Outcomes after cessation of mepolizumab therapy in severe eosinophilic asthma: A 12-month follow-up analysis
Haldar, Pranabashis, MD, Brightling, Christopher E., PhD, Singapuri, Amisha, BSc, Hargadon, Beverley, BSc, Gupta, Sumit, PhD, Monteiro, William, BSc, Bradding, Peter, PhD, Green, Ruth H., MD, Wardlaw, Andrew J., PhD, Ortega, Hector, PhD, Pavord, Ian D., DM
Published in Journal of allergy and clinical immunology (01.03.2014)
Published in Journal of allergy and clinical immunology (01.03.2014)
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Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma
Haldar, Pranabashis, Brightling, Christopher E, Hargadon, Beverley, Gupta, Sumit, Monteiro, William, Sousa, Ana, Marshall, Richard P, Bradding, Peter, Green, Ruth H, Wardlaw, Andrew J, Pavord, Ian D
Published in The New England journal of medicine (05.03.2009)
Published in The New England journal of medicine (05.03.2009)
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Journal Article
TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma
Choy, David F, Hart, Kevin M, Borthwick, Lee A, Shikotra, Aarti, Nagarkar, Deepti R, Siddiqui, Salman, Jia, Guiquan, Ohri, Chandra M, Doran, Emma, Vannella, Kevin M, Butler, Claire A, Hargadon, Beverley, Sciurba, Joshua C, Gieseck, Richard L, Thompson, Robert W, White, Sandra, Abbas, Alexander R, Jackman, Janet, Wu, Lawren C, Egen, Jackson G, Heaney, Liam G, Ramalingam, Thirumalai R, Arron, Joseph R, Wynn, Thomas A, Bradding, Peter
Published in Science translational medicine (19.08.2015)
Published in Science translational medicine (19.08.2015)
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Journal Article
Lung function decline and variable airway inflammatory pattern: Longitudinal analysis of severe asthma
Newby, Christopher, PhD, Agbetile, Joshua, MRCP, Hargadon, Beverley, RGN, Monteiro, Will, MSc, Green, Ruth, FRCP, MD, Pavord, Ian, FRCP, MD, Brightling, Christopher, FRCP, PhD, Siddiqui, Salman, MRCP, PhD
Published in Journal of allergy and clinical immunology (01.08.2014)
Published in Journal of allergy and clinical immunology (01.08.2014)
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Journal Article
Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma
Shikotra, Aarti, BSc, Choy, David F., BSc, Ohri, Chandra M., MD, Doran, Emma, BSc, Butler, Claire, MBBCh, Hargadon, Beverley, BSc, Shelley, Maria, BA, Abbas, Alexander R., PhD, Austin, Cary D., MD, PhD, Jackman, Janet, MSc, Wu, Lawren C., PhD, Heaney, Liam G., MD, Arron, Joseph R., MD, PhD, Bradding, Peter, DM
Published in Journal of allergy and clinical immunology (01.01.2012)
Published in Journal of allergy and clinical immunology (01.01.2012)
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Journal Article
Effectiveness of voriconazole in the treatment of Aspergillus fumigatus –associated asthma (EVITA3 study)
Agbetile, Joshua, MD, Bourne, Michelle, RGN, Fairs, Abbie, PhD, Hargadon, Beverley, RGN, Desai, Dhananjay, MD, Broad, Clare, Morley, Joseph, BSc, Bradding, Peter, DM, FRCP, Brightling, Christopher E., PhD, FRCP, Green, Ruth H., DM, FRCP, Haldar, Pranabashis, DM, MRCP, Pashley, Catherine H., PhD, Pavord, Ian D., DM, FRCP, Wardlaw, Andrew J., PhD, FRCP
Published in Journal of allergy and clinical immunology (01.07.2014)
Published in Journal of allergy and clinical immunology (01.07.2014)
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Journal Article
A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma
