Conquering rheumatic diseases: are parasitic worms the answer?
Buitrago, Geraldine, Harnett, Margaret M., Harnett, William
Published in Trends in parasitology (01.09.2023)
Published in Trends in parasitology (01.09.2023)
Get full text
Journal Article
The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing
Crowe, Jenny, Lumb, Felicity E, Doonan, James, Broussard, Margaux, Tarafdar, Anuradha, Pineda, Miguel A, Landabaso, Carmen, Mulvey, Lorna, Hoskisson, Paul A, Babayan, Simon A, Selman, Colin, Harnett, William, Harnett, Margaret M
Published in PLoS pathogens (12.03.2020)
Published in PLoS pathogens (12.03.2020)
Get full text
Journal Article
The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis
Doonan, James, Tarafdar, Anuradha, Pineda, Miguel A, Lumb, Felicity E, Crowe, Jenny, Khan, Aneesah M, Hoskisson, Paul A, Harnett, Margaret M, Harnett, William
Published in Nature communications (05.04.2019)
Published in Nature communications (05.04.2019)
Get full text
Journal Article
Suppression of inflammatory arthritis by the parasitic worm product ES-62 is associated with epigenetic changes in synovial fibroblasts
Corbet, Marlene, Pineda, Miguel A, Yang, Kun, Tarafdar, Anuradha, McGrath, Sarah, Nakagawa, Rinako, Lumb, Felicity E, Suckling, Colin J, Harnett, William, Harnett, Margaret M
Published in PLoS pathogens (01.11.2021)
Published in PLoS pathogens (01.11.2021)
Get full text
Journal Article
IL-33/ST2 signalling and crosstalk with FcεRI and TLR4 is targeted by the parasitic worm product, ES-62
Ball, Dimity H, Al-Riyami, Lamyaa, Harnett, William, Harnett, Margaret M
Published in Scientific reports (14.03.2018)
Published in Scientific reports (14.03.2018)
Get full text
Journal Article
Cytohesin-2/ARNO: A Novel Bridge Between Cell Migration and Immunoregulation in Synovial Fibroblasts
Wang, Yilin, Çil, Çağlar, Harnett, Margaret M, Pineda, Miguel A
Published in Frontiers in immunology (12.01.2022)
Published in Frontiers in immunology (12.01.2022)
Get full text
Journal Article
The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17-producing cellular network at multiple sites
Pineda, Miguel A., McGrath, Mairi A., Smith, Pauline C., Al-Riyami, Lamyaa, Rzepecka, Justyna, Gracie, J. Alastair, Harnett, William, Harnett, Margaret M.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2012)
Get full text
Journal Article
Synthetic small molecule analogues of the immunomodulatory Acanthocheilonema viteae product ES-62 promote metabolic homeostasis during obesity in a mouse model
Lumb, Felicity E., Crowe, Jenny, Doonan, James, Suckling, Colin J., Selman, Colin, Harnett, Margaret M., Harnett, William
Published in Molecular and biochemical parasitology (01.12.2019)
Published in Molecular and biochemical parasitology (01.12.2019)
Get full text
Journal Article
ES‐62 Protects Against Collagen‐Induced Arthritis by Resetting Interleukin‐22 Toward Resolution of Inflammation in the Joints
Pineda, Miguel A., Rodgers, David T., Al‐Riyami, Lamyaa, Harnett, William, Harnett, Margaret M.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2014)
Get full text
Journal Article
The parasitic worm product ES-62 protects the osteoimmunology axis in a mouse model of obesity-accelerated ageing
Harnett, Margaret M, Doonan, James, Lumb, Felicity E, Crowe, Jenny, Damink, Roel Olde, Buitrago, Geraldine, Duncombe-Moore, Josephine, Wilkinson, Debbie I, Suckling, Colin J, Selman, Colin, Harnett, William
Published in Frontiers in immunology (29.08.2022)
Published in Frontiers in immunology (29.08.2022)
Get full text
Journal Article
Designing Anti-inflammatory Drugs from Parasitic Worms: A Synthetic Small Molecule Analogue of the Acanthocheilonema viteae Product ES-62 Prevents Development of Collagen-Induced Arthritis
Al-Riyami, Lamyaa, Pineda, Miguel A, Rzepecka, Justyna, Huggan, Judith K, Khalaf, Abedawn I, Suckling, Colin J, Scott, Fraser J, Rodgers, David T, Harnett, Margaret M, Harnett, William
Published in Journal of medicinal chemistry (27.12.2013)
Published in Journal of medicinal chemistry (27.12.2013)
Get full text
Journal Article
The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model
Aprahamian, Tamar R., Zhong, Xuemei, Amir, Shahzada, Binder, Christoph J., Chiang, Lo-Ku, Al-Riyami, Lamyaa, Gharakhanian, Raffi, Harnett, Margaret M., Harnett, William, Rifkin, Ian R.
Published in International journal for parasitology (01.03.2015)
Published in International journal for parasitology (01.03.2015)
Get full text
Journal Article
Protection against lung pathology during obesity-accelerated ageing in mice by the parasitic worm product ES-62
Harnett, Margaret M, Lumb, Felicity E, Crowe, Jenny, Doonan, James, Buitrago, Geraldine, Brown, Stephanie, Thom, Gillian, MacDonald, Amy, Suckling, Colin J, Selman, Colin, Harnett, William
Published in Frontiers in immunology (2023)
Published in Frontiers in immunology (2023)
Get full text
Journal Article