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Dunn, Warwick B, Broadhurst, David, Begley, Paul, Zelena, Eva, Francis-McIntyre, Sue, Anderson, Nadine, Brown, Marie, Knowles, Joshau D, Halsall, Antony, Haselden, John N, Nicholls, Andrew W, Wilson, Ian D, Kell, Douglas B, Goodacre, Royston
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Use of liquid chromatography/time-of-flight mass spectrometry and multivariate statistical analysis shows promise for the detection of drug metabolites in biological fluids
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Chemometric Models for Toxicity Classification Based on NMR Spectra of Biofluids
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Published in Chemical research in toxicology (01.06.2000)
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A gender-specific discriminator in Sprague–Dawley rat urine: The deployment of a metabolic profiling strategy for biomarker discovery and identification
Hodson, Mark P., Dear, Gordon J., Roberts, Andy D., Haylock, Claire L., Ball, Rachel J., Plumb, Robert S., Stumpf, Chris L., Griffin, Julian L., Haselden, John N.
Published in Analytical biochemistry (15.03.2007)
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A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria
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Published in Science translational medicine (15.07.2015)
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A Functional Analysis of Mouse Models of Cardiac Disease through Metabolic Profiling
Jones, Gareth L A H, Sang, Elizabeth, Goddard, Catharine, Mortishire-Smith, Russell J, Sweatman, Brian C, Haselden, John N, Davies, Kay, Grace, Andrew A, Clarke, Kieran, Griffin, Julian L
Published in The Journal of biological chemistry (04.03.2005)
Published in The Journal of biological chemistry (04.03.2005)
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Molecular phenotyping of a UK population: defining the human serum metabolome
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Published in Metabolomics (01.02.2015)
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4,4-Dimethyl-4-silapentane-1-ammonium trifluoroacetate (DSA), a promising universal internal standard for NMR-based metabolic profiling studies of biofluids, including blood plasma and serum
Alum, Mohammed F, Shaw, Paul A, Sweatman, Brian C, Ubhi, Baljit K, Haselden, John N, Connor, Susan C
Published in Metabolomics (01.06.2008)
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Peak Alignment of Urine NMR Spectra Using Fuzzy Warping
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Published in Chemical research in toxicology (01.08.2001)
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DELANEY, Jane, HODSON, Mark P, WATERFIELD, Catherine J, THAKKAR, Hansa, CONNOR, Susan C, SWEATMAN, Brian C, KENNY, Steve P, MCGILL, Paul J, HOLDER, Julie C, HUTTON, Kathryn A, HASELDEN, John N
Published in Archives of toxicology (01.04.2005)
Published in Archives of toxicology (01.04.2005)
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Development of a multivariate statistical model to predict peroxisome proliferation in the rat, based on urinary 1H-NMR spectral patterns
Connor, Susan C., Hodson, Mark P., Ringeissen, Stephanie, Sweatman, Brian C., Mcgill, Paul J., Waterfield, Catherine J., Haselden, John N.
Published in Biomarkers (01.07.2004)
Published in Biomarkers (01.07.2004)
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Effects of feeding and body weight loss on the 1H-NMR-based urine metabolic profiles of male Wistar Han Rats: Implications for biomarker discovery
Connor, Susan C., Wu, Wen, Sweatman, Brian C., Manini, Jodi, Haselden, John N., Crowther, Daniel J., Waterfield, Catherine J.
Published in Biomarkers (01.03.2004)
Published in Biomarkers (01.03.2004)
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Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification of N -methylnicotinamide and N -methyl-4-pyridone-3-carboxamide by 1H nuclear magnetic resonance and high performance liquid chromatography
Ringeissen, Stephanie, Connor, Susan C., Brown, H. Roger, Sweatman, Brian C., Hodson, Mark P., Kenny, Steve P., Haworth, Richard I., Mcgill, Paul, Price, Mark A., Aylott, Mike C., Nunez, Derek J., Haselden, John N., Waterfield, Catherine J.
Published in Biomarkers (01.05.2003)
Published in Biomarkers (01.05.2003)
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