Proof-of-concept clinical trial of etokimab shows a key role for IL-33 in atopic dermatitis pathogenesis
Chen, Yi-Ling, Gutowska-Owsiak, Danuta, Hardman, Clare S, Westmoreland, Melanie, MacKenzie, Teena, Cifuentes, Liliana, Waithe, Dominic, Lloyd-Lavery, Antonia, Marquette, Allison, Londei, Marco, Ogg, Graham
Published in Science translational medicine (23.10.2019)
Published in Science translational medicine (23.10.2019)
Get more information
Journal Article
Innate IL-13–producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity
Barlow, Jillian L., PhD, Bellosi, Agustin, PhD, Hardman, Clare S., BSc, Drynan, Lesley F., MSc, Wong, See Heng, PhD, Cruickshank, James P, McKenzie, Andrew N.J., PhD
Published in Journal of allergy and clinical immunology (01.01.2012)
Published in Journal of allergy and clinical immunology (01.01.2012)
Get full text
Journal Article
IL-33 is more potent than IL-25 in provoking IL-13–producing nuocytes (type 2 innate lymphoid cells) and airway contraction
Barlow, Jillian L., PhD, Peel, Samantha, PhD, Fox, Jane, PhD, Panova, Veera, MRes, Hardman, Clare S., BSc, Camelo, Ana, PhD, Bucks, Christine, PhD, Wu, Xiaoying, MD, Kane, Colleen M., PhD, Neill, Daniel R., PhD, Flynn, Robin J., PhD, Sayers, Ian, PhD, Hall, Ian P., DM, McKenzie, Andrew N.J., PhD
Published in Journal of allergy and clinical immunology (01.10.2013)
Published in Journal of allergy and clinical immunology (01.10.2013)
Get full text
Journal Article
A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue
Rana, Batika M J, Jou, Eric, Barlow, Jillian L, Rodriguez-Rodriguez, Noe, Walker, Jennifer A, Knox, Claire, Jolin, Helen E, Hardman, Clare S, Sivasubramaniam, Meera, Szeto, Aydan, Cohen, E Suzanne, Scott, Ian C, Sleeman, Matthew A, Chidomere, Chiamaka I, Cruz Migoni, Sara, Caamano, Jorge, Jorgensen, Helle F, Carobbio, Stefania, Vidal-Puig, Antonio, McKenzie, Andrew N J
Published in The Journal of experimental medicine (02.09.2019)
Published in The Journal of experimental medicine (02.09.2019)
Get full text
Journal Article
Innate Lymphocyte Mechanisms in Skin Diseases
Chen, Yi-Ling, Hardman, Clare S, Yadava, Koshika, Ogg, Graham
Published in Annual review of immunology (26.04.2020)
Published in Annual review of immunology (26.04.2020)
Get full text
Journal Article
Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection
Jayathilaka, Deshni, Gomes, Laksiri, Jeewandara, Chandima, Jayarathna, Geethal. S. Bandara, Herath, Dhanushka, Perera, Pathum Asela, Fernando, Samitha, Wijewickrama, Ananda, Hardman, Clare S., Ogg, Graham S., Malavige, Gathsaurie Neelika
Published in Nature communications (07.12.2018)
Published in Nature communications (07.12.2018)
Get full text
Journal Article
Quantification of dengue virus specific T cell responses and correlation with viral load and clinical disease severity in acute dengue infection
Wijeratne, Dulharie T, Fernando, Samitha, Gomes, Laksiri, Jeewandara, Chandima, Ginneliya, Anushka, Samarasekara, Supun, Wijewickrama, Ananda, Hardman, Clare S, Ogg, Graham S, Malavige, Gathsaurie Neelika
Published in PLoS neglected tropical diseases (01.10.2018)
Published in PLoS neglected tropical diseases (01.10.2018)
Get full text
Journal Article
Transcription factor RORα is critical for nuocyte development
Wong, See Heng, Walker, Jennifer A, Jolin, Helen E, Drynan, Lesley F, Hams, Emily, Camelo, Ana, Barlow, Jillian L, Neill, Daniel R, Panova, Veera, Koch, Ute, Radtke, Freddy, Hardman, Clare S, Hwang, You Yi, Fallon, Padraic G, McKenzie, Andrew N J
Published in Nature immunology (01.03.2012)
Published in Nature immunology (01.03.2012)
Get full text
Journal Article
Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation
Chen, Yi-Ling, Gomes, Tomas, Hardman, Clare S, Vieira Braga, Felipe A, Gutowska-Owsiak, Danuta, Salimi, Maryam, Gray, Nicki, Duncan, David A, Reynolds, Gary, Johnson, David, Salio, Mariolina, Cerundolo, Vincenzo, Barlow, Jillian L, McKenzie, Andrew N J, Teichmann, Sarah A, Haniffa, Muzlifah, Ogg, Graham
Published in The Journal of experimental medicine (02.03.2020)
Published in The Journal of experimental medicine (02.03.2020)
Get full text
Journal Article
CD1a promotes systemic manifestations of skin inflammation
Hardman, Clare S., Chen, Yi-Ling, Wegrecki, Marcin, Ng, Soo Weei, Murren, Robert, Mangat, Davinderpreet, Silva, John-Paul, Munro, Rebecca, Chan, Win Yan, O’Dowd, Victoria, Doyle, Carl, Mori, Prashant, Popplewell, Andy, Rossjohn, Jamie, Lightwood, Daniel, Ogg, Graham S.
