How the Innate Immune System Senses Trouble and Causes Trouble
Hato, Takashi, Dagher, Pierre C
Published in Clinical journal of the American Society of Nephrology (07.08.2015)
Published in Clinical journal of the American Society of Nephrology (07.08.2015)
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Kidney intercalated cells are phagocytic and acidify internalized uropathogenic Escherichia coli
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Published in Nature communications (23.04.2021)
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The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline
Janosevic, Danielle, Myslinski, Jered, McCarthy, Thomas W, Zollman, Amy, Syed, Farooq, Xuei, Xiaoling, Gao, Hongyu, Liu, Yun-Long, Collins, Kimberly S, Cheng, Ying-Hua, Winfree, Seth, El-Achkar, Tarek M, Maier, Bernhard, Melo Ferreira, Ricardo, Eadon, Michael T, Hato, Takashi, Dagher, Pierre C
Published in eLife (15.01.2021)
Published in eLife (15.01.2021)
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Lapachol inhibits glycolysis in cancer cells by targeting pyruvate kinase M2
Shankar Babu, Mani, Mahanta, Sailendra, Lakhter, Alexander J, Hato, Takashi, Paul, Subhankar, Naidu, Samisubbu R
Published in PloS one (02.02.2018)
Published in PloS one (02.02.2018)
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Loss of proximal tubular transcription factor Krüppel-like factor 15 exacerbates kidney injury through loss of fatty acid oxidation
Piret, Sian E., Attallah, Ahmed A., Gu, Xiangchen, Guo, Yiqing, Gujarati, Nehaben A., Henein, Justina, Zollman, Amy, Hato, Takashi, Ma’ayan, Avi, Revelo, Monica P., Dickman, Kathleen G., Chen, Chung-Hsin, Shun, Chia-Tung, Rosenquist, Thomas A., He, John C., Mallipattu, Sandeep K.
Published in Kidney international (01.12.2021)
Published in Kidney international (01.12.2021)
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Two-Photon Intravital Fluorescence Lifetime Imaging of the Kidney Reveals Cell-Type Specific Metabolic Signatures
Hato, Takashi, Winfree, Seth, Day, Richard, Sandoval, Ruben M, Molitoris, Bruce A, Yoder, Mervin C, Wiggins, Roger C, Zheng, Yi, Dunn, Kenneth W, Dagher, Pierre C
Published in Journal of the American Society of Nephrology (01.08.2017)
Published in Journal of the American Society of Nephrology (01.08.2017)
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Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel
LaFavers, Kaice A, Macedo, Etienne, Garimella, Pranav S, Lima, Camila, Khan, Shehnaz, Myslinski, Jered, McClintick, Jeanette, Witzmann, Frank A, Winfree, Seth, Phillips, Carrie L, Hato, Takashi, Dagher, Pierre C, Wu, Xue-Ru, El-Achkar, Tarek M, Micanovic, Radmila
Published in Science translational medicine (02.10.2019)
Published in Science translational medicine (02.10.2019)
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Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney
Micanovic, Radmila, Khan, Shehnaz, Janosevic, Danielle, Lee, Maya E, Hato, Takashi, Srour, Edward F, Winfree, Seth, Ghosh, Joydeep, Tong, Yan, Rice, Susan E, Dagher, Pierre C, Wu, Xue-Ru, El-Achkar, Tarek M
Published in Journal of the American Society of Nephrology (01.03.2018)
Published in Journal of the American Society of Nephrology (01.03.2018)
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The kidney protects against sepsis by producing systemic uromodulin
LaFavers, Kaice A, Hage, Chadi A, Gaur, Varun, Micanovic, Radmila, Hato, Takashi, Khan, Shehnaz, Winfree, Seth, Doshi, Simit, Moorthi, Ranjani N, Twigg, Homer, Wu, Xue-Ru, Dagher, Pierre C, Srour, Edward F, El-Achkar, Tarek M
Published in American journal of physiology. Renal physiology (01.08.2022)
Published in American journal of physiology. Renal physiology (01.08.2022)
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Endotoxin Uptake by S1 Proximal Tubular Segment Causes Oxidative Stress in the Downstream S2 Segment
KALAKECHE, Rabih, HATO, Takashi, RHODES, Georges, DUNN, Kenneth W, EL-ACHKAR, Tarek M, PLOTKIN, Zoya, SANDOVAL, Ruben M, DAGHER, Pierre C
Published in Journal of the American Society of Nephrology (01.08.2011)
Published in Journal of the American Society of Nephrology (01.08.2011)
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Carvedilol suppresses ryanodine receptor-dependent Ca2+ bursts in human neurons bearing PSEN1 variants found in early onset Alzheimer's disease
Hori, Atsushi, Inaba, Haruka, Hato, Takashi, Tanaka, Kimie, Sato, Shoichi, Okamoto, Mizuho, Horiuchi, Yuna, Paran, Faith Jessica, Tabe, Yoko, Mori, Shusuke, Rosales, Corina, Akamatsu, Wado, Murayama, Takashi, Kurebayashi, Nagomi, Sakurai, Takashi, Ai, Tomohiko, Miida, Takashi
