Production of hepatocyte-like cells from human pluripotent stem cells
Hannan, Nicholas R F, Segeritz, Charis-Patricia, Touboul, Thomas, Vallier, Ludovic
Published in Nature protocols (01.02.2013)
Published in Nature protocols (01.02.2013)
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Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture
Gieseck, 3rd, Richard L, Hannan, Nicholas R F, Bort, Roque, Hanley, Neil A, Drake, Rosemary A L, Cameron, Grant W W, Wynn, Thomas A, Vallier, Ludovic
Published in PloS one (22.01.2014)
Published in PloS one (22.01.2014)
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Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development
Touboul, Thomas, Hannan, Nicholas R. F., Corbineau, Sébastien, Martinez, Amélie, Martinet, Clémence, Branchereau, Sophie, Mainot, Sylvie, Strick‐Marchand, Hélène, Pedersen, Roger, Di Santo, James, Weber, Anne, Vallier, Ludovic
Published in Hepatology (Baltimore, Md.) (01.05.2010)
Published in Hepatology (Baltimore, Md.) (01.05.2010)
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Transplantation of Expanded Fetal Intestinal Progenitors Contributes to Colon Regeneration after Injury
Fordham, Robert P., Yui, Shiro, Hannan, Nicholas R.F., Soendergaard, Christoffer, Madgwick, Alison, Schweiger, Pawel J., Nielsen, Ole H., Vallier, Ludovic, Pedersen, Roger A., Nakamura, Tetsuya, Watanabe, Mamoru, Jensen, Kim B.
Published in Cell stem cell (05.12.2013)
Published in Cell stem cell (05.12.2013)
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Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation
Sampaziotis, Fotios, Cardoso de Brito, Miguel, Madrigal, Pedro, Bertero, Alessandro, Saeb-Parsy, Kourosh, Soares, Filipa A C, Schrumpf, Elisabeth, Melum, Espen, Karlsen, Tom H, Bradley, J Andrew, Gelson, William T H, Davies, Susan, Baker, Alastair, Kaser, Arthur, Alexander, Graeme J, Hannan, Nicholas R F, Vallier, Ludovic
Published in Nature biotechnology (01.08.2015)
Published in Nature biotechnology (01.08.2015)
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Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
Sampaziotis, Fotios, de Brito, Miguel Cardoso, Geti, Imbisaat, Bertero, Alessandro, Hannan, Nicholas RF, Vallier, Ludovic
Published in Nature protocols (01.04.2017)
Published in Nature protocols (01.04.2017)
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Journal Article
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
Yusa, Kosuke, Rashid, S. Tamir, Strick-Marchand, Helene, Varela, Ignacio, Liu, Pei-Qi, Paschon, David E., Miranda, Elena, Ordóñez, Adriana, Hannan, Nicholas R. F., Rouhani, Foad J., Darche, Sylvie, Alexander, Graeme, Marciniak, Stefan J., Fusaki, Noemi, Hasegawa, Mamoru, Holmes, Michael C., Di Santo, James P., Lomas, David A., Bradley, Allan, Vallier, Ludovic
Published in Nature (London) (20.10.2011)
Published in Nature (London) (20.10.2011)
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Regional Differences in Human Biliary Tissues and Corresponding In Vitro–Derived Organoids
Rimland, Casey A., Tilson, Samantha G., Morell, Carola M., Tomaz, Rute A., Lu, Wei‐Yu, Adams, Simone E., Georgakopoulos, Nikitas, Otaizo‐Carrasquero, Francisco, Myers, Timothy G., Ferdinand, John R., Gieseck, Richard L., Sampaziotis, Fotios, Tysoe, Olivia C., Ross, Alexander, Kraiczy, Judith M., Wesley, Brandon, Muraro, Daniele, Zilbauer, Matthias, Oniscu, Gabriel C., Hannan, Nicholas R.F., Forbes, Stuart J., Saeb‐Parsy, Kourosh, Wynn, Thomas A., Vallier, Ludovic
Published in Hepatology (Baltimore, Md.) (01.01.2021)
Published in Hepatology (Baltimore, Md.) (01.01.2021)
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Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs
Bertero, Alessandro, Pawlowski, Matthias, Ortmann, Daniel, Snijders, Kirsten, Yiangou, Loukia, Cardoso de Brito, Miguel, Brown, Stephanie, Bernard, William G, Cooper, James D, Giacomelli, Elisa, Gambardella, Laure, Hannan, Nicholas R F, Iyer, Dharini, Sampaziotis, Fotios, Serrano, Felipe, Zonneveld, Mariëlle C F, Sinha, Sanjay, Kotter, Mark, Vallier, Ludovic
Published in Development (Cambridge) (01.12.2016)
Published in Development (Cambridge) (01.12.2016)