Published in Nature communications (07.12.2022)
Published in Nature communications (07.12.2022)
Get full text
Journal Article
Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype
Fraser, Emily, Denney, Laura, Antanaviciute, Agne, Blirando, Karl, Vuppusetty, Chaitanya, Zheng, Yuejuan, Repapi, Emmanouela, Iotchkova, Valentina, Taylor, Stephen, Ashley, Neil, St Noble, Victoria, Benamore, Rachel, Hoyles, Rachel, Clelland, Colin, Rastrick, Joseph M D, Hardman, Clare S, Alham, Nasullah K, Rigby, Rachel E, Simmons, Alison, Rehwinkel, Jan, Ho, Ling-Pei
Published in Frontiers in immunology (05.03.2021)
Published in Frontiers in immunology (05.03.2021)
Get full text
Journal Article
Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production
Salimi, Maryam, Xue, Luzheng, Jolin, Helen, Hardman, Clare, Cousins, David J, McKenzie, Andrew N J, Ogg, Graham S
Published in The Journal of immunology (1950) (01.01.2016)
Published in The Journal of immunology (1950) (01.01.2016)
Get full text
Journal Article
CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms
Huang, Shouxiong, Shahine, Adam, Cheng, Tan-Yun, Chen, Yi-Ling, Ng, Soo Weei, Balaji, Gautham R., Farquhar, Rachel, Gras, Stephanie, Hardman, Clare S., Altman, John D., Tahiri, Nabil, Minnaard, Adriaan J., Ogg, Graham S., Mayfield, Jacob A., Rossjohn, Jamie, Moody, D. Branch
Published in Cell (12.10.2023)
Published in Cell (12.10.2023)
Get full text
Journal Article
Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase
Jarrett, Rachael, Salio, Mariolina, Lloyd-Lavery, Antonia, Subramaniam, Sumithra, Bourgeois, Elvire, Archer, Charles, Cheung, Ka Lun, Hardman, Clare, Chandler, David, Salimi, Maryam, Gutowska-Owsiak, Danuta, de la Serna, Jorge Bernardino, Fallon, Padraic G, Jolin, Helen, Mckenzie, Andrew, Dziembowski, Andrzej, Podobas, Ewa Izabela, Bal, Wojciech, Johnson, David, Moody, D Branch, Cerundolo, Vincenzo, Ogg, Graham
Published in Science translational medicine (10.02.2016)
Published in Science translational medicine (10.02.2016)
Get more information
Journal Article
Dengue virus co-opts innate type 2 pathways to escape early control of viral replication
Fonseka, Chathuranga L., Hardman, Clare S., Woo, Jeongmin, Singh, Randeep, Nahler, Janina, Yang, Jiahe, Chen, Yi-Ling, Kamaladasa, Achala, Silva, Tehani, Salimi, Maryam, Gray, Nicki, Dong, Tao, Malavige, Gathsaurie N., Ogg, Graham S.
Published in Communications biology (22.07.2022)
Published in Communications biology (22.07.2022)
Get full text
Journal Article
CD1a presentation of endogenous antigens by group 2 innate lymphoid cells
Hardman, Clare S, Chen, Yi-Ling, Salimi, Maryam, Jarrett, Rachael, Johnson, David, Järvinen, Valtteri J, Owens, Raymond J, Repapi, Emmanouela, Cousins, David J, Barlow, Jillian L, McKenzie, Andrew N J, Ogg, Graham
Published in Science immunology (22.12.2017)
Published in Science immunology (22.12.2017)
Get more information
Journal Article
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation
Chen, Yi-Ling, Ng, Jessica Soo Weei, Ottakandathil Babu, Rosana, Woo, Jeongmin, Nahler, Janina, Hardman, Clare S, Kurupati, Prathiba, Nussbaum, Lea, Gao, Fei, Dong, Tao, Ladell, Kristin, Price, David A, Duncan, David A, Johnson, David, Gileadi, Uzi, Koohy, Hashem, Ogg, Graham S
Published in Science immunology (08.06.2023)
Published in Science immunology (08.06.2023)
Get more information
Journal Article
IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent
Hardman, Clare S, Chen, Yi-Ling, Salimi, Maryam, Nahler, Janina, Corridoni, Daniele, Jagielowicz, Marta, Fonseka, Chathuranga L, Johnson, David, Repapi, Emmanouela, Cousins, David J, Barlow, Jillian L, McKenzie, Andrew N J, Simmons, Alison, Ogg, Graham
Published in Science immunology (21.05.2021)
Published in Science immunology (21.05.2021)
Get more information
Journal Article