Preparation of (R)-Amines from Racemic Amines with an (S)-Amine Transaminase from Bacillus megaterium
Hanson, Ronald L., Davis, Brian L., Chen, Yijun, Goldberg, Steven L., Parker, William L., Tully, Thomas P., Montana, Michael A., Patel, Ramesh N.
Published in Advanced synthesis & catalysis (09.06.2008)
Published in Advanced synthesis & catalysis (09.06.2008)
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Preparation of an Amino Acid Intermediate for the Dipeptidyl Peptidase IV Inhibitor, Saxagliptin, using a Modified Phenylalanine Dehydrogenase
Hanson, Ronald L., Goldberg, Steven L., Brzozowski, David B., Tully, Thomas P., Cazzulino, Dana, Parker, William L., Lyngberg, Olav K., Vu, Truc C., Wong, Michael K., Patel, Ramesh N.
Published in Advanced synthesis & catalysis (04.06.2007)
Published in Advanced synthesis & catalysis (04.06.2007)
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Discovering Drugs through Biological Transformation: Role of Pharmacologically Active Metabolites in Drug Discovery
Fura, Aberra, Shu, Yue-Zhong, Zhu, Mingshe, Hanson, Ronald L, Roongta, Vikram, Humphreys, W. Griffith
Published in Journal of medicinal chemistry (26.08.2004)
Published in Journal of medicinal chemistry (26.08.2004)
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A Scalable Synthesis of (R,R)‑2,6-Dimethyldihydro‑2H‑pyran-4(3H)‑one
Young, Ian S, Haley, Matthew W, Tam, Annie, Tymonko, Steven A, Xu, Zhongmin, Hanson, Ronald L, Goswami, Animesh
Published in Organic process research & development (16.10.2015)
Published in Organic process research & development (16.10.2015)
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Journal Article
Efficient and Scalable Enantioselective Synthesis of a CGRP Antagonist
Leahy, David K, Fan, Yu, Desai, Lopa V, Chan, Collin, Zhu, Jason, Luo, Guanglin, Chen, Ling, Hanson, Ronald L, Sugiyama, Masano, Rosner, Thorsten, Cuniere, Nicolas, Guo, Zhiwei, Hsiao, Yi, Gao, Qi
Published in Organic letters (21.09.2012)
Published in Organic letters (21.09.2012)
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Discovery of Clinical Candidate 2‑((2S,6S)‑2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3′-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor
Ye, Xiang-Yang, Chen, Stephanie Y, Wu, Shung, Yoon, David S, Wang, Haixia, Hong, Zhenqiu, O’Connor, Stephen P, Li, Jun, Li, James J, Kennedy, Lawrence J, Walker, Steven J, Nayeem, Akbar, Sheriff, Steven, Camac, Daniel M, Ramamurthy, Vidyhashankar, Morin, Paul E, Zebo, Rachel, Taylor, Joseph R, Morgan, Nathan N, Ponticiello, Randolph P, Harrity, Thomas, Apedo, Atsu, Golla, Rajasree, Seethala, Ramakrishna, Wang, Mengmeng, Harper, Timothy W, Sleczka, Bogdan G, He, Bin, Kirby, Mark, Leahy, David K, Li, Jianqing, Hanson, Ronald L, Guo, Zhiwei, Li, Yi-Xin, DiMarco, John D, Scaringe, Raymond, Maxwell, Brad, Moulin, Frederick, Barrish, Joel C, Gordon, David A, Robl, Jeffrey A
Published in Journal of medicinal chemistry (22.06.2017)
Published in Journal of medicinal chemistry (22.06.2017)
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Biotechnology Based Process for Production of a Disulfide-Bridged Peptide
Goswami, Animesh, Goldberg, Steven L, Hanson, Ronald L, Johnston, Robert M, Lyngberg, Olav K, Chan, Yeung, Lo, Ehrlic, Chan, Steven H, de Mas, Nuria, Ramirez, Antonio, Doyle, Richard, Ding, Wei, Gao, Mian, Krystek, Stanley R, Wan, Changhong, Kim, Yeoun jin, Calambur, Deepa, Witmer, Mark, Bryson, James W
Published in Bioconjugate chemistry (18.05.2016)
Published in Bioconjugate chemistry (18.05.2016)
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Journal Article
Enzymatic Reduction of Adamantanones to Chiral Adamantanol Intermediates for the Synthesis of 11-β-Hydroxysteroid Dehydrogenase Inhibitors
