian, Defeng, Burban, David, Levinson, Nicholas M, Hawkinson, Jon E, Georg, Gunda I
Published in ACS chemical biology (17.07.2020)
Published in ACS chemical biology (17.07.2020)
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Corrigendum: Discovery and Characterization of Multiple Classes of Human CatSper Blockers
Carlson, Erick J., Francis, Rawle, Liu, Yutong, Li, Ping, Lyon, Maximilian, Santi, Celia M., Hook, Derek J., Hawkinson, Jon E., Georg, Gunda I.
Published in ChemMedChem (06.10.2022)
Published in ChemMedChem (06.10.2022)
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Pharmacological, Pharmacokinetic, and Primate Analgesic Efficacy Profile of the Novel Bradykinin B1 Receptor Antagonist ELN441958
Hawkinson, Jon E, Szoke, Balazs G, Garofalo, Albert W, Hom, Dennis S, Zhang, Hongbing, Dreyer, Mark, Fukuda, Juri Y, Chen, Linda, Samant, Bhushan, Simmonds, Stellanie, Zeitz, Karla P, Wadsworth, Angie, Liao, Anna, Chavez, Raymond A, Zmolek, Wes, Ruslim, Lany, Bova, Michael P, Holcomb, Ryan, Butelman, Eduardo R, Ko, Mei-Chuan, Malmberg, Annika B
Published in The Journal of pharmacology and experimental therapeutics (01.08.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2007)
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Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis
Hanna, Carol B, Mudaliar, Deepti, John, Kristen, Allen, C. Leigh, Sun, Luxin, Hawkinson, Jon E, Schönbrunn, Ernst, Georg, Gunda I, Jensen, Jeffrey T
Published in Biology of reproduction (01.08.2020)
Published in Biology of reproduction (01.08.2020)
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Investigation of selective retinoic acid receptor alpha antagonist ER‐50891 and related analogs for male contraception
Kyzer, Jillian L., Noman, Md Abdullah Al, Cuellar, Rebecca A. D., Chung, Sanny S. W., Maitra, Soma, Naqvi, Tahmina, Hawkinson, Jon E., Wolgemuth, Debra J., Georg, Gunda I.
Published in Archiv der Pharmazie (Weinheim) (01.07.2023)
Published in Archiv der Pharmazie (Weinheim) (01.07.2023)
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