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A Cell-Based Optimised Approach for Rapid and Efficient Gene Editing of Human Pluripotent Stem Cells
Cuevas-Ocaña, Sara, Yang, Jin Ye, Aushev, Magomet, Schlossmacher, George, Bear, Christine E, Hannan, Nicholas R F, Perkins, Neil D, Rossant, Janet, Wong, Amy P, Gray, Michael A
Published in International journal of molecular sciences (01.06.2023)
Published in International journal of molecular sciences (01.06.2023)
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Journal Article
In Vitro and in Vivo Assays for Testing Retinoids Effect on Intestinal Progenitors' Lineage Commitments
Gajera, Krishna R, Fair, Kathryn L, Moran, Gordon W, Hannan, Nicholas R F, Huelsken, Joerg, Ordóñez-Morán, Paloma
Published in Methods in molecular biology (Clifton, N.J.) (2023)
Published in Methods in molecular biology (Clifton, N.J.) (2023)
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hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency
Segeritz, Charis-Patricia, Rashid, Sheikh Tamir, de Brito, Miguel Cardoso, Serra, Maria Paola, Ordonez, Adriana, Morell, Carola Maria, Kaserman, Joseph E., Madrigal, Pedro, Hannan, Nicholas R.F., Gatto, Laurent, Tan, Lu, Wilson, Andrew A., Lilley, Kathryn, Marciniak, Stefan J., Gooptu, Bibek, Lomas, David A., Vallier, Ludovic
Published in Journal of hepatology (01.10.2018)
Published in Journal of hepatology (01.10.2018)
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Journal Article
Generation of Multipotent Foregut Stem Cells from Human Pluripotent Stem Cells
Hannan, Nicholas R.F., Fordham, Robert P., Syed, Yasir A., Moignard, Victoria, Berry, Andrew, Bautista, Ruben, Hanley, Neil A., Jensen, Kim B., Vallier, Ludovic
Published in Stem cell reports (15.10.2013)
Published in Stem cell reports (15.10.2013)
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Journal Article
Generation of hiPSC-Derived Intestinal Organoids for Developmental and Disease Modelling Applications
Durczak, Paulina M, Fair, Kathryn L, Jinks, Nicholas, Cuevas Ocaña, Sara, Sainz Zuñiga, Carlos B, Hannan, Nicholas R F
Published in Journal of visualized experiments (08.03.2024)
Published in Journal of visualized experiments (08.03.2024)
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Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways
Vallier, Ludovic, Touboul, Thomas, Chng, Zhenzhi, Brimpari, Minodora, Hannan, Nicholas, Millan, Enrique, Smithers, Lucy E, Trotter, Matthew, Rugg-Gunn, Peter, Weber, Anne, Pedersen, Roger A
Published in PloS one (30.06.2009)
Published in PloS one (30.06.2009)
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Journal Article
Activin/Nodal Signaling Controls Divergent Transcriptional Networks in Human Embryonic Stem Cells and in Endoderm Progenitors
Brown, Stephanie, Teo, Adrian, Pauklin, Siim, Hannan, Nicholas, Cho, Candy H.‐H., Lim, Bing, Vardy, Leah, Dunn, N. Ray, Trotter, Matthew, Pedersen, Roger, Vallier, Ludovic
Published in Stem cells (Dayton, Ohio) (01.08.2011)
Published in Stem cells (Dayton, Ohio) (01.08.2011)
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Dynamics of 5-carboxylcytosine during hepatic differentiation: Potential general role for active demethylation by DNA repair in lineage specification
Lewis, Lara C., Lo, Peggy Cho Kiu, Foster, Jeremy M., Dai, Nan, Corrêa, Ivan R., Durczak, Paulina M., Duncan, Gary, Ramsawhook, Ashley, Aithal, Guruprasad Padur, Denning, Chris, Hannan, Nicholas R. F., Ruzov, Alexey
Published in Epigenetics (03.04.2017)
Published in Epigenetics (03.04.2017)
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Identification and characterisation of a rare MTTP variant underlying hereditary non-alcoholic fatty liver disease
Grove, Jane I., Lo, Peggy C.K., Shrine, Nick, Barwell, Julian, Wain, Louise V., Tobin, Martin D., Salter, Andrew M., Borkar, Aditi N., Cuevas-Ocaña, Sara, Bennett, Neil, John, Catherine, Ntalla, Ioanna, Jones, Gabriela E., Neal, Christopher P., Thomas, Mervyn G., Kuht, Helen, Gupta, Pankaj, Vemala, Vishwaraj M., Grant, Allister, Adewoye, Adeolu B., Shenoy, Kotacherry T., Balakumaran, Leena K., Hollox, Edward J., Hannan, Nicholas R.F., Aithal, Guruprasad P.
Published in JHEP reports (01.08.2023)
Published in JHEP reports (01.08.2023)
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