A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain
Chih, Ben, Liu, Peter, Chinn, Yvonne, Chalouni, Cecile, Komuves, Laszlo G., Hass, Philip E., Sandoval, Wendy, Peterson, Andrew S.
Published in Nature cell biology (01.01.2012)
Published in Nature cell biology (01.01.2012)
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Journal Article
Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates
Shen, Ben-Quan, Xu, Keyang, Liu, Luna, Raab, Helga, Bhakta, Sunil, Kenrick, Margaret, Parsons-Reponte, Kathryn L, Tien, Janet, Yu, Shang-Fan, Mai, Elaine, Li, Dongwei, Tibbitts, Jay, Baudys, Jakub, Saad, Ola M, Scales, Suzie J, McDonald, Paul J, Hass, Philip E, Eigenbrot, Charles, Nguyen, Trung, Solis, Willy A, Fuji, Reina N, Flagella, Kelly M, Patel, Darshana, Spencer, Susan D, Khawli, Leslie A, Ebens, Allen, Wong, Wai Lee, Vandlen, Richard, Kaur, Surinder, Sliwkowski, Mark X, Scheller, Richard H, Polakis, Paul, Junutula, Jagath R
Published in Nature biotechnology (01.02.2012)
Published in Nature biotechnology (01.02.2012)
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Journal Article
Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye
Shatz, Whitney, Hass, Philip E, Peer, Nikhil, Paluch, Maciej T, Blanchette, Craig, Han, Guanghui, Sandoval, Wendy, Morando, Ashley, Loyet, Kelly M, Bantseev, Vladimir, Booler, Helen, Crowell, Susan, Kamath, Amrita, Scheer, Justin M, Kelley, Robert F
Published in PloS one (28.06.2019)
Published in PloS one (28.06.2019)
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Journal Article
Contribution of Antibody Hydrodynamic Size to Vitreal Clearance Revealed through Rabbit Studies Using a Species-Matched Fab
Shatz, Whitney, Hass, Philip E, Mathieu, Mary, Kim, Hok Seon, Leach, Kim, Zhou, Michelle, Crawford, Yongping, Shen, Amy, Wang, Kathryn, Chang, Debby P, Maia, Mauricio, Crowell, Susan R, Dickmann, Leslie, Scheer, Justin M, Kelley, Robert F
Published in Molecular pharmaceutics (06.09.2016)
Published in Molecular pharmaceutics (06.09.2016)
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Journal Article
The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation
Martinez-Martin, Nadia, Ramani, Sree R., Hackney, Jason A., Tom, Irene, Wranik, Bernd J., Chan, Michelle, Wu, Johnny, Paluch, Maciej T., Takeda, Kentaro, Hass, Philip E., Clark, Hilary, Gonzalez, Lino C.
Published in Nature communications (05.05.2016)
Published in Nature communications (05.05.2016)
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Journal Article
Complement inhibition in cynomolgus monkeys by anti-factor d antigen-binding fragment for the treatment of an advanced form of dry age-related macular degeneration
Loyet, Kelly M, Good, Jeremy, Davancaze, Teresa, Sturgeon, Lizette, Wang, Xiangdan, Yang, Jihong, Le, Kha N, Wong, Maureen, Hass, Philip E, van Lookeren Campagne, Menno, Haughney, Peter C, Morimoto, Alyssa, Damico-Beyer, Lisa A, DeForge, Laura E
Published in The Journal of pharmacology and experimental therapeutics (01.12.2014)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2014)
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Journal Article
Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement
Katschke, Kenneth J., Stawicki, Scott, Yin, Jianping, Steffek, Micah, Xi, Hongkang, Sturgeon, Lizette, Hass, Philip E., Loyet, Kelly M., DeForge, Laura, Wu, Yan, van Lookeren Campagne, Menno, Wiesmann, Christian
Published in The Journal of biological chemistry (17.04.2009)
