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Published in Brain (London, England : 1878) (01.07.2014)
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The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export function
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Published in Nature communications (07.09.2023)
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Proteinopathies as Hallmarks of Impaired Gene Expression, Proteostasis and Mitochondrial Function in Amyotrophic Lateral Sclerosis
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Chtop is a component of the dynamic TREX mRNA export complex
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Published in The EMBO journal (06.02.2013)
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Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features
Shaw, Matthew P, Higginbottom, Adrian, McGown, Alexander, Castelli, Lydia M, James, Evlyn, Hautbergue, Guillaume M, Shaw, Pamela J, Ramesh, Tennore M
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A Simple Method for Improving Protein Solubility and Long-Term Stability
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Published in Journal of the American Chemical Society (28.07.2004)
Published in Journal of the American Chemical Society (28.07.2004)
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A Y374X TDP43 truncation leads to an altered metabolic profile in amyotrophic lateral sclerosis fibroblasts driven by pyruvate and TCA cycle intermediate alterations
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Published in Frontiers in aging neuroscience (11.05.2023)
Published in Frontiers in aging neuroscience (11.05.2023)
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RNA Helicases in Microsatellite Repeat Expansion Disorders and Neurodegeneration
Castelli, Lydia M, Benson, Bridget C, Huang, Wan-Ping, Lin, Ya-Hui, Hautbergue, Guillaume M
Published in Frontiers in genetics (12.05.2022)
Published in Frontiers in genetics (12.05.2022)
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C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten
Stopford, Matthew J, Higginbottom, Adrian, Hautbergue, Guillaume M, Cooper-Knock, Johnathan, Mulcahy, Padraig J, De Vos, Kurt J, Renton, Alan E, Pliner, Hannah, Calvo, Andrea, Chio, Adriano, Traynor, Bryan J, Azzouz, Mimoun, Heath, Paul R, Kirby, Janine, Shaw, Pamela J
Published in Human molecular genetics (15.03.2017)
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Published in PLoS pathogens (01.02.2014)
Published in PLoS pathogens (01.02.2014)
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Published in Molecular neurodegeneration (10.08.2021)
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Translating SOD1 Gene Silencing toward the Clinic: A Highly Efficacious, Off-Target-free, and Biomarker-Supported Strategy for fALS
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Published in Molecular therapy. Nucleic acids (07.09.2018)
Published in Molecular therapy. Nucleic acids (07.09.2018)
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Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation
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Published in Frontiers in cellular neuroscience (16.12.2022)
Published in Frontiers in cellular neuroscience (16.12.2022)
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The Association between Polygenic Hazard and Markers of Alzheimer's Disease Following Stratification for APOE Genotype
De Marco, Matteo, Manca, Riccardo, Kirby, Janine, Hautbergue, Guillaume M, Blackburn, Daniel J, Wharton, Stephen B, Venneri, Annalena, Alzheimer's Disease Neuroimaging Initiative
Published in Current Alzheimer research (01.01.2020)
Published in Current Alzheimer research (01.01.2020)
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