Changes in Human Immunodeficiency Virus Type 1 Gag at Positions L449 and P453 Are Linked to I50V Protease Mutants In Vivo and Cause Reduction of Sensitivity to Amprenavir and Improved Viral Fitness In Vitro
Maguire, Michael F, Guinea, Rosario, Griffin, Philip, Macmanus, Sarah, Elston, Robert C, Wolfram, Josie, Richards, Naomi, Hanlon, Mary H, Porter, David J T, Wrin, Terri, Parkin, Neil, Tisdale, Margaret, Furfine, Eric, Petropoulos, Chris, Snowden, B Wendy, Kleim, Jörg-Peter
Published in Journal of Virology (01.08.2002)
Published in Journal of Virology (01.08.2002)
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Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Proteases by GW0385 and Other Arylsulfonamides
Hanlon, Mary H, Porter, David J. T, Furfine, Eric S, Spaltenstein, Andrew, Carter, H. Luke, Danger, Dana, Shu, Arthur Y. L, Kaldor, Istvan W, Miller, John F, Samano, Vicente A
Published in Biochemistry (Easton) (16.11.2004)
Published in Biochemistry (Easton) (16.11.2004)
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Effectors of HIV-1 Protease Peptidolytic Activity
Porter, David J. T, Hanlon, Mary H, Carter, Luke H, Danger, Dana P, Furfine, Eric S
Published in Biochemistry (Easton) (18.09.2001)
Published in Biochemistry (Easton) (18.09.2001)
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Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP)
Haffner, Curt D., Diaz, Caroline J., Miller, Aaron B., Reid, Robert A., Madauss, Kevin P., Hassell, Annie, Hanlon, Mary H., Porter, David J.T., Becherer, J. David, Carter, Luke H.
Published in Bioorganic & medicinal chemistry (01.08.2008)
Published in Bioorganic & medicinal chemistry (01.08.2008)
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Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: The discovery of GW0385
Miller, John F., Andrews, C. Webster, Brieger, Michael, Furfine, Eric S., Hale, Michael R., Hanlon, Mary H., Hazen, Richard J., Kaldor, Istvan, McLean, Ed W., Reynolds, David, Sammond, Douglas M., Spaltenstein, Andrew, Tung, Roger, Turner, Elizabeth M., Xu, Robert X., Sherrill, Ronald G.
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
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Novel arylsulfonamides possessing sub-picomolar HIV protease activities and potent anti-HIV activity against wild-type and drug-resistant viral strains
MILLER, John F, FURFINE, Eric S, HANLON, Mary H, HAZEN, Richard J, RAY, John A, ROBINSON, Laurence, SAMANO, Vicente, SPALTENSTEIN, Andrew
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
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Product Release Is the Major Contributor tok cat for the Hepatitis C Virus Helicase-catalyzed Strand Separation of Short Duplex DNA
Porter, David J.T., Short, Steven A., Hanlon, Mary H., Preugschat, Frank, Wilson, Jeanne E., Willard, Derril H., Consler, Thomas G.
Published in The Journal of biological chemistry (24.07.1998)
Published in The Journal of biological chemistry (24.07.1998)
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Synthesis and biological activity of an acyclic analog of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)propyl]amino]benzoyl]-L-glutamic acid
Kelley, James L, McLean, Ed W, Cohn, Naomi K, Edelstein, Mark P, Duch, David S, Smith, Gary K, Hanlon, Mary H, Ferone, Robert
Published in Journal of medicinal chemistry (01.02.1990)
Published in Journal of medicinal chemistry (01.02.1990)
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Synthesis and biological activity of an acyclic analog of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)propyl]amino]benzoyl]-L-glutamic acid [Erratum to document cited in CA112(7):56616d]
Kelley, James L, McLean, Ed W, Cohn, Naomi K, Edelstein, Mark P, Duch, David S, Smith, Gary K, Hanlon, Mary H, Ferone, Robert
Published in Journal of medicinal chemistry (01.11.1990)
Published in Journal of medicinal chemistry (01.11.1990)
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The E1 Helicase of Human Papillomavirus Type 11 Binds to the Origin of Replication with Low Sequence Specificity
Dixon, Eric P., Pahel, Greg L., Rocque, Warren J., Barnes, Julie A., Lobe, David C., Hanlon, Mary H., Alexander, Kenneth A., Chao, Shih-Fong, Lindley, Kathy, Phelps, William C.
Published in Virology (New York, N.Y.) (10.05.2000)
Published in Virology (New York, N.Y.) (10.05.2000)
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In vivo and in vitro metabolism of 5-deazaacyclotetrahydrofolate, an acyclic tetrahydrofolate analogue
Hanlon, M H, Ferone, R, Mullin, R J, Keith, B R
Published in Cancer research (Chicago, Ill.) (01.06.1990)
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Published in Cancer research (Chicago, Ill.) (01.06.1990)
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Studies on the mechanism of antitumor action of 2-desamino-2-methyl-5,8-dideazaisofolic acid
Hagan, R L, Duch, D S, Smith, G K, Hanlon, M H, Shane, B, Freisheim, J H, Hynes, J B
Published in Biochemical pharmacology (01.03.1991)
Published in Biochemical pharmacology (01.03.1991)
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Novel Arylsulfonamides Possessing Sub-Picomolar HIV Protease Activities and Potent anti-HIV Activity against Wild-Type and Drug-Resistant Viral Strains
Miller, John F., Furfine, Eric S., Hanlon, Mary H., Hazen, Richard J., Ray, John A., Robinson, Laurence, Samano, Vicente, Spaltenstein, Andrew
Published in ChemInform (08.06.2004)
Published in ChemInform (08.06.2004)
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