PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis
Martin, Katherine, Pritchett, James, Llewellyn, Jessica, Mullan, Aoibheann F., Athwal, Varinder S., Dobie, Ross, Harvey, Emma, Zeef, Leo, Farrow, Stuart, Streuli, Charles, Henderson, Neil C., Friedman, Scott L., Hanley, Neil A., Piper Hanley, Karen
Published in Nature communications (18.08.2016)
Published in Nature communications (18.08.2016)
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Development of the Human Pancreas From Foregut to Endocrine Commitment
JENNINGS, Rachel E, BERRY, Andrew A, KIRKWOOD-WILSON, Rebecca, ROBERTS, Neil A, HEARN, Thomas, SALISBURY, Rachel J, BLAYLOCK, Jennifer, HANLEY, Karen Piper, HANLEY, Neil A
Published in Diabetes (New York, N.Y.) (01.10.2013)
Published in Diabetes (New York, N.Y.) (01.10.2013)
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Genetic Contribution to Non-alcoholic Fatty Liver Disease and Prognostic Implications
Martin, Katherine, Hatab, Anas, Athwal, Varinder S., Jokl, Elliot, Piper Hanley, Karen
Published in Current diabetes reports (01.03.2021)
Published in Current diabetes reports (01.03.2021)
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An integrative transcriptomic atlas of organogenesis in human embryos
Gerrard, Dave T, Berry, Andrew A, Jennings, Rachel E, Piper Hanley, Karen, Bobola, Nicoletta, Hanley, Neil A
Published in eLife (24.08.2016)
Published in eLife (24.08.2016)
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Journal Article
SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis
Athwal, Varinder S., Pritchett, James, Martin, Katherine, Llewellyn, Jessica, Scott, Jennifer, Harvey, Emma, Zaitoun, Abed M., Mullan, Aoibheann F., Zeef, Leo A. H., Friedman, Scott L., Irving, William L., Hanley, Neil A., Guha, Indra N., Piper Hanley, Karen
Published in Scientific reports (17.12.2018)
Published in Scientific reports (17.12.2018)
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Journal Article
PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis
Jokl, Elliot, Mullan, Aoibheann F., Simpson, Kara, Birchall, Lindsay, Pearmain, Laurence, Martin, Katherine, Pritchett, James, Raza, Sayyid, Shah, Rajesh, Hodson, Nigel W., Williams, Craig J., Camacho, Elizabeth, Zeef, Leo, Donaldson, Ian, Athwal, Varinder S., Hanley, Neil A., Piper Hanley, Karen
Published in Cell reports (Cambridge) (28.11.2023)
Published in Cell reports (Cambridge) (28.11.2023)
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Journal Article
SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis
Athwal, Varinder S, Pritchett, James, Llewellyn, Jessica, Martin, Katherine, Camacho, Elizabeth, Raza, Sayyid MA, Phythian‐Adams, Alexander, Birchall, Lindsay J, Mullan, Aoibheann F, Su, Kim, Pearmain, Laurence, Dolman, Grace, Zaitoun, Abed M, Friedman, Scott L, MacDonald, Andrew, Irving, William L, Guha, Indra N, Hanley, Neil A, Piper Hanley, Karen
Published in EMBO molecular medicine (01.12.2017)
Published in EMBO molecular medicine (01.12.2017)
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In humans, early cortisol biosynthesis provides a mechanism to safeguard female sexual development
Goto, Masahiro, Piper Hanley, Karen, Marcos, Josep, Wood, Peter J, Wright, Sarah, Postle, Anthony D, Cameron, Iain T, Mason, J Ian, Wilson, David I, Hanley, Neil A
Published in The Journal of clinical investigation (01.04.2006)
Published in The Journal of clinical investigation (01.04.2006)
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Laser Capture and Deep Sequencing Reveals the Transcriptomic Programmes Regulating the Onset of Pancreas and Liver Differentiation in Human Embryos
Jennings, Rachel E., Berry, Andrew A., Gerrard, David T., Wearne, Stephen J., Strutt, James, Withey, Sarah, Chhatriwala, Mariya, Piper Hanley, Karen, Vallier, Ludovic, Bobola, Nicoletta, Hanley, Neil A.
Published in Stem cell reports (14.11.2017)
Published in Stem cell reports (14.11.2017)
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Improving detection of cystic fibrosis related liver disease using liver fibrosis assessment tools
Scott, Jennifer A., Jones, Andrew M., Jokl, Elliot, Gordon-Walker, Timothy, Barry, Peter J., Hanley, Neil A., Piper Hanley, Karen, Athwal, Varinder S.
Published in Heliyon (01.11.2023)
Published in Heliyon (01.11.2023)
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Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells
Pritchett, James, Athwal, Varinder S, Harvey, Emma, Martin, Katherine, Llewellyn, Jessica, Ireland, Philip, Nicolaides, Alexander, Humphries, Martin J, Bobola, Nicoletta, Hanley, Neil A, Piper Hanley, Karen
Published in PloS one (27.06.2014)
Published in PloS one (27.06.2014)
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Health Technology Adoption in Liver Disease: Innovative Use of Data Science Solutions for Early Disease Detection
Bennett, Lucy, Purssell, Huw, Street, Oliver, Piper Hanley, Karen, Morling, Joanne R, Hanley, Neil A, Athwal, Varinder, Guha, Indra Neil
Published in Frontiers in digital health (28.01.2022)
Published in Frontiers in digital health (28.01.2022)
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The window period of NEUROGENIN3 during human gestation
Salisbury, Rachel J, Blaylock, Jennifer, Berry, Andrew A, Jennings, Rachel E, De Krijger, Ronald, Piper Hanley, Karen, Hanley, Neil A
Published in Islets (04.05.2014)
Published in Islets (04.05.2014)
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Prognostic and predictive factors for locoregional and systemic therapies in hepatocellular carcinoma
Gray, Simon, Lamarca, Angela, McNamara, Mairéad G., Edeline, Julien, Piper‐Hanley, Karen, Valle, Juan W., Hubner, Richard A.
Published in Liver cancer international (01.03.2023)
Published in Liver cancer international (01.03.2023)
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Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes
Baxter, Melissa, Withey, Sarah, Harrison, Sean, Segeritz, Charis-Patricia, Zhang, Fang, Atkinson-Dell, Rebecca, Rowe, Cliff, Gerrard, Dave T, Sison-Young, Rowena, Jenkins, Roz, Henry, Joanne, Berry, Andrew A, Mohamet, Lisa, Best, Marie, Fenwick, Stephen W, Malik, Hassan, Kitteringham, Neil R, Goldring, Chris E, Piper Hanley, Karen, Vallier, Ludovic, Hanley, Neil A
Published in Journal of hepatology (01.03.2015)
Published in Journal of hepatology (01.03.2015)
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In vitro expression of NGN3 identifies RAB3B as the predominant Ras-associated GTP-binding protein 3 family member in human islets
Piper Hanley, Karen, Hearn, Tom, Berry, Andrew, Carvell, Melanie J, Patch, Ann-Marie, Williams, Louise J, Sugden, Sarah A, Wilson, David I, Ellard, Sian, Hanley, Neil A
Published in Journal of endocrinology (01.11.2010)
Published in Journal of endocrinology (01.11.2010)
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