Hanson, Ronald L, Goldberg, Steven L, Guo, Zhiwei, Tully, Thomas P, Goswami, Animesh, Ye, Xiang-Yang, Robl, Jeffrey A, Patel, Ramesh N
Published in Organic process research & development (15.08.2014)
Published in Organic process research & development (15.08.2014)
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Journal Article
Enzymatic Preparation of an (S)-Amino Acid from a Racemic Amino Acid
Chen, Yijun, Goldberg, Steven L, Hanson, Ronald L, Parker, William L, Gill, Iqbal, Tully, Thomas P, Montana, Michael A, Goswami, Animesh, Patel, Ramesh N
Published in Organic process research & development (21.01.2011)
Published in Organic process research & development (21.01.2011)
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Journal Article
Selection of an Enantioselective Process for the Preparation of a CGRP Receptor Inhibitor
Cann, Reginald O, Chen, Chung-Pin H, Gao, Qi, Hanson, Ronald L, Hsieh, Daniel, Li, Jun, Lin, Dong, Parsons, Rodney L, Pendri, Yadagiri, Nielsen, R. Brent, Nugent, William A, Parker, William L, Quinlan, Sandra, Reising, Nathan P, Remy, Brenda, Sausker, Justin, Wang, Xuebao
Published in Organic process research & development (21.12.2012)
Published in Organic process research & development (21.12.2012)
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Journal Article
Enzymatic Preparation of a d-Amino Acid from a Racemic Amino Acid or Keto Acid
Hanson, Ronald L, Davis, Brian L, Goldberg, Steven L, Johnston, Robert M, Parker, William L, Tully, Thomas P, Montana, Michael A, Patel, Ramesh N
Published in Organic process research & development (21.11.2008)
Published in Organic process research & development (21.11.2008)
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Journal Article
Enzymatic C-4 deacetylation of 10-deacetylbaccatin III
Hanson, Ronald L, Parker, William L, Patel, Ramesh N
Published in Biotechnology and applied biochemistry (01.09.2006)
Published in Biotechnology and applied biochemistry (01.09.2006)
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Journal Article
Synthesis and activity of a C-8 keto pleuromutilin derivative
Springer, Dane M, Sorenson, Margaret E, Huang, Stella, Connolly, Timothy P, Bronson, Joanne J, Matson, James A, Hanson, Ronald L, Brzozowski, David B, LaPorte, Thomas L, Patel, Ramesh N
Published in Bioorganic & medicinal chemistry letters (19.05.2003)
Published in Bioorganic & medicinal chemistry letters (19.05.2003)
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Journal Article
Synthesis of allysine ethylene acetal using phenylalanine dehydrogenase from Thermoactinomyces intermedius
Hanson, Ronald L, Howell, Jeffrey M, LaPorte, Thomas L, Donovan, Mary Jo, Cazzulino, Dana L, Zannella, Valerie, Montana, Michael A, Nanduri, Venkata B, Schwarz, Steven R, Eiring, Ronald F, Durand, Susan C, Wasylyk, John M, Parker, William L, Liu, Mark S, Okuniewicz, Francis J, Chen, Bang-Chi, Harris, John C, Natalie, Kenneth J, Ramig, Keith, Swaminathan, Shankar, Rosso, Victor W, Pack, Shawn K, Lotz, Bruce T, Bernot, Peter J, Rusowicz, Andrew, Lust, David A, Tse, Kai S, Venit, John J, Szarka, Laszlo J, Patel, Ramesh N
Published in Enzyme and microbial technology (01.03.2000)
Published in Enzyme and microbial technology (01.03.2000)
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Journal Article
Carbon-14 labeling of Saxagliptin (BMS-477118)
Cao, Kai, Bonacorsi Jr, Samuel J., Balasubramanian, Balu, Hanson, Ronald L., Manchand, Percy, Godfrey Jr, Jollie D., Fox, Rita, Christopher, Lisa J., Su, Hong, Iyer, Ramaswamy
Published in Journal of labelled compounds & radiopharmaceuticals (01.11.2007)
Published in Journal of labelled compounds & radiopharmaceuticals (01.11.2007)
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