Shikotra, Aarti, Choy, David F, Siddiqui, Salman, Arthur, Greer, Nagarkar, Deepti R, Jia, Guiquan, Wright, Adam K A, Ohri, Chandra M, Doran, Emma, Butler, Claire A, Hargadon, Beverley, Abbas, Alexander R, Jackman, Janet, Wu, Lawren C, Heaney, Liam G, Arron, Joseph R, Bradding, Peter
Published in The Journal of immunology (1950) (15.04.2017)
Published in The Journal of immunology (1950) (15.04.2017)
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Journal Article
Diagnosis of COVID-19 by exhaled breath analysis using gas chromatography-mass spectrometry
Ibrahim, Wadah, Cordell, Rebecca L, Wilde, Michael J, Richardson, Matthew, Carr, Liesl, Sundari Devi Dasi, Ananga, Hargadon, Beverley, Free, Robert C, Monks, Paul S, Brightling, Christopher E, Greening, Neil J, Siddiqui, Salman
Published in ERJ Open Research (01.07.2021)
Published in ERJ Open Research (01.07.2021)
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Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum
Ghebre, Michael A, Pang, Pee Hwee, Desai, Dhananjay, Hargadon, Beverley, Newby, Chris, Woods, Joanne, Rapley, Laura, Cohen, Suzanne E, Herath, Athula, Gaillard, Erol A, May, Richard D, Brightling, Chris E
Published in BMC pulmonary medicine (08.08.2019)
Published in BMC pulmonary medicine (08.08.2019)
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A cross-sectional study of patterns of airway dysfunction, symptoms and morbidity in primary care asthma
Shaw, Dominick, Green, Ruth, Berry, Mike, Mellor, Sarah, Hargadon, Beverley, Shelley, Maria, McKenna, Sue, Thomas, Mike, Pavord, Ian
Published in Primary care respiratory journal (01.09.2012)
Published in Primary care respiratory journal (01.09.2012)
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Journal Article
Lung Computational Models and the Role of the Small Airways in Asthma
Foy, Brody H, Soares, Marcia, Bordas, Rafel, Richardson, Matthew, Bell, Alex, Singapuri, Amisha, Hargadon, Beverley, Brightling, Christopher, Burrowes, Kelly, Kay, David, Owers-Bradley, John, Siddiqui, Salman
Published in American journal of respiratory and critical care medicine (15.10.2019)
Published in American journal of respiratory and critical care medicine (15.10.2019)
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Journal Article
COPD exacerbation severity and frequency is associated with impaired macrophage efferocytosis of eosinophils
Eltboli, Osama, Bafadhel, Mona, Hollins, Fay, Wright, Adam, Hargadon, Beverley, Kulkarni, Neeta, Brightling, Christopher
Published in BMC pulmonary medicine (09.07.2014)
Published in BMC pulmonary medicine (09.07.2014)
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Composite type-2 biomarker strategy versus a symptom-risk-based algorithm to adjust corticosteroid dose in patients with severe asthma: a multicentre, single-blind, parallel group, randomised controlled trial
Heaney, Liam G, Busby, John, Hanratty, Catherine E, Djukanovic, Ratko, Woodcock, Ashley, Walker, Samantha M, Hardman, Timothy C, Arron, Joseph R, Choy, David F, Bradding, Peter, Brightling, Christopher E, Chaudhuri, Rekha, Cowan, Douglas C, Mansur, Adel H, Fowler, Stephen J, Niven, Robert M, Howarth, Peter H, Lordan, James L, Menzies-Gow, Andrew, Harrison, Tim W, Robinson, Douglas S, Holweg, Cecile T J, Matthews, John G, Pavord, Ian D
Published in The lancet respiratory medicine (01.01.2021)
Published in The lancet respiratory medicine (01.01.2021)
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IgE Sensitization to Aspergillus fumigatus Is Associated with Reduced Lung Function in Asthma
FAIRS, Abbie, AGBETILE, Joshua, PAVORD, Ian D, WARDLAW, Andrew J, PASHLEY, Catherine H, HARGADON, Beverley, BOURNE, Michelle, MONTEIRO, William R, BRIGHTLING, Christopher E, BRADDING, Peter, GREEN, Ruth H, MUTALITHAS, Kugathasan, DESAI, Dhananjay