Published in The Journal of biological chemistry (17.04.2009)
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Journal Article
Complement Receptor of the Ig Superfamily Enhances Complement-Mediated Phagocytosis in a Subpopulation of Tissue Resident Macrophages
Gorgani, Nick N, He, Jeannie Q, Katschke, Kenneth J., Jr, Helmy, Karim Y, Xi, Hongkang, Steffek, Micah, Hass, Philip E, van Lookeren Campagne, Menno
Published in The Journal of immunology (1950) (01.12.2008)
Published in The Journal of immunology (1950) (01.12.2008)
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Journal Article
Domain-Specific Antibodies Reveal Differences in the Membrane Topologies of Apolipoprotein L1 in Serum and Podocytes
Gupta, Nidhi, Wang, Xinhua, Wen, Xiaohui, Moran, Paul, Paluch, Maciej, Hass, Philip E, Heidersbach, Amy, Haley, Benjamin, Kirchhofer, Daniel, Brezski, Randall J, Peterson, Andrew S, Scales, Suzie J
Published in Journal of the American Society of Nephrology (01.09.2020)
Published in Journal of the American Society of Nephrology (01.09.2020)
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Journal Article
Genetic analysis reveals that amyloid precursor protein and death receptor 6 function in the same pathway to control axonal pruning independent of β-secretase
Olsen, Olav, Kallop, Dara Y, McLaughlin, Todd, Huntwork-Rodriguez, Sarah, Wu, Zhuhao, Duggan, Cynthia D, Simon, David J, Lu, Yanmei, Easley-Neal, Courtney, Takeda, Kentaro, Hass, Philip E, Jaworski, Alexander, O'Leary, Dennis D M, Weimer, Robby M, Tessier-Lavigne, Marc
Published in The Journal of neuroscience (07.05.2014)
Published in The Journal of neuroscience (07.05.2014)
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Journal Article
Inhibiting Alternative Pathway Complement Activation by Targeting the Factor D Exosite
Katschke, Kenneth J., Wu, Ping, Ganesan, Rajkumar, Kelley, Robert F., Mathieu, Mary A., Hass, Philip E., Murray, Jeremy, Kirchhofer, Daniel, Wiesmann, Christian, van Lookeren Campagne, Menno
Published in The Journal of biological chemistry (13.04.2012)
Published in The Journal of biological chemistry (13.04.2012)
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Journal Article
Structure of C3b in complex with CRIg gives insights into regulation of complement activation
Fairbrother, Wayne J, Katschke, Kenneth J, Yin, JianPing, DeForge, Laura, McCallum, Scott A, Helmy, Karim Y, Wiesmann, Christian, Embuscado, Lizette, Hass, Philip E, van Lookeren Campagne, Menno, Steffek, Micah
Published in Nature (09.11.2006)
Published in Nature (09.11.2006)
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Journal Article
Balancing Efficacy and Safety of an Anti-DLL4 Antibody through Pharmacokinetic Modulation
Couch, Jessica A, Zhang, Gu, Beyer, Joseph C, de Zafra, Christina L Zuch, Gupta, Priyanka, Kamath, Amrita V, Lewin-Koh, Nicholas, Tarrant, Jacqueline, Allamneni, Krishna P, Cain, Gary, Yee, Sharon, Ross, Sarajane, Cook, Ryan, Tsai, Siao Ping, Ruppel, Jane, Ridgway, John Brady, Paluch, Maciej, Hass, Philip E, Franklin, Jayme, Yan, Minhong
Published in Clinical cancer research (15.03.2016)
Published in Clinical cancer research (15.03.2016)
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Journal Article
Evaluation of Fluorophotometry to Assess the Vitreal Pharmacokinetics of Protein Therapeutics