Published in PloS one (2024)
Published in PloS one (2024)
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Integration of spatial and single-cell transcriptomics localizes epithelial cell-immune cross-talk in kidney injury
Melo Ferreira, Ricardo, Sabo, Angela R, Winfree, Seth, Collins, Kimberly S, Janosevic, Danielle, Gulbronson, Connor J, Cheng, Ying-Hua, Casbon, Lauren, Barwinska, Daria, Ferkowicz, Michael J, Xuei, Xiaoling, Zhang, Chi, Dunn, Kenneth W, Kelly, Katherine J, Sutton, Timothy A, Hato, Takashi, Dagher, Pierre C, El-Achkar, Tarek M, Eadon, Michael T
Published in JCI insight (22.06.2021)
Published in JCI insight (22.06.2021)
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The macrophage mediates the renoprotective effects of endotoxin preconditioning
Hato, Takashi, Winfree, Seth, Kalakeche, Rabih, Dube, Shataakshi, Kumar, Rakesh, Yoshimoto, Momoko, Plotkin, Zoya, Dagher, Pierre C
Published in Journal of the American Society of Nephrology (01.06.2015)
Published in Journal of the American Society of Nephrology (01.06.2015)
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p53 Is Renoprotective after Ischemic Kidney Injury by Reducing Inflammation
SUTTON, Timothy A, HATO, Takashi, MAI, Erik, YOSHIMOTO, Momoko, KUEHL, Sarah, ANDERSON, Melissa, MANG, Henry, PLOTKIN, Zoya, CHAN, Rebecca J, DAGHER, Pierre C
Published in Journal of the American Society of Nephrology (01.01.2013)
Published in Journal of the American Society of Nephrology (01.01.2013)
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Propranolol treatment during repetitive mild traumatic brain injuries induces transcriptomic changes in the bone marrow of mice
Smith, Jared A, Nguyen, Tyler, Davis, Brittany C, Lahiri, Debomoy K, Hato, Takashi, Obukhov, Alexander G, White, Fletcher A
Published in Frontiers in neuroscience (12.09.2023)
Published in Frontiers in neuroscience (12.09.2023)
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Endotoxin Preconditioning Reprograms S1 Tubules and Macrophages to Protect the Kidney
Hato, Takashi, Zollman, Amy, Plotkin, Zoya, El-Achkar, Tarek M, Maier, Bernhard F, Pay, S Louise, Dube, Shataakshi, Cabral, Pablo, Yoshimoto, Momoko, McClintick, Jeanette, Dagher, Pierre C
Published in Journal of the American Society of Nephrology (01.01.2018)
Published in Journal of the American Society of Nephrology (01.01.2018)
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Th1 cytokine endotype discriminates and predicts severe complications in COVID-19
Hasegawa, Takehiro, Hato, Takashi, Okayama, Toshitsugu, Ikeo, Kazuho, Miyamoto, Yoshiaki, Iwanaga, Niina, Suzuki, Kohjin, Yoshida, Maho, Yamashita, Kazuto, Yamashita, Saya, Tamada, Eiya, Khasawneh, Abdullah, Paran, Faith Jessica, Oyama, Rieko, Naito, Toshio, Noda, Kenta, Tabe, Yoko
Published in European cytokine network (01.06.2022)
Published in European cytokine network (01.06.2022)
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Exogenous Gene Transmission of Isocitrate Dehydrogenase 2 Mimics Ischemic Preconditioning Protection
Kolb, Alexander L, Corridon, Peter R, Zhang, Shijun, Xu, Weimin, Witzmann, Frank A, Collett, Jason A, Rhodes, George J, Winfree, Seth, Bready, Devin, Pfeffenberger, Zechariah J, Pomerantz, Jeremy M, Hato, Takashi, Nagami, Glenn T, Molitoris, Bruce A, Basile, David P, Atkinson, Simon J, Bacallao, Robert L
Published in Journal of the American Society of Nephrology (01.04.2018)
Published in Journal of the American Society of Nephrology (01.04.2018)
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A practical method for monitoring FRET-based biosensors in living animals using two-photon microscopy
Tao, Wen, Rubart, Michael, Ryan, Jennifer, Xiao, Xiao, Qiao, Chunping, Hato, Takashi, Davidson, Michael W, Dunn, Kenneth W, Day, Richard N
Published in American Journal of Physiology: Cell Physiology (01.12.2015)
Published in American Journal of Physiology: Cell Physiology (01.12.2015)
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Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML
Yamatani, Kotoko, Ai, Tomohiko, Saito, Kaori, Suzuki, Koya, Hori, Atsushi, Kinjo, Sonoko, Ikeo, Kazuho, Ruvolo, Vivian, Zhang, Weiguo, Mak, Po Yee, Kaczkowski, Bogumil, Harada, Hironori, Katayama, Kazuhiro, Sugimoto, Yoshikazu, Myslinski, Jered, Hato, Takashi, Miida, Takashi, Konopleva, Marina, Hayashizaki, Yoshihide, Carter, Bing Z., Tabe, Yoko, Andreeff, Michael
Published in Translational oncology (01.04.2022)
Published in Translational oncology (01.04.2022)
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