Published in American journal of respiratory and critical care medicine (01.12.2010)
Published in American journal of respiratory and critical care medicine (01.12.2010)
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Journal Article
Body Mass and Fat Mass in Refractory Asthma: An Observational 1 Year Follow-Up Study
Wardlaw, Andrew J., Pavord, Ian D., Brightling, Christopher E., Bafadhel, Mona, Bradding, Peter H., Green, Ruth H., Monteiro, William, Singapuri, Amisha, Terry, Sarah, Hargadon, Beverley
Published in Journal of Allergy (01.01.2010)
Published in Journal of Allergy (01.01.2010)
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Journal Article
Exacerbations of severe asthma in patients treated with mepolizumab
Shrimanker, Rahul, Pavord, Ian D, Yancey, Steve, Heaney, Liam G, Green, Ruth H, Bradding, Peter, Hargadon, Beverley, Brightling, Chris E, Wardlaw, Andrew J, Haldar, Pranabashis
Published in The European respiratory journal (01.12.2018)
Published in The European respiratory journal (01.12.2018)
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Journal Article
Visualization of exhaled breath metabolites reveals distinct diagnostic signatures for acute cardiorespiratory breathlessness
Ibrahim, Wadah, Wilde, Michael J, Cordell, Rebecca L, Richardson, Matthew, Salman, Dahlia, Free, Robert C, Zhao, Bo, Singapuri, Amisha, Hargadon, Beverley, Gaillard, Erol A, Suzuki, Toru, Ng, Leong L, Coats, Tim, Thomas, Paul, Monks, Paul S, Brightling, Christopher E, Greening, Neil J, Siddiqui, Salman, Munton, Rachel, Le Quesne, John, Goodall, Alison H, Pandya, Hitesh C, Reynolds, James C, Clokie, Martha R J, Samani, Nilesh J, Barer, Michael R, Shaw, Jacqueline A
Published in Science translational medicine (16.11.2022)
Published in Science translational medicine (16.11.2022)
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Airway pathological heterogeneity in asthma: Visualization of disease microclusters using topological data analysis
Siddiqui, Salman, Shikotra, Aarti, Richardson, Matthew, Doran, Emma, Choy, David, Bell, Alex, Austin, Cary D., Eastham-Anderson, Jeffrey, Hargadon, Beverley, Arron, Joseph R., Wardlaw, Andrew, Brightling, Christopher E., Heaney, Liam G., Bradding, Peter
Published in Journal of allergy and clinical immunology (01.11.2018)
Published in Journal of allergy and clinical immunology (01.11.2018)
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Journal Article
The effects of inhaled corticosteroids on healthy airways
Marchi, Emanuele, Hinks, Timothy S. C., Richardson, Matthew, Khalfaoui, Latifa, Symon, Fiona A., Rajasekar, Poojitha, Clifford, Rachel, Hargadon, Beverley, Austin, Cary D., MacIsaac, Julia L., Kobor, Michael S., Siddiqui, Salman, Mar, Jordan S., Arron, Joseph R., Choy, David F., Bradding, Peter
Published in Allergy (Copenhagen) (01.07.2024)
Published in Allergy (Copenhagen) (01.07.2024)
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Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker‐high and ‐low severe asthma
Khalfaoui, Latifa, Symon, Fiona A., Couillard, Simon, Hargadon, Beverley, Chaudhuri, Rekha, Bicknell, Steve, Mansur, Adel H., Shrimanker, Rahul, Hinks, Timothy S. C., Pavord, Ian D., Fowler, Stephen J., Brown, Vanessa, McGarvey, Lorcan P., Heaney, Liam G., Austin, Cary D., Howarth, Peter H., Arron, Joseph R., Choy, David F., Bradding, Peter
Published in Allergy (Copenhagen) (01.10.2022)
Published in Allergy (Copenhagen) (01.10.2022)
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