Dickmann, Leslie J, Yip, Victor, Li, Cuiwen, Abundes, Jr, Juan, Maia, Mauricio, Young, Cynthia, Stainton, Shannon, Hass, Philip E, Joseph, Sean B, Prabhu, Saileta, Boswell, C Andrew
Published in Investigative ophthalmology & visual science (01.10.2015)
Published in Investigative ophthalmology & visual science (01.10.2015)
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Journal Article
Impact of SPR biosensor assay configuration on antibody: Neonatal Fc receptor binding data
Wang, Xiangdan, McKay, Patrick, Yee, Liliana T, Dutina, George, Hass, Philip E, Nijem, Ihsan, Allison, David, Cowan, Kyra J, Lin, Kevin, Quarmby, Valerie, Yang, Jihong
Published in mAbs (17.02.2017)
Published in mAbs (17.02.2017)
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Journal Article
In Vivo Stability Profiles of Anti-factor D Molecules Support Long-Acting Delivery Approaches
Loyet, Kelly M, Hass, Philip E, Sandoval, Wendy N, Morando, Ashley, Liu, Peter, Shatz, Whitney, Dickmann, Leslie, Kenrick, Margaret, Good, Jeremy, Davancaze, Teresa, Morimoto, Alyssa M, Kelley, Robert F, Scheer, Justin M
Published in Molecular pharmaceutics (07.01.2019)
Published in Molecular pharmaceutics (07.01.2019)
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Journal Article
Automated high throughput microscale antibody purification workflows for accelerating antibody discovery
Luan, Peng, Lee, Sophia, Arena, Tia A, Paluch, Maciej, Kansopon, Joe, Viajar, Sharon, Begum, Zahira, Chiang, Nancy, Nakamura, Gerald, Hass, Philip E, Wong, Athena W, Lazar, Greg A, Gill, Avinash
Published in mAbs (19.05.2018)
Published in mAbs (19.05.2018)
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Journal Article
PILRα negatively regulates mouse inflammatory arthritis
Sun, Yonglian, Caplazi, Patrick, Zhang, Juan, Mazloom, Anita, Kummerfeld, Sarah, Quinones, Gabriel, Senger, Kate, Lesch, Justin, Peng, Ivan, Sebrell, Andrew, Luk, Wilman, Lu, Yanmei, Lin, Zhonghua, Barck, Kai, Young, Judy, Del Rio, Mariela, Lehar, Sophie, Asghari, Vida, Lin, WeiYu, Mariathasan, Sanjeev, DeVoss, Jason, Misaghi, Shahram, Balazs, Mercedesz, Sai, Tao, Haley, Benjamin, Hass, Philip E, Xu, Min, Ouyang, Wenjun, Martin, Flavius, Lee, Wyne P, Zarrin, Ali A
Published in The Journal of immunology (1950) (15.07.2014)
Published in The Journal of immunology (1950) (15.07.2014)
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Journal Article
Corrigendum: The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation
Martinez-Martin, Nadia, Ramani, Sree R, Hackney, Jason A, Tom, Irene, Wranik, Bernd J, Chan, Michelle, Wu, Johnny, Paluch, Maciej T, Takeda, Kentaro, Hass, Philip E, Clark, Hilary, Gonzalez, Lino C
Published in Nature communications (21.08.2017)
Published in Nature communications (21.08.2017)
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Journal Article
Evolutionarily Conserved Paired Immunoglobulin-like Receptor α (PILRα) Domain Mediates Its Interaction with Diverse Sialylated Ligands
Sun, Yonglian, Senger, Kate, Baginski, Tomasz K., Mazloom, Anita, Chinn, Yvonne, Pantua, Homer, Hamidzadeh, Kajal, Ramani, Sree Ranjani, Luis, Elizabeth, Tom, Irene, Sebrell, Andrew, Quinones, Gabriel, Ma, Yan, Mukhyala, Kiran, Sai, Tao, Ding, Jiabing, Haley, Benjamin, Shadnia, Hooman, Kapadia, Sharookh B., Gonzalez, Lino C., Hass, Philip E., Zarrin, Ali A.
Published in The Journal of biological chemistry (04.05.2012)
Published in The Journal of biological chemistry (04.05.2012)
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Journal Article