alpha.-Hydroxy ketones in high enantiomeric purity from asymmetric dihydroxylation of enol ethers
Hashiyama, Tomiki, Morikawa, Kouhei, Sharpless, K. Barry
Published in Journal of organic chemistry (01.09.1992)
Published in Journal of organic chemistry (01.09.1992)
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Journal Article
Catalytic asymmetric dihydroxylation of tetrasubstituted olefins
Morikawa, Kouhei, Park, Jeonghan, Andersson, Pher G, Hashiyama, Tomiki, Sharpless, K. Barry
Published in Journal of the American Chemical Society (01.09.1993)
Published in Journal of the American Chemical Society (01.09.1993)
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Journal Article
Synthesis of taxoids 4. Novel and versatile methods for preparation of new taxoids by employing cis- or trans-phenyl glycidic acid
Yamaguchi, Tetsuo, Harada, Naoyuki, Ozaki, Kunihiko, Hayashi, Masahito, Arakawa, Hiroaki, Hashiyama, Tomiki
Published in Tetrahedron (01.01.1999)
Published in Tetrahedron (01.01.1999)
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Journal Article
Synthesis and Biological Evaluation of Alkyl, Alkoxy, Alkylthio, or Amino-Substituted 2, 3-Dihydro-1, 5-benzothiazepin-4(5H)-ones
INOUE, Hirozumi, KONDA, Mikihiko, HASHIYAMA, Tomiki, OTSUKA, Hisao, WATANABE, AKishige, GAINO, Mitsunori, TAKAHASHI, Kaoru, DATE, Tadamasa, OKAMURA, Kimio, TAKEDA, Mikio, NARITA, Hiroshi, MURATA, Sakae, ODAWARA, AKio, SASAKI, Haruhiko, NAGAO, Taku
Published in Chemical & pharmaceutical bulletin (01.06.1997)
Published in Chemical & pharmaceutical bulletin (01.06.1997)
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Journal Article
Synthesis and Antitumor Activity of 9-Acyloxyellipticines
HARADA, Naoyuki, OZAKI, Kunihiko, ODA, Kouji, NAKANISHI, Noriyuki, OHASHI, Motoaki, HASHIYAMA, Tomiki, TSUJIHARA, Kenji
Published in Chemical & pharmaceutical bulletin (01.07.1997)
Published in Chemical & pharmaceutical bulletin (01.07.1997)
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Journal Article
Synthesis and Antitumor Activity of Quaternary Salts of 2-(2'-Oxoalkoxy)-9-hydroxyellipticines
HARADA, Naoyuki, KAWAGUCHI, Takayuki, INOUE, Isao, OHASHI, Motoaki, ODA, Kouji, HASHIYAMA, Tomiki, TSUJIHARA, Kenji
Published in Chemical & pharmaceutical bulletin (01.01.1997)
Published in Chemical & pharmaceutical bulletin (01.01.1997)
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Journal Article
Synthesis and Biological Activity of O-Alkyl-3-N-aminoacyloxymethyl-5-fluoro-2'-deoxyuridine Derivatives
HARADA, Naoyuki, HONGU, Mitsuya, KAWAGUCHI, Takayuki, OHOHASHI, Motoaki, ODA, Kouji, HASHIYAMA, Tomiki, TSUJIHARA, Kenji
Published in Chemical & pharmaceutical bulletin (1996)
Published in Chemical & pharmaceutical bulletin (1996)
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Journal Article
A novel synthesis of a key intermediate for diltiazem
Seki, Masahiko, Furutani, Toshiyuki, Imashiro, Ritsuo, Kuroda, Tooru, Yamanaka, Takeshi, Harada, Naoyuki, Arakawa, Hiroaki, Kusama, Mari, Hashiyama, Tomiki
Published in Tetrahedron letters (12.11.2001)
Published in Tetrahedron letters (12.11.2001)
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Journal Article
Antiallergic agents. 2. N-(1H-Tetrazol-5-yl)-6-phenyl-2-pyridinecarboxamides
Honma, Yasushi, Oda, Kuniyuki, Hashiyama, Tomiki, Hanamoto, Kyoji, Nakai, Hideo, Inoue, Hirozumi, Ishida, Akihiko, Takeda, Mikio, Ono, Yasutoshi, Tsuzurahara, Kei
Published in Journal of medicinal chemistry (01.10.1983)
Published in Journal of medicinal chemistry (01.10.1983)
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Journal Article
Structure of TMC-69, a new antitumor antibiotic from Chrysosporium sp TC 1068
Kohno, J, Hirano, N, Sugawara, K, Nishio, M, Hashiyama, T, Nakanishi, N, Komatsubara, S
Published in Tetrahedron (25.02.2001)
Published in Tetrahedron (25.02.2001)
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Journal Article
Efficient and practical synthesis of both enantiomers of 6-silyloxy-3-pyranone derivatives
Sugawara, Kazutoshi, Imanishi, Yasuhiro, Hashiyama, Tomiki
Published in Tetrahedron: asymmetry (17.11.2000)
Published in Tetrahedron: asymmetry (17.11.2000)
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Journal Article
Synthesis of taxoids 5. Synthesis and evaluation of novel water-soluble prodrugs of a 3′-desphenyl-3′-cyclopropyl analogue of docetaxel
Yamaguchi, Tetsuo, Harada, Naoyuki, Ozaki, Kunihiko, Arakawa, Hiroaki, Oda, Kouji, Nakanishi, Noriyuki, Tsujihara, Kenji, Hashiyama, Tomiki
Published in Bioorganic & medicinal chemistry letters (21.06.1999)
Published in Bioorganic & medicinal chemistry letters (21.06.1999)
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Journal Article
Synthesis of halogen-substituted 1,5-benzothiazepine derivatives and their vasodilating and hypotensive activities
Inoue, Hirozumi, Konda, Mikihiko, Hashiyama, Tomiki, Otsuka, Hisao, Takahashi, Kaoru, Gaino, Mitsunori, Date, Tadamasa, Aoe, Keiichi, Takeda, Mikio
Published in Journal of medicinal chemistry (01.02.1991)
Published in Journal of medicinal chemistry (01.02.